74 Results for "

BK

" in MedChemExpress (MCE) Product Catalog:
Products (74)

74 Results for "BK" in MCE Product Catalog:

Cat. No.: HY-150048
CAS No.: 2204291-78-9
Target:  

CD73 Apoptosis

Research Areas:  

Cancer

BK50164 is a potent CD73 inhibitor with an IC50 value of 13.089 μM. BK50164 binds to CD99 with a KD value of 1.5 μM. BK50164 shows antiproliferative activity. BK50164 induced Apoptosis and cell cycle arrest at Sub-G1 phase .
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Cat. No.: HY-19071
CAS No.: 110008-56-5
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

BK-218 is an orally active cephalosporin antibiotic that binds to penicillin-binding proteins (PBPs) and has a greater inhibitory effect than Cephalexin (HY-B0200) and Cefoxitin (HY-B1825). BK-218 has similar antibacterial activity to Cefamandole (HY-B1128) and can be used in the development of antibacterial drugs .
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Cat. No.: HY-106277A
CAS No.: 869880-33-1
Synonyms: MEN16132
Target:  

Bradykinin Receptor

Research Areas:  

Metabolic Disease

Fasitibant chloride hydrochloride (MEN16132) is a potent, selective, high affinity, and long-lasting nonpeptide bradykinin B2 (BK2) receptor antagonist. Fasitibant chloride hydrochloride has proinflammatory effects and can be used for the research of osteoarthritis and rheumatoid arthritis .
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Cat. No.: HY-P991153
CAS No.: 2923558-06-7

Target:  

Virus Protease

Research Areas:  

Infection

Potravitug is a humanized immunoglobulin G1-κ monoclonal antibody targeting the major capsid protein VP1 of BK polyomavirus (BKV). Potravitug is promising for research of BKV-infection-related diseases, such as BKV-induced nephropathy after organ transplantation .
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Cat. No.: HY-B0330C
CAS No.: 872606-49-0
Synonyms: (-)-Ofloxacin sodium
Levofloxacin ((-)-Ofloxacin) sodium is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin sodium inhibits the DNA gyrase and topoisomerase IV. Levofloxacin sodium can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin sodium shows anti-orthopoxvirus activity .
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Cat. No.: HY-150885
CAS No.: 330785-90-5
Research Areas:  

Cancer

BTK ligand 1 (compound 1) is a ligand targeting Bruton’s tyrosine kinase (Btk). BTK ligand 1 can combine with E3 ligase ligand (Ligand for E3 Ligase) through PROTAC Linker to form PROTAC. PROTACs targeting Btk can be used in the study of chronic lymphocytic leukemia (CLL) and other BK cell malignancies .
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Cat. No.: HY-B0330AR
CAS No.: 138199-71-0
Synonyms: Levofloxacin hemihydrate (Standard)
Levofloxacin (hydrate) (Standard) is the analytical standard of Levofloxacin (hydrate). This product is intended for research and analytical applications. Levofloxacin hydrate (Levofloxacin hemihydrate) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrate inhibits the DNA gyrase and topoisomerase IV. Levofloxacin hydrate can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin hydrate shows anti-orthopoxvirus activity .
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Cat. No.: HY-W714396
CAS No.: 2726084-56-4
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

bk-EABDI hydrochloride is a drug derivative characterized by an ethyl group at the alpha position as well as an N-terminal ethyl group.
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Cat. No.: HY-RS07411
Research Areas:  

Others

KNG1 Human Pre-designed siRNA Set A contains three designed siRNAs for KNG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P1721
CAS No.: 147267-10-5
Target:  

Bradykinin Receptor

Research Areas:  

Cardiovascular Disease

NPC 17731 is a new bradykinin (BK) receptor antagonist. NPC 17731 antagonized both the contractile and relaxant responses caused by BK in longitudinal smooth muscle with IC50 of 23 and 29 nM, respectively .
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Cat. No.: HY-P1694
CAS No.: 103412-37-9
Target:  

Bradykinin Receptor

Research Areas:  

Cardiovascular Disease

B4148 is a selective competitive bradykinin (BK) antagonist that significantly inhibits BK-induced hypotension in rats. In a rat model of endotoxin shock induced by Escherichia coli lipopolysaccharide, B4148 significantly attenuated the decrease in mean arterial blood pressure compared with the control group .
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Cat. No.: HY-133614
CAS No.: 5673-36-9
Target:  

Potassium Channel

Research Areas:  

Others

Dihydroisopimaric acid activates large conductance Ca 2+ activated K + (BK) channels alphabeta1 in the direct measurement of BKalphabeta1 opening under whole-cell voltage clamp .
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Cat. No.: HY-12655
CAS No.: 1417537-93-9
Target:  

MMP

Research Areas:  

Metabolic Disease

IDE-IN-1 (compound 6bK) is an insulin-degrading enzyme (IDE) inhibitor with IC50 value of 50 nM. IDE-IN-1 can be used to study type 2 diabetes .
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Cat. No.: HY-P1281
CAS No.: 145199-73-1
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

Kaliotoxin is a peptidyl inhibitor of neuronal BK-Type. Kaliotoxin can specific inhibit Kv channels and calcium-activated potassium channels. Kaliotoxin can be used for the research of the regulation of membrane potential and neuron excitability .
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Cat. No.: HY-106277
CAS No.: 869939-83-3
Target:  

Bradykinin Receptor

Research Areas:  

Metabolic Disease

Fasitibant (free base) is a potent, selective, high affinity, and long-lasting nonpeptide bradykinin B2 (BK2) receptor antagonist. Fasitibant (free base) has proinflammatory effects and can be used for the research of osteoarthritis and rheumatoid arthritis .
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Cat. No.: HY-103289
CAS No.: 235082-52-7
Purity:  99.15%
MEN 11270, a cyclic decapeptide, is a B2 kinin receptor antagonist. MEN 11270 bound with high-affinity to the B2 kinin receptor constitutively expressed by WI38 human fibroblasts, inhibiting 3H-bradykinin (BK) with a pKi value of 10.3 .
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Cat. No.: HY-120506
CAS No.: 127819-95-8
Target:  

Bradykinin Receptor

Research Areas:  

Others

L-366811 is a compound with bradykinin agonist activity, with activity to stimulate phosphatidylinositol turnover and induce uterine contraction. L-366811 stimulates phosphatidylinositol turnover in rat uterine slices and induces rat uterine contraction in vitro, with moderate affinity for the [3H]BK binding site.
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Cat. No.: HY-W338859
CAS No.: 226578-51-4
Research Areas:  

Infection Cancer

Levofloxacin mesylate is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin mesylate inhibits the DNA gyrase and topoisomerase IV. Levofloxacin mesylate can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin mesylate shows anti-orthopoxvirus activity .
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Cat. No.: HY-133596
CAS No.: 65281-77-8
Research Areas:  

Neurological Disease

12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, is a potent Ca 2+-activated K + (BK) channel opener. 12,14-Dichlorodehydroabietic acid blocks GABA-dependent chloride entry in mammalian brain and operates as a non-competitive GABAA antagonist. 12,14-Dichlorodehydroabietic acid increases cytosolic free Ca 2+ and stimulates transmitter release .
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Cat. No.: HY-106916
CAS No.: 120373-36-6
Purity:  ≥99.0%
Unoprostone, a prostaglandin F2α analog, is a large conductance Ca 2+-activated K + (BK) channels and ClC-2 type chloride channels activator. Unoprostone reduces oxidative stress- and light-induced retinal cell death, and phagocytotic dysfunction. Unoprostone reduces intraocular pressure and can be used for the study of glaucoma, ocular hypertension and retinitis pigmentosa .
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