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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
228 Results for "
LDL
" in MedChemExpress (MCE) Product Catalog:
Products (228)
228 Results for "LDL" in MCE Product Catalog:
Cat. No.: HY-P77990
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LRP6; Low Density Lipoprotein Receptor-Related Protein 6; LDL Receptor Related Protein 6; Low-Density Lipoprotein Receptor-Related Protein; Low-Density Lipoprotein Receptor-Related Protein 6; STHAG7; ADCAD2; OPTA4; LRP-6; EVR8
Species:
Human
Source:
HEK293
Cat. No.: HY-P700783
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRP10; DKFZP564C1940; LDL Receptor Related Protein 10; MGC8675; MSTP087; LRP-10; MST087; Low Density Lipoprotein Receptor-Related Protein 10; LRP9; LRP10 Protein; Low-Density Lipoprotein Receptor-Related Protein 10
Species:
Mouse
Source:
HEK293
Synonyms: SOM3355
Bevantolol hydrochloride (SOM3355) is a selective β1-adrenergic receptor antagonist, with an IC50 of 35 nM for β1-adrenergic receptor and an IC50 of 60 nM for VMAT2. Bevantolol hydrochloride blocks β1-adrenergic receptors, exerts partial agonistic effects on α-adrenoceptor, inhibits calcium currents in the sinoatrial and atrioventricular nodes as well as sodium currents in cardiomyocytes, delays repolarization, and shortens the action potential duration of Purkinje cells. Bevantolol hydrochloride reduces peripheral vascular resistance, increases subendocardial blood flow, inhibits VMAT2, elevates the serum HDL/LDL ratio, and does not affect glomerular filtration rate or cause cold extremities. Bevantolol hydrochloride is applicable to research related to angina pectoris, hypertension, arrhythmia, and Huntington's disease .
Cat. No.: HY-A0249
CAS No.: 59170-23-9
Synonyms: SOM3355 free base
Research Areas:
Bevantolol (SOM3355 (free base)) is a selective β1-adrenergic receptor antagonist, with an IC50 of 35 nM for β1-adrenergic receptor and an IC50 of 60 nM for VMAT2. Bevantolol blocks β1-adrenergic receptors, exerts partial agonistic effects on α-adrenoceptor, inhibits calcium currents in the sinoatrial and atrioventricular nodes as well as sodium currents in cardiomyocytes, delays repolarization, and shortens the action potential duration of Purkinje cells. Bevantolol reduces peripheral vascular resistance, increases subendocardial blood flow, inhibits VMAT2, elevates the serum HDL/LDL ratio, and does not affect glomerular filtration rate or cause cold extremities. Bevantolol is applicable to research related to angina pectoris, hypertension, arrhythmia, and Huntington's disease .
Cat. No.: HY-P78837
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LRP6; Low Density Lipoprotein Receptor-Related Protein 6; LDL Receptor Related Protein 6; Low-Density Lipoprotein Receptor-Related Protein; Low-Density Lipoprotein Receptor-Related Protein 6; STHAG7; ADCAD2; OPTA4; LRP-6; EVR8
Species:
Human
Source:
HEK293
Cat. No.: HY-P702553
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SCARF1; Scavenger Receptor Expressed By Endothelial Cells 1; Scavenger Receptor Class F Member 1; SREC-I; Acetyl LDL Receptor; Scavenger Receptor Expressed By Endothelial Cells; SREC; Scavenger Receptor Class F, Member 1; KIAA0149; Alternative Protein SCA
Species:
Human
Source:
HEK293
Cat. No.: HY-P704737
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LRP2; LRP-2; LDL Receptor Related Protein 2; Low Density Lipoprotein Receptor-Related Protein II; Megalin; Low Density Lipoprotein Receptor-Related Protein 2; Gp330; Heymann Nephritis Antigen Homolog; Low-Density Lipoprotein Receptor-Related Protein 2; Un
Species:
Human
Source:
HEK293
Cat. No.: HY-P76783
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MSR1; Macrophage Acetylated LDL Receptor I And II; Macrophage Scavenger Receptor 1; Scavenger Receptor Class A Member 1; SCARA1; CDNA FLJ55770, Highly Similar To Macrophage Scavenger Receptor Types I And II; SR-AIII; Macrophage Scavenger Receptor Type III
Species:
Rat
Source:
HEK293
Cat. No.: HY-P76784
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MSR1; Macrophage Acetylated LDL Receptor I And II; Macrophage Scavenger Receptor 1; Scavenger Receptor Class A Member 1; SCARA1; CDNA FLJ55770, Highly Similar To Macrophage Scavenger Receptor Types I And II; SR-AIII; Macrophage Scavenger Receptor Type III
Species:
Rat
Source:
HEK293
Cat. No.: HY-P705715
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRP2; LRP-2; LDL Receptor Related Protein 2; Low Density Lipoprotein Receptor-Related Protein II; Megalin; Low Density Lipoprotein Receptor-Related Protein 2; Gp330; Heymann Nephritis Antigen Homolog; Low-Density Lipoprotein Receptor-Related Protein 2; Un
Species:
Human
Source:
E. coli
Cat. No.: HY-182469
Target:
Lactate Dehydrogenase AMPK FOXO Interleukin Related Reactive Oxygen Species (ROS) TNF Receptor Bcl-2 Family Caspase Apoptosis
Research Areas:
FuBIG is an iminoguanidine derivative with neuroprotective effects. FuBIGL inhibits L-LDH activation and reduces lactate production. FuBIGL exerts protective effects on inflammatory nerve cells, upregulates the expressions of AMPK, pAMPK and FOXO3, and activates the AMPK pathway in cells. FuBIG exerts anti-inflammatory effects by reducing pro-inflammatory cytokines (IL-6, IL-1β, TNF-α) and increasing the anti-inflammatory cytokine IL-10. FuBIG maintains mitochondrial membrane potential, alleviates mitochondrial dysfunction, reduces ROS production, and relieves oxidative stress. FuBIG upregulates Bcl-2, downregulates Bax and Caspase-3, and inhibits cell apoptosis (apoptosis). FuBIG improves metabolic disorders in diabetic mice, decreases the levels of LDL-C, ALT and AST, and increases HDL-C level simultaneously. FuBIG can be used in the research of diabetic neuroinflammation .
Cat. No.: HY-N11846
CAS No.: 68978-09-6
Cat. No.: HY-W015600R
CAS No.: 614-80-2
Synonyms: Orthocetamol (Standard)
Research Areas:
2-Acetamidophenol (Standard) is the analytical standard of 2-Acetamidophenol. This product is intended for research and analytical applications. 2-Acetamidophenol (Orthocetamol) is a regulator that targets ferroptosis and glutathione metabolic pathways, is the ortho-regioisomer of Paracetamol (HY-66005). 2-Acetamidophenol has anti-atherosclerotic activity, and inhibiting total cholesterol (TC) and triglyceride (TG) in a zebrafish hyperlipidemia model with IC50s for 30 μM and 40 μM, respectively. 2-Acetamidophenol upregulates the expression of glutathione synthesis-related genes (such as GCLC, GCLM, GSS) and iron ion transport genes (such as FPN1, FTH), reduces the accumulation of intracellular reactive oxygen species (ROS) and ferrous ions (Fe 2+), and enhances the activity of glutathione peroxidase GPX4, thereby inhibiting macrophage phagocytosis of oxidized low-density lipoprotein (ox-LDL) and foam cell formation .
Cat. No.: HY-W015600S
CAS No.: 122258-87-1
Synonyms: Orthocetamol-d3
Cat. No.: HY-P70946
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRP12; FLJ12929; LDL Receptor Related Protein 12; Low Density Lipoprotein Receptor-Related Protein 12; ST7; MIG13A; Low-Density Lipoprotein Receptor-Related Protein 12; LRP-12; Suppressor Of Tumorigenicity 7 Protein; ALS28; LDLR-Related Protein 12
Species:
Human
Source:
HEK293
Cat. No.: HY-P705712
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRP2; LRP-2; LDL Receptor Related Protein 2; Low Density Lipoprotein Receptor-Related Protein II; Megalin; Low Density Lipoprotein Receptor-Related Protein 2; Gp330; Heymann Nephritis Antigen Homolog; Low-Density Lipoprotein Receptor-Related Protein 2; Un
Species:
Human
Source:
HEK293
Cat. No.: HY-P705713
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRP2; LRP-2; LDL Receptor Related Protein 2; Low Density Lipoprotein Receptor-Related Protein II; Megalin; Low Density Lipoprotein Receptor-Related Protein 2; Gp330; Heymann Nephritis Antigen Homolog; Low-Density Lipoprotein Receptor-Related Protein 2; Un
Species:
Human
Source:
HEK293
Cat. No.: HY-P705714
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRP2; LRP-2; LDL Receptor Related Protein 2; Low Density Lipoprotein Receptor-Related Protein II; Megalin; Low Density Lipoprotein Receptor-Related Protein 2; Gp330; Heymann Nephritis Antigen Homolog; Low-Density Lipoprotein Receptor-Related Protein 2; Un
Species:
Human
Source:
HEK293
Cat. No.: HY-121186R
CAS No.: 42864-78-8
Synonyms: SOM3355 (Standard)
Bevantolol hydrochloride (Standard) (SOM3355 (Standard)) is the analytical standard of Bevantolol hydrochloride (HY-121186). This product is intended for research and analytical applications. Bevantolol hydrochloride (SOM3355) is a selective β1-adrenergic receptor antagonist, with an IC50 of 35 nM for β1-adrenergic receptor and an IC50 of 60 nM for VMAT2. Bevantolol hydrochloride blocks β1-adrenergic receptors, exerts partial agonistic effects on α-adrenoceptor, inhibits calcium currents in the sinoatrial and atrioventricular nodes as well as sodium currents in cardiomyocytes, delays repolarization, and shortens the action potential duration of Purkinje cells. Bevantolol hydrochloride reduces peripheral vascular resistance, increases subendocardial blood flow, inhibits VMAT2, elevates the serum HDL/LDL ratio, and does not affect glomerular filtration rate or cause cold extremities. Bevantolol hydrochloride is applicable to research related to angina pectoris, hypertension, arrhythmia, and Huntington's disease .
Cat. No.: HY-121186S
Synonyms: SOM3355-d7
Research Areas:
Bevantolol-d7 hydrochloride (SOM3355-d7) is the d7-labeled Bevantolol hydrochloride (HY-121186). Bevantolol hydrochloride (SOM3355) is a selective β1-adrenergic receptor antagonist, with an IC50 of 35 nM for β1-adrenergic receptor and an IC50 of 60 nM for VMAT2. Bevantolol hydrochloride blocks β1-adrenergic receptors, exerts partial agonistic effects on α-adrenoceptor, inhibits calcium currents in the sinoatrial and atrioventricular nodes as well as sodium currents in cardiomyocytes, delays repolarization, and shortens the action potential duration of Purkinje cells. Bevantolol hydrochloride reduces peripheral vascular resistance, increases subendocardial blood flow, inhibits VMAT2, elevates the serum HDL/LDL ratio, and does not affect glomerular filtration rate or cause cold extremities. Bevantolol hydrochloride is applicable to research related to angina pectoris, hypertension, arrhythmia, and Huntington's disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
