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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
281 Results for "
Fluorescent substrate
" in MedChemExpress (MCE) Product Catalog:
Products (281)
281 Results for "Fluorescent substrate" in MCE Product Catalog:
Cat. No.: HY-131030
CAS No.: 2127150-20-1
Synonyms: JF669, SE; JF669, NHS
Cat. No.: HY-137858
CAS No.: 125455-61-0
Synonyms: Gly-Arg-4-NA hydrochloride; GR-pNA hydrochloride; GR p-itoailide hydrochloride
Cat. No.: HY-W344383
CAS No.: 73554-90-2
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Cat. No.: HY-D3433
CAS No.: 222159-75-3
Synonyms: CDCSF
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5-Carboxy-2′,7′-dichlorosulfonefluorescein (CDCSF) is a fluorescein derivative-based fluorescent probe. 5-Carboxy-2′,7′-dichlorosulfonefluorescein serves as a fluorescent substrate for the organic anion transporting polypeptide OATP2B1, and is specifically recognized and transported into cells by OATP2B1 under acidic pH conditions, making it suitable for in vitro high-throughput screening of drug-drug interactions (DDI) and food-drug interactions (FDI) (Ex/Em = 485/535 nm) .
Synonyms: 4-MUB
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4-Methylumbelliferyl butyrate (4-MUB) is a fluorogenic esterase substrate that is hydrolyzed by esterases to release the fluorescent product 4-methylumbelliferone (HY-N0187). 4-Methylumbelliferyl butyrate is hydrolyzed by the general esterases (GE) of Daphnia magna and Chironomus riparius; it also serves as a substrate for the recombinant mycobacterial carboxylesterase MT2282 (CaeA). 4-Methylumbelliferyl butyrate is used to determine the activity of the S. aureus serine hydrolases FphB and FphH. 4-Methylumbelliferyl butyrate is used in studies related to esterase activity assays .
Cat. No.: HY-138658
Synonyms: JF526, SE; JF526, NHS
Cat. No.: HY-134360A
Synonyms: (y-AmNS)-ATP sodium
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ATP-1-Aminonaphthalene-5-sulfonate ((y-AmNS)-ATP) sodium is a fluorescent analog of ATP (HY-B2176). ATP-1-Aminonaphthalene-5-sulfonate is a substrate for DNA-dependent RNA polymerase and valyl t-RNA synthetase (Ex/Em = 320/460 nm) .
Cat. No.: HY-P4593
CAS No.: 66647-41-4
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closed-HMRG is an HMRG (HY-D2379) with a closed spiro-ring structure. HMRG is a fluorescent dye, which serves as the fluorescent active product generated by enzyme-activated fluorescent probes targeting proteases and glycosidases. Its detection mechanism relies on the intramolecular spirocyclization equilibrium: HMRG itself exists in an open non-spirocyclic structure under physiological pH, which maintains a conjugated π system and produces strong fluorescence; whereas its probe precursors (such as Leu-HMRG, Ac-GlyPro-HMRG and βGal-HMRG) exist in a closed spirocyclic form and show no fluorescence due to the disruption of the π-conjugated system; when the target enzyme cleaves the substrate fragment linked to the probe precursor, the closed spirocyclic structure converts to the open structure of HMRG, restoring the conjugated system and generating a strong fluorescent signal. Its detection wavelength is Ex/Em = 501/524 nm .
Cat. No.: HY-W750220
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4-Methylumbelliferyl β-D-glucuronide dihydrate is a fluorescent substrate and fluorescent probe used to detect the activity of β-D-glucuronidase. 4-Methylumbelliferyl β-D-glucuronide dihydrate also serves as a surrogate for assessing fecal coliform contamination in aquatic environments. 4-Methylumbelliferyl β-D-glucuronide dihydrate releases 4-methylumbelliferone via enzyme-mediated cleavage of the β-glycosidic bond; the latter emits fluorescence under alkaline conditions, with an excitation wavelength of 365-366 nm and an emission wavelength of 444 nm .
Cat. No.: HY-W928283
CAS No.: 1135372-06-3
Cat. No.: HY-131025
CAS No.: 1811539-88-4
Synonyms: JF585, SE; JF585, NHS
Synonyms: JF646, Tetrazine
Cat. No.: HY-110334
CAS No.: 1883548-88-6
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FFN 206 dihydrochloride, a fluorescent probe, is used as an excellent Vesicular Monoamine Transporter 2 (VMAT2) substrate with an apparent Km of 1.16 μM. FFN 206 dihydrochloride is capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles .
Cat. No.: HY-124324
CAS No.: 106927-48-4
Synonyms: p-Nitopheyl β-D-cellotioside
Cat. No.: HY-131009
Purity: 66.20%
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Fluorescein-NAD + is a fluorescent NAD + analog that can be used in studies related to the detection of ADP-ribosylation reactions. Fluorescein-NAD + enables visualization of ADP-ribose groups, thereby facilitating the detection of ADP-ribosylation reactions. Fluorescein-NAD + serves as a substrate for detecting the auto-ribosylation activity of SIRT6 and the ADP-ribosylation of RhoA by C3larvin toxin .
Cat. No.: HY-131009A
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Fluorescein-NAD + sodium is a fluorescent NAD + analog that can be used in studies related to the detection of ADP-ribosylation reactions. Fluorescein-NAD + sodium enables visualization of ADP-ribose groups, thereby facilitating the detection of ADP-ribosylation reactions. Fluorescein-NAD + sodium serves as a substrate for detecting the auto-ribosylation activity of SIRT6 and the ADP-ribosylation of RhoA by C3larvin toxin .
Cat. No.: HY-138241
CAS No.: 148185-52-8
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PBD-BODIPY is a probe for the spectrophotometric measurement of autoxidation reactions. Co-autoxidation of the PBD-BODIPY signal carrier and a hydrocarbon co-substrate can be quantified by monitoring loss of absorbance at 591 nm. PBD-BODIPY has been used to measure the activity of radical-trapping antioxidants in cell-free assays. It has also been used as a fluorescent probe for the detection of epoxidation activity.
Cat. No.: HY-139814
CAS No.: 1979130-73-8
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d-Phe-Pro-Arg-PABA-Resorufin is a selective Thrombin substrate. d-Phe-Pro-Arg-PABA-Resorufin can be cleaved by thrombin to release fluorescent and chromogenic products. d-Phe-Pro-Arg-PABA-Resorufin enables sensitive detection of the thrombin inhibitor Dabigatran (HY-10163) via thrombin-mediated cleavage attenuation .
Cat. No.: HY-187021
CAS No.: 81017-23-4
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3-Carboxyumbelliferyl acetate (compound ACC) is a fluorescent substrate that can be used to detect the activity of the Escherichia coli polysaccharide deacetylase PgaB, with a Km of 1.2 mM. 3-Carboxyumbelliferyl acetate undergoes acetate hydrolysis under the catalysis of E. coli PgaB. 3-Carboxyumbelliferyl acetate can be used in studies related to PgaB enzymatic activity and the mechanism of bacterial biofilm formation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
