2898 Results for "

intermediate

" in MedChemExpress (MCE) Product Catalog:
Products (2898)

2898 Results for "intermediate" in MCE Product Catalog:

7
Acetyl coenzyme A lithium
Acetyl coenzyme A lithium
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7 Cited Publications
Cat. No.: HY-113596A
CAS No.: 32140-51-5
Purity:  97%
Synonyms: Acetyl-CoA lithium
Acetyl-coenzyme A (Acetyl-CoA) lithium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A lithium, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A lithium is also a key precursor of lipid synthesis .
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5
UDP-Galactose disodium
UDP-Galactose disodium
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5 Cited Publications
Cat. No.: HY-114364
CAS No.: 137868-52-1
Purity:  99.42%
Category:  

Natural Products Neurological Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite P2Y Receptor

UDP-Galactose disodium is a monosaccharide and a key glycosyl donor molecule in cells that participates in nucleotide sugar metabolism. UDP-Galactose disodium is the natural agonist of the P2Y14 receptor coupled to Gi proteins in the immune system (IC50 = 0.67 μM, hP2Y14). UDP-Galactose disodium can be used to study cell signal transduction and substance metabolism .
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5
Malic acid
Malic acid
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5 Cited Publications
Cat. No.: HY-Y1311
CAS No.: 6915-15-7
Synonyms: Hydroxybutanedioic acid; E 296
Category:  

Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Malus pumila Mill. Other Diseases Rosaceae Plants Endogenous metabolite Disease Research Fields

Target:  

Environmental Pollutants Endogenous Metabolite

Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that occurs naturally in fruits like apples and pears with oral activities. Malic acid plays a role in many sour or tangy foods. Malic acid is an intermediate in the citric acid cycle .
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5
Sulfanilamide
Sulfanilamide
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5 Cited Publications
Cat. No.: HY-B0242
CAS No.: 63-74-1
Synonyms: Sulphanilamide
Target:  

Environmental Pollutants Antibiotic Bacterial

Research Areas:  

Infection

ulfanilamide (Sulphanilamide) is a potent and orally active sulfonamide antibiotic and can be a major intermediate of sulfamethoxazole biodegradation. Sulfanilamide also is a carbonic anhydrase inhibitor. Sulfanilamide shows inhibition on virus of lymphogranuloma venereum .
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5
Citicoline
Citicoline
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5 Cited Publications
Cat. No.: HY-B0739
CAS No.: 987-78-0
Synonyms: Cytidine diphosphate-choline; CDP-Choline; Cytidine 5'-diphosphocholine
Category:  

Alkaloids Human Gut Microbiota Metabolites other families Microorganisms Animals Other Alkaloids Plants Endogenous metabolite

Target:  

Apoptosis Endogenous Metabolite Reactive Oxygen Species (ROS) Caspase

Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study .
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5
Citicoline sodium
Citicoline sodium
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5 Cited Publications
Cat. No.: HY-B0739A
CAS No.: 33818-15-4
Synonyms: Cytidine diphosphate-choline sodium; CDP-Choline sodium; Cytidine 5'-diphosphocholine sodium
Category:  

Alkaloids other families Microorganisms Animals Other Alkaloids Plants Endogenous metabolite

Target:  

Endogenous Metabolite Apoptosis Reactive Oxygen Species (ROS) Caspase

Citicoline sodium is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline sodium inhibits reactive oxygen species (ROS) and apoptosis. Citicoline sodium can be used for neurological disease and hearing loss study .
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5
Kinsenoside
Kinsenoside
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5 Cited Publications
Cat. No.: HY-N2292
CAS No.: 151870-74-5
Category:  

Natural Products Orchidaceae Plants Anoectochilus Disease Research Fields Inflammation/Immunology

Target:  

Keap1-Nrf2 Apoptosis

Kinsenoside is the main active ingredient of the genus plant, and has various biological activities. Kinsenoside and Nrf2 depend on the protection of nuclear cells (NPCs), which significantly reduces their ability to survive. Kinsenoside Active NPC Medium AKT-ERK1/2-Nrf2 Signal passage, Prevent physical decline, aging, harmonious physical function impairment. Kinsenoside can improve the puncture guide model for intermediate vertebral wall discharge (IDD).
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5
Succinyl-Coenzyme A sodium
Succinyl-Coenzyme A sodium
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5 Cited Publications
Cat. No.: HY-137808
CAS No.: 108347-97-3
Purity:  94%
Synonyms: Succinyl-CoA sodium
Category:  

Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Succinyl CoA (Succinyl-coenzyme A) sodium is a pivotal intermediate metabolite in the tricarboxylic acid cycle and a key coenzyme A metabolite. Succinyl CoA sodium is biosynthesized from α-ketoglutarate or propionyl-CoA. Succinyl CoA sodium acts as a critical precursor and substrate for heme biosynthesis and gluconeogenesis. Succinyl CoA sodium insufficiency caused by cobalamin deficiency is directly linked to growth retardation, impaired heme synthesis, tissue glycine accumulation and neurological abnormalities. Succinyl CoA sodium can be used in research on metabolic, neurological, and hematological abnormalities (such as porphyria) caused by nutritional vitamin B12 deficiency (leading to a lack of Succinyl-Coenzyme A synthesis) .
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4
Lanosterol
Lanosterol
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4 Cited Publications
Cat. No.: HY-W020033
CAS No.: 79-63-0
Category:  

Triterpenes Human Gut Microbiota Metabolites Terpenoids Endogenous metabolite

Target:  

Endogenous Metabolite

Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol suppresses the aggregation and cytotoxicity of misfolded proteins linked with neurodegenerative diseases .
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4
L-Dihydroorotic acid
L-Dihydroorotic acid
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4 Cited Publications
Cat. No.: HY-W015495
CAS No.: 5988-19-2
Category:  

Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite Dihydroorotate Dehydrogenase

L-Dihydroorotic acid is an important intermediate in the metabolism of orotic acid and a substrate of dihydroorotate dehydrogenase (DHODH). L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme .
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4
SAICAR
SAICAR
0 Images
4 Cited Publications
Cat. No.: HY-126585
CAS No.: 3031-95-6
Purity:  99.57%
Category:  

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer

Target:  

Endogenous Metabolite

SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner, with an EC50 of 0.3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose-limited conditions .
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4
Fumaric acid
Fumaric acid
0 Images
4 Cited Publications
Cat. No.: HY-W015883
CAS No.: 110-17-8
Category:  

Metabolic Disease Endocrine diseases Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Cancer

Target:  

Environmental Pollutants Endogenous Metabolite NF-κB p38 MAPK

Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension .
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4
Fumaric acid disodium
Fumaric acid disodium
0 Images
4 Cited Publications
Cat. No.: HY-W015883A
CAS No.: 17013-01-3
Category:  

Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite NF-κB p38 MAPK

Fumaric acid disodium is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid disodium exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid disodium can be used in the study of pregnancy-induced hypertension .
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4
Disodium succinate hexahydrate
Disodium succinate hexahydrate
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4 Cited Publications
Cat. No.: HY-W094516
CAS No.: 6106-21-4
Synonyms: Wormwood acid disodium hexahydrate
Disodium succinate hexahydrate (Wormwood acid disodium hexahydrate) is an anti-anxiety agent with oral activity. Disodium succinate hexahydrate is an intermediate product of the tricarboxylic acid cycle. Disodium succinate hexahydrate is an important platform chemical. Disodium succinate hexahydrate can be used as surfactant, additive, ion chelating agent, flavoring agent and other applications in chemical, pharmaceutical and food fields .
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4
TRAF-STOP inhibitor 6877002
TRAF-STOP inhibitor 6877002
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4 Cited Publications
Cat. No.: HY-110247
CAS No.: 433249-94-6
Purity:  99.67%
Target:  

TNF Receptor NF-κB

Research Areas:  

Cardiovascular Disease Inflammation/Immunology

TRAF-STOP inhibitor 6877002 is a selective CD40-TRAF6 interaction inhibitor. TRAF-STOP inhibitor 6877002 exerts anti-atherosclerotic activity by blocking the CD40-TRAF6 signaling pathway, inhibiting classical monocyte activation, leukocyte recruitment, and macrophage activation and migration. TRAF-STOP inhibitor 6877002 reduces the phosphorylation levels of signaling intermediates in the canonical NF-κB pathway .
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3
Shikimic acid
Shikimic acid
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3 Cited Publications
Cat. No.: HY-N0130
CAS No.: 138-59-0
Category:  

Microorganisms Ketones, Aldehydes, Acids Other Diseases Plants Acacia confusa Merr. Compositae Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Shikimic acid is a key metabolic intermediate of the aromatic amino acid biosynthesis pathway, found in microbes and plants.
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3
Hypotaurine
Hypotaurine
0 Images
3 Cited Publications
Cat. No.: HY-100803
CAS No.: 300-84-5
Purity:  99.88%
Synonyms: 2-Aminoethanesulfinic acid
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Endogenous Metabolite

Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor. Antioxidant .
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3
Squalene
Squalene
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3 Cited Publications
Cat. No.: HY-N1214
CAS No.: 111-02-4
Synonyms: Super Squalene; trans-Squalene; AddaVax
Category:  

Cardiovascular Disease Triterpenes Plants Endogenous metabolite Human Gut Microbiota Metabolites other families Microorganisms Animals Terpenoids Disease Research Fields

Target:  

Endogenous Metabolite Reactive Oxygen Species (ROS) Fungal

Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .
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3
L-Pyroglutamic acid
L-Pyroglutamic acid
0 Images
3 Cited Publications
Cat. No.: HY-76082
CAS No.: 98-79-3
Category:  

Immune System Disorder Ketones, Aldehydes, Acids Other Diseases Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Cardiovascular System Disorder

Target:  

Endogenous Metabolite

L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE) .
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3
L-Pyroglutamic acid sodium
L-Pyroglutamic acid sodium
0 Images
3 Cited Publications
Cat. No.: HY-76082A
CAS No.: 28874-51-3
Category:  

Alkaloids Pyrrole Alkaloids Other Diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

L-Pyroglutamic acid sodium is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid sodium is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid sodium can be used as a biomarker for systemic lupus erythematosus (SLE) .
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