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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
48 Results for "
ARN
" in MedChemExpress (MCE) Product Catalog:
Products (48)
48 Results for "ARN" in MCE Product Catalog:
Cat. No.: HY-16060S
CAS No.: 1638885-65-0
Synonyms: ARN-509-d4
Cat. No.: HY-171145
CAS No.: 1224198-85-9
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ATP-ArN3 is a UV-activatable ATP-crosslinker analog. ATP-ArN3 relys on UV irradiation to activate the aryl azide (ArN3) crosslinking group and conjugate substrate to kinases and associated proteins .
Cat. No.: HY-176287
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ARN25657 is a dual-acting D3R/GSK-3β modulator. ARN25657 has both partial D3R agonist activity (EC50 = 15.2 nM, Ki =1.5 nM) and potent GSK-3β inhibitor activity (IC50 = 19.3 nM). ARN25657 exhibits excellent GSK-3β selectivity over FYN, PKA, and CDK5/p35. ARN25657 inhibits P-glycoprotein (P-gP)-mediated acetoxymethyl calcein efflux and improves in vitro ADME properties while maintaining a balanced dual-target profile. ARN25657 is useful for studying bipolar disorder and related neuropsychiatric disorders .
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ARN19874 is a selective, reversible uncompetitive N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) activity inhibitor with an IC50 of ~34 μM .
Cat. No.: HY-16060S1
CAS No.: 1638885-61-6
Synonyms: ARN-509-d3
Cat. No.: HY-16060R
CAS No.: 956104-40-8
Synonyms: ARN-509 (Standard)
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Apalutamide (Standard) is the analytical standard of Apalutamide. This product is intended for research and analytical applications. Apalutamide (ARN-509) is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM .
Cat. No.: HY-133569
CAS No.: 2244458-40-8
ARN23765 is a corrector for F508del-CFTR with an EC50 of 38 pM in human bronchial epithelial cells. ARN23765 improves the maturation and function of F508del-CFTR on the cell membrane, affects the ions transport and secretion, and corrects the pathological mechanism of cystic fibrosis (CF) .
Cat. No.: HY-16060S3
Synonyms: ARN-509-d7
Cat. No.: HY-16060S2
Synonyms: ARN-509-13C,d3
Cat. No.: HY-N6256
CAS No.: 108906-69-0
Category:
Cardiovascular Disease Triterpenes Terpenoids Aquifoliaceae Extract Plants Disease Research Fields Tabernaemontana elegans Stapf
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Cat. No.: HY-115777
CAS No.: 1675206-11-7
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ARN-6039 is an orally available inverse agonist of RORγ for autoimmune demyelinating disease.
Cat. No.: HY-148719
CAS No.: 2699768-78-8
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ARN24139(compound 3f) is a topoisomerase II (topoII) inhibitor with the IC50 of 7.3 μM. ARN24139 can inhibit cancer cell proliferation and is well tolerated in vivo .
Cat. No.: HY-103691
CAS No.: 1287451-26-6
ARN5187 is a lysosomotropic REV-ERBβ ligand with a dual inhibitory activity toward REV-ERB-mediated transcriptional regulation and autophagy. ARN5187 shows lysosomotropic potency and cytotoxicity. ARN5187 induces apoptosis .
Cat. No.: HY-174800
CAS No.: 2230854-98-3
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ARN21929 is a Topoisomerase II inhibitor with an IC50 of 4.5 μM. ARN21929 exhibits excellent kinetic and thermodynamic solubility as well as metabolic stability. However, ARN21929 shows poor antiproliferative activity against A549, DU145, MCF7, HeLa, and A375 cells. ARN21929 can be used in the study of cancer .
Cat. No.: HY-125384
CAS No.: 1628345-10-7
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ARN14686 is an activity-based protein profiling (ABPP) probe. ARN14686 inhibits hNAAA with high potency (IC50=0.006 μM). ARN14686 interacts with NAAA via covalent binding to the N-terminal cysteine. ARN14686 binds only to the catalytically active form of NAAA, and may serve therefore as an efficient activity-based probe .
Cat. No.: HY-132882
CAS No.: 2320521-34-2
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ARN19689 is a potent, selective, orally active and non-covalent inhibitor of N Acylethanolamine-Hydrolyzing Acid Amidase (NAAA), with an IC50 of 42 nM. ARN19689 is a promising pharmacological tool to be further investigated in the field of inflammatory conditions .
Cat. No.: HY-147265A
Eldocasiran sodium is a micro-ARN-193a-3p analogue, Eldocasiran sodium has anticancer activity, and can be used for cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
