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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
57 Results for "
human LDL
" in MedChemExpress (MCE) Product Catalog:
Products (57)
57 Results for "human LDL" in MCE Product Catalog:
Cat. No.: HY-147279
CAS No.: 2643306-81-2
Milpocitide is a low-density lipoprotein receptor (human LDL receptor, LDLR), (293-333)-peptide fragment (EGF-like domain 1) .
Cat. No.: HY-167870
CAS No.: 116181-54-5
Target:
Cat. No.: HY-115357
CAS No.: 1000998-62-8
Target:
Research Areas:
BMS711939 is a selective agonist for peroxisome proliferator-activated receptor α (PPAR α), with EC50 of 4 nM and 4.5 μM, for human PPARα and human PPARγ. BMS711939 exhibits good pharmacokinetic characters in rats models. BMS711939 increases HDL cholesterol, reduces LDL cholesterol and triglycerides .
Cat. No.: HY-W010697S
Cholesteryl linoleate-d11 is the d11-labeled Cholesteryl linoleate (HY-W010697). Cholesteryl linoleate is a cholesteryl ester with antibacterial activity that is present in low-density lipoprotein (LDL) particles, human nasal fluid, and respiratory epithelial secretions. Cholesteryl linoleate is oxidized by 12/15-lipoxygenase in macrophages and participates in selective uptake and efflux via LDL receptor-related protein. Cholesteryl linoleate does not induce endothelial adhesion molecule expression, nor does it induce monocyte binding to endothelial cells. Cholesteryl linoleate liposomal formulations inhibit the growth of multiple bacteria at physiological nasal fluid concentrations and act synergistically with antimicrobial peptides. Cholesteryl linoleate is useful for research related to atherosclerosis and bacterial infections .
Cat. No.: HY-106818A
CAS No.: 103379-03-9
Synonyms: AJ-2615
Target:
Research Areas:
Monatepil (AJ-2615 free base) maleate is a calcium antagonist with potent α1-adrenoceptor blocking activity. Monatepil maleate inhibits vasopressin- or methacholine-induced ischemic electrocardiographic changes in a rat model of vasospastic angina and reduces the mean arterial pressure in anesthetized rats. Monatepil maleate also enhances low-density lipoprotein (LDL) receptor activity in human skin fibroblasts . Monatepil maleate can be used in research related to hypertension, atherosclerosis, hyperlipidemia and vasospastic angina .
Cat. No.: HY-15790S
Synonyms: A 3309-d5; AZD 7806-d5
Cat. No.: HY-15790R
CAS No.: 439087-18-0
Synonyms: A 3309 (Standard); AZD 7806 (Standard)
Research Areas:
Elobixibat (Standard) is the analytical standard of Elobixibat (HY-15790). This product is intended for research and analytical applications. Elobixibat (A 3309; AZD 7806) is orally active, bile acid transporter (IBAT) inhibitor with IC50 values ??of 0.53 nM (human IBAT), 0.13 nM (mouse IBAT), and 5.8 nM (canine IBAT). Elobixibat can lower LDL cholesterol, increase serum GLP-1, promote colonic motility, and has the potential to treat metabolic syndrome. Elobixibat can be used in the study of chronic functional constipation (CIC), dyslipidemia, non-alcoholic hepatitis, and liver tumors in the elderly .
Cat. No.: HY-P70993
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; Lp-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plasma); GVIIA-PLA2; 1-Alkyl-2-Acetylglycerophosphocholine Esterase; Lipoprotein-Associated Phospholipase A2; 2-Acetyl-1-Alkylglycerophosphocholine Esterase; PAFAD; Platelet-Activating Factor Acetylhydrolase
Species:
Human
Source:
HEK293
Cat. No.: HY-P81172
Synonyms: Lectin-type oxidized LDL receptor 1; OLR1; lectin-like low density lipoprotein receptor-1; Oxidized low-density lipoprotein receptor 1; Ox-LDL receptor 1; Lectin-like oxidized LDL receptor 1; Lectin-like oxLDL receptor 1; LOX-1; BLOX1; Contains: Oxidized low-density lipoprotein receptor 1, soluble form A; Oxidized low-density lipoprotein receptor 1, soluble form B; OLR1_human.
Cat. No.: HY-P71369
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TINAGL1; Lipocalin 7; Prev. LCN7; OLRG-2; TINAGRP; Tubulointerstitial Nephritis Antigen-Like 1, Isoform CRA_a; P3ECSL; Oxidized LDL-Responsive Gene 2 Protein; LIECG3; Oxidized-LDL Responsive Gene 2; ARG1; Androgen Regulated Gene 1; Tubulointerstitial Neph
Species:
Human
Source:
HEK293
Cat. No.: HY-106818
CAS No.: 103377-41-9
Synonyms: AJ-2615 free base
Target:
Research Areas:
Monatepil (AJ-2615 free base) is a calcium antagonist with potent α1-adrenoceptor blocking activity. Monatepil inhibits vasopressin- or methacholine-induced ischemic electrocardiographic changes in a rat model of vasospastic angina and reduces the mean arterial pressure in anesthetized rats. Monatepil also enhances low-density lipoprotein (LDL) receptor activity in human skin fibroblasts . Monatepil can be used in research related to hypertension, atherosclerosis, hyperlipidemia and vasospastic angina .
Cat. No.: HY-106818B
CAS No.: 103379-02-8
Synonyms: AJ-2615 hydrochloride
Target:
Research Areas:
Monatepil (AJ-2615 free base) hydrochloride is a calcium antagonist with potent α1-adrenoceptor blocking activity. Monatepil hydrochloride inhibits vasopressin- or methacholine-induced ischemic electrocardiographic changes in a rat model of vasospastic angina and reduces the mean arterial pressure in anesthetized rats. Monatepil hydrochloride also enhances low-density lipoprotein (LDL) receptor activity in human skin fibroblasts . Monatepil hydrochloride can be used in research related to hypertension, atherosclerosis, hyperlipidemia and vasospastic angina .
Cat. No.: HY-149310A
CAS No.: 2743448-41-9
Target:
Research Areas:
Dim16 hydrochloride is a dual PCSK9 inhibitor and HMG-CoAR inhibitor, with an IC50 of 0.8 nM against human PCSK9 and an IC50 of 146.8 μM against HMG-CoAR. Dim16 hydrochloride disrupts the PCSK9-LDLR protein-protein interaction, inhibits the catalytic activity of HMG-CoAR, enhances cellular uptake of extracellular LDL, and suppresses PCSK9-induced platelet aggregation. Dim16 hydrochloride can be used in research related to hypercholesterolemia .
Cat. No.: HY-P704756
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LDLR; LDL Receptor; Low Density Lipoprotein Receptor; Low-Density Lipoprotein Receptor Class A Domain-Containing Protein 3; Low-Density Lipoprotein Receptor; Familial Hypercholesterolemia; LDLCQ2; Low Density Lipoprotein
Species:
Human
Source:
HEK293
Cat. No.: HY-182569
CAS No.: 132340-44-4
Category:
Target:
Cat. No.: HY-P704757
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LDLR; LDL Receptor; Low Density Lipoprotein Receptor; Low-Density Lipoprotein Receptor Class A Domain-Containing Protein 3; Low-Density Lipoprotein Receptor; Familial Hypercholesterolemia; LDLCQ2; Low Density Lipoprotein
Species:
Human
Source:
HEK293
Cat. No.: HY-P700860
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LDLR; LDL Receptor; Low Density Lipoprotein Receptor; Low-Density Lipoprotein Receptor Class A Domain-Containing Protein 3; Low-Density Lipoprotein Receptor; Familial Hypercholesterolemia; LDLCQ2; Low Density Lipoprotein
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
