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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
77 Results for "
erythroid
" in MedChemExpress (MCE) Product Catalog:
Products (77)
77 Results for "erythroid" in MCE Product Catalog:
Cat. No.: HY-P3598
CAS No.: 57468-16-3
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Cat. No.: HY-17363S
CAS No.: 66487-95-4
Cat. No.: HY-152037
CAS No.: 2417117-84-9
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AChE/Nrf2 modulator 1 is an orally active acetylcholinesterase (AChE)/nuclear factor erythroid 2-related factor 2 (Nrf2) modulator. AChE/Nrf2 modulator 1 has Nrf2 inductive activity and AChE inhibitory activity for eeAChE and hAChE with IC50 values of 0.07 μM and 0.38 μM, respectively. AChE/Nrf2 modulator 1 can be used for the research of Alzheimer's disease .
Cat. No.: HY-178997
CAS No.: 3070514-51-8
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NFE2L1 activator-1 (Compound 5b) is a potent nuclear factor erythroid 2-related factor 1 (NFE2L1) activator (EC50 = 2.4 µM). NFE2L1 activator-1 effectively resists ferroptosis (Ferroptosis). NFE2L1 activator-1 can specifically activate the NFE2L1 signaling pathway to upregulate GPX4, PSMB7, PSMC4. NFE2L1 activator-1 can be used in cancer research .
Cat. No.: HY-163315
CAS No.: 2414391-44-7
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Cat. No.: HY-P3761
CAS No.: 147821-01-0
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Cat. No.: HY-177944
CAS No.: 2829198-49-2
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DC-PGKI is an orally active ATP-competitive PGK1 inhibitor(IC50 = 0.16 Μm, Kd = 99.08 nM). DC-PGKI stabilizes PGK1 in vitro and in vivo, and suppresses both glycolytic activity and the kinase function of PGK1. DC-PGKI-mediated inhibition of PGK1 leads to the accumulation of NRF2 (nuclear factor-erythroid factor 2-related factor 2, NFE2L2), which then translocates to the nucleus, binds to the proximal regions of IL-1β and IL-6 genes, and suppresses the LPS-induced expression of these genes. DC-PGKI can be used for the study of colitis .
Cat. No.: HY-118964
CAS No.: 151013-48-8
Tyrphostin AG 568 is a tyrphostin tyrosine kinase inhibitor that induces erythroid differentiation. Tyrphostin AG 568 can be utilized in research related to autologous bone marrow transplantation .
Cat. No.: HY-10966R
CAS No.: 405554-55-4
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SB-590885 (Standard) is the analytical standard of SB-590885 (HY-10966). This product is intended for research and analytical applications. SB-590885 is a BRAF/c-Raf kinase inhibitor that selectively targets B-Raf, and it amplifies the ERK/MAPK signaling pathway in RAS-activated cells. SB-590885 effectively inhibits the malignant proliferation, transformation and tumorigenicity of oncogenic B-Raf cells; it also induces the proliferation of erythroid progenitor cells, delays their differentiation and promotes hemoglobin synthesis, thereby improving ineffective erythropoiesis and reducing apoptosis. SB-590885 exerts a synergistic effect with TGF-β inhibitors and glucocorticoids, significantly promoting the formation of erythroid colonies in cells from patients with Diamond-Blackfan anemia (DBA). SB-590885 is mainly used in relevant studies on DBA, cisplatin-induced myelosuppression-related anemia, and pan-cancers such as melanoma and colorectal cancer .
Cat. No.: HY-110093
CAS No.: 1255517-77-1
UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 of 15 nM and 19 nM, respectively. UNC0638 hydrate inhibits TNBC cell invasion and migration in vitro. UNC0638 hydrate is also an inhibitor of EHMT1/2 and induces fetal hemoglobin (HbF) expression in human erythroid progenitor cell culture. In addition, UNC0638 hydrate has anti-FMDV (foot-and-mouth disease virus) and anti-VSV (vesicular stomatitis virus) activities, with excellent potency and selectivity against multiple epigenetic and non-epigenetic targets .
Cat. No.: HY-B1719AR
CAS No.: 50-10-2
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Oxyphenonium bromide Standard is the analytical standard of Oxyphenonium bromide (HY-B1719A). This product is intended for research and analytical applications. Oxyphenonium bromide is an orally effective competitive muscarinic acetylcholine receptor (mAChR) antagonist. Oxyphenonium bromide competitively binds to and blocks mAChR, thereby inhibiting the parasympathetic pathway. By inhibiting CHRM4, Oxyphenonium bromide increases cAMP levels and activates the CREB transcriptional program, thereby promoting erythroid progenitor cell expansion. Oxyphenonium bromide can be used in research on asthma, anemia, and gastric ulcers .
Cat. No.: HY-P76136
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AHSP; Alpha-Hemoglobin-Stabilizing Protein; Prev. ERAF; erythroid-Associated Factor; EDRF; erythroid Differentiation Associated Factor; erythroid Differentiation-Related Factor; erythroid Associated Factor; Alpha Hemoglobin Stabilizing Protein; Alpha Hemo
Species:
Human
Source:
E. coli
Cat. No.: HY-P72308A
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NFE2L2; Nuclear Factor (erythroid-Derived 2)-Like 2; NFE2 Like BZIP Transcription Factor 2; Nuclear Factor, erythroid Derived 2, Like 2; NRF2; Nuclear Factor erythroid-Derived 2-Like 2; Nuclear Factor erythroid 2-Related Factor 2; Nuclear Factor, erythroid 2-Like 2; NRF-2; NFE2-Related Factor 2; Nuclear Factor, erythroid 2 Like 2; IMDDHH; NF-E2-Related Factor 2; Nrf-2; Nuclear Factor erythroid-Derived 2-Like 2 Transcript Variant 1
Species:
Human
Source:
E. coli
Cat. No.: HY-P704943
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NFE2L2; Nuclear Factor (erythroid-Derived 2)-Like 2; NFE2 Like BZIP Transcription Factor 2; Nuclear Factor, erythroid Derived 2, Like 2; NRF2; Nuclear Factor erythroid-Derived 2-Like 2; Nuclear Factor erythroid 2-Related Factor 2; Nuclear Factor, Erythroi
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-108864
CAS No.: 113427-24-0
Synonyms: Epogen
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Cat. No.: HY-10966G
CAS No.: 405554-55-4
Cat. No.: HY-P7S1785
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; Nrf-2; Nuclear factor, erythroid derived 2, like 2; NFE2L2; NRF2
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
