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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4991 Results for "
expression
" in MedChemExpress (MCE) Product Catalog:
Products (4991)
4991 Results for "expression" in MCE Product Catalog:
Cat. No.: HY-N3847
CAS No.: 38965-51-4
Synonyms: Eriodictyol 7-O-β-D-glucoside
Category:
Flavonoids Labiatae Flavonones Metabolic Disease Phenols Polyphenols Plants Disease Research Fields Petalostemun purpureum
Target:
Cat. No.: HY-N4031
CAS No.: 82375-29-9
Cat. No.: HY-N5048
CAS No.: 122965-41-7
Synonyms: 6'-O-Galloyl paeoniflorin
Cat. No.: HY-N6928
CAS No.: 88901-37-5
Cat. No.: HY-N7700
CAS No.: 15769-56-9
Synonyms: G2013
Target:
Research Areas:
Guluronic acid (G2013) is an orally active oxidative stress regulator and anti-inflammatory agent that exerts pharmacological effects by down-regulating various pro-inflammatory and oxidative stress-related genes (such as TLR4, NF-κB, iNOS, etc.) and inhibiting the activities of COX-2, MMPs and VEGF. Low-dose Guluronic acid up-regulates the expression of immunoregulatory genes SHIP1 and SOCS1, thereby effectively inhibiting cancer-related inflammation, tumor angiogenesis, cell adhesion and metastasis, while reducing the accumulation of immunosuppressive cells. Guluronic acid significantly prolongs the survival time of tumor-bearing hosts within a concentration range without direct cytotoxicity, demonstrating favorable safety. Guluronic acid has involved in the research of multiple sclerosis, ankylosing spondylitis, breast cancer and other inflammatory diseases .
Cat. No.: HY-N9602
CAS No.: 189689-31-4
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Cat. No.: HY-P11291A
Target:
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Cat. No.: HY-P11298
CAS No.: 2120397-85-3
Research Areas:
Cat. No.: HY-P12141
CAS No.: 2227651-65-0
Synonyms: KP405
Target:
Research Areas:
DA5-CH (KP405) is a blood-brain barrier-permeable GLP-1/GIP receptor agonist. DA5-CH activates GLP-1 and GIP receptors, inhibits the NF-κB inflammatory pathway, reduces α-synuclein (α-synuclein) levels, restores the expression of tyrosine hydroxylase and neurotrophic factors, improves motor function, decreases amyloid plaques and phosphorylated tau protein levels in the hippocampus, restores synaptic plasticity, regulates the PI3K/AKT/GSK3β and CREB signaling pathways, and alleviates mitochondrial stress. DA5-CH can be used for research on Parkinson's disease and Alzheimer's disease .
Cat. No.: HY-P1624S
Synonyms: ALX-0600-Ala(13C3,15N) sodium
Research Areas:
Cat. No.: HY-P1624S1
Synonyms: ALX-0600-Leu(13C6,15N) sodium
Research Areas:
Research Areas:
N-Acetylneuraminate lyase (CgNal) (Sialic acid aldolase (CgNal)) is a rate-limiting enzyme in bacteria metabolism that catalyzes the reversible aldol cleavage of sialic acid, and it regulates the overall metabolism of the bacterial sialic acid catabolic pathway. N-Acetylneuraminate lyase (CgNal) catalyzes the reversible condensation reaction of pyruvate and N-acetyl-d-mannosamine (ManNAc) to produce sialic acid N-acetylneuraminic acid (Neu5Ac). The protein expression of N-Acetylneuraminate lyase is downregulated at the translational level under the regulation of methyl methanesulfonate, and this change significantly impairs the adhesion and invasion abilities of bacteria to eukaryotic cells. N-Acetylneuraminate lyase is a key virulence-related protein in various pathogenic bacteria and is considered an antibiotic drug target. N-Acetylneuraminate lyase (CgNal) can be used in studies of invasive (extraintestinal) infectious diseases, Crohn's disease, and methicillin-resistant Staphylococcus aureus infections .
Cat. No.: HY-P990160
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
Cat. No.: HY-P991097
Synonyms: PM-8002; BNT-327
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Cat. No.: HY-P991842
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Cat. No.: HY-P992519
Synonyms: ADWA-11
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Cat. No.: HY-P99759
CAS No.: 1622189-43-8
Synonyms: IL-15N72D
Target:
Research Areas:
Cat. No.: HY-W009141R
CAS No.: 542-44-9
Synonyms: Glyceryl palmitate (Standard)
Category:
Cat. No.: HY-W009141S
Synonyms: Glyceryl palmitate-d31
Cat. No.: HY-W012382R
CAS No.: 537-55-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
