664 Results for "

ACT

" in MedChemExpress (MCE) Product Catalog:
Products (664)

664 Results for "ACT" in MCE Product Catalog:

2
2 Cited Publications
Art. -Nr.: HY-D0227B
CAS. Nr.: 6850-28-8
Synonyms: Tris acetate; Tris(hydroxymethyl)aminomethane acetate
Forschungsgebiete:  

Metabolic Disease

THAM acetate is a low-toxicity amino alcohol buffer, a CO2-consuming proton acceptor that buffers carbon dioxide and acid both in vitro and in vivo. THAM acetate binds protons to form bicarbonate, reduces PaCO2, and induces intracellular alkalization, thereby ameliorating hypercapnia-induced elevation of pulmonary blood vessels and pulmonary arterial pressure. THAM acetate may cause PaCO2 rebound, hypoglycemia, and respiratory depression. THAM acetate removes amniotic epithelium and preserves the basement membrane, but depletes extracellular matrix and reduces the adhesion rate of limbal epithelial cells. THAM acetate can act as a CO2 carrier to enhance the productivity and carbon utilization rate of Scenedesmus obliquus. THAM acetate is a key component of buffer solutions used in various biological, cell culture, biochemical, and molecular biology applications .
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2
2 Cited Publications
Art. -Nr.: HY-D0227J
CAS. Nr.: 1185-53-1
Synonyms: Tris HCl (≥99%, for cell culture); Tris hydrochloride (≥99%, for cell culture)
THAM hydrochloride (≥99%, for cell culture) is a low-toxicity amino alcohol buffer, a specific CO2-consuming proton acceptor that buffers carbon dioxide and acid both in vitro and in vivo. THAM hydrochloride (≥99%, for cell culture) binds protons to form bicarbonate, reduces PaCO2, and induces intracellular alkalization, thereby ameliorating hypercapnia-induced elevation of pulmonary blood vessels and pulmonary arterial pressure. THAM hydrochloride (≥99%, for cell culture) may cause PaCO2 rebound, hypoglycemia, and respiratory depression. THAM hydrochloride (≥99%, for cell culture) removes amniotic epithelium and preserves the basement membrane, but depletes extracellular matrix and reduces the adhesion rate of limbal epithelial cells. THAM hydrochloride (≥99%, for cell culture) can act as a CO2 carrier to enhance the productivity and carbon utilization rate of Scenedesmus obliquus. THAM hydrochloride (≥99%, for cell culture) is a key component of buffer solutions used in various biological, cell culture, biochemical, and molecular biology applications .
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1
1 Cited Publications
Art. -Nr.: HY-79593
CAS. Nr.: 475085-57-5
Synonyms: ACT-333679
Forschungsgebiete:  

Cardiovascular Disease Endocrinology

MRE-269 is an active metabolite of selexipag, and acts as a selective IP receptor agonist.
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1
1 Cited Publications
Art. -Nr.: HY-B1896B
CAS. Nr.: 915967-82-7
Target:  

Parasite

Forschungsgebiete:  

Infection

Piperaquine tetraphosphate tetrahydrate is a bisquinoline antimalarial agent. Piperaquine tetraphosphate tetrahydrate can be used in antimalarial research in combination with Artemisinin .
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1
1 Cited Publications
Art. -Nr.: HY-B1896A
CAS. Nr.: 85547-56-4
Target:  

Parasite

Forschungsgebiete:  

Infection

Piperaquine phosphate is a bisquinoline antimalarial agent. Piperaquine phosphate can be used in antimalarial research in combination with Artemisinin .
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1
1 Cited Publications
Art. -Nr.: HY-111817
CAS. Nr.: 1984890-99-4
Reinheit:  96.45%
Target:  

Parasite

Forschungsgebiete:  

Infection

ACT-451840 is an orally active, potent and low-toxicity compound, showing activity against sensitive and resistant plasmodium falciparum strains. ACT-451840 targets all asexual blood stages of the parasite, has a rapid onset of action. ACT-451840 behaves in a way similar to artemisinin derivatives, with very rapid onset of action and elimination of parasite. ACT-451840 can be used for the research of malarial .
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1
1 Cited Publications
Art. -Nr.: HY-P73412
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SERPINA3; Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3, Isoform CRA_a; Prev. AACT; Growth-Inhibiting Protein 24; ACT; Growth-Inhibiting Protein 25; Alpha-1-Antichymotrypsin; Alpha-1 Antichymotrypsin; Serpin Peptidase
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Art. -Nr.: HY-W015878
CAS. Nr.: 660-88-8
5-Aminovaleric acid is believed to act as a methylene homologue of gamma-aminobutyric acid (GABA) and functions as a weak GABA agonist.
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1
1 Cited Publications
Art. -Nr.: HY-121584
CAS. Nr.: 42438-90-4
Reinheit:  99.82%
Synonyms: Cyclomethyltryptophan
Lycoperodine-1 (Cyclomethyltryptophan) is an active product that can be isolated from tomato fruits (Lycopersicon sculentum). Lycoperodine-1 act as an agonist of Ca 2+ sensing receptors (CaSR) .
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1
1 Cited Publications
Art. -Nr.: HY-41494
CAS. Nr.: 118-90-1
Synonyms: 2-Methylbenzoic acid
O-toluic acid (2-Methylbenzoic acid) is an organic compound that is benzoic acid with a methyl group substituted at the 2-position. O-toluic acid can act as an exogenous metabolite and holds some chemical research value .
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1
1 Cited Publications
Art. -Nr.: HY-126861
CAS. Nr.: 137017-45-9
Reinheit:  99.70%
Forschungsgebiete:  

Others

2'-Deoxy-5-formylcytidine is an effective internal triplet photosensitizer in DNA. 2'-Deoxy-5-formylcytidine could act as a new hot spot in DNA photodamage .
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1
1 Cited Publications
Art. -Nr.: HY-A0213A
CAS. Nr.: 149845-07-8
Synonyms: Tiludronic acid disodium
Target:  

Proton Pump

Forschungsgebiete:  

Inflammation/Immunology

Tiludronate (Tiludronic Acid) disodium, an orally active bisphosphonate, can act an osteoregulator. Tiludronate is used for the research of the metabolic bone disorders. Tiludronate is a potent inhibitor of the osteoclast vacuolar H(+)-ATPase. Antiresorptive and anti-inflammatory properties .
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1
1 Cited Publications
Art. -Nr.: HY-N0216S
CAS. Nr.: 1079-02-3
Benzoic acid-d5 is a deuterium substitute for Benzoic acid. Benzoic acid is an aromatic alcohol that occurs naturally in many plants and is a common additive in food, beverages, cosmetics and other products. Benzoic acid can act as a preservative by inhibiting bacteria and fungi .
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1
1 Cited Publications
Art. -Nr.: HY-N4121
CAS. Nr.: 24063-71-6
Isocurcumenol, an estrogen receptor alpha (ERα) inhibitor isolated from Curcuma zedoaria Rhizomes, possesses anti-tumor acticity, with IC50 values of 99.1μg/mL and 178.2 μg/mL in DLA and KB cells, respectively .
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1
1 Cited Publications
Art. -Nr.: HY-18377
CAS. Nr.: 1420071-30-2
Synonyms: DR5 ACTivator
Target:  

TNF Receptor Apoptosis

Forschungsgebiete:  

Cancer

Bioymifi (DR5 Activator), a potent TRAIL receptor DR5 activator, binds to the extracellular domain (ECD) of DR5 with a Kd of 1.2 μM. Bioymifi can act as a single agent to induce DR5 clustering and aggregation, leading to apoptosis .
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1
1 Cited Publications
Art. -Nr.: HY-W004520
CAS. Nr.: 299-11-6
Synonyms: 5-Methylphenazinium methylsulfate
Forschungsgebiete:  

Cancer

Phenazine methylsulfate is a free radical generator that can act as an electron transfer reactant in cell viability assays. It also has insecticidal properties. Furthermore, Phenazine methylsulfate induces oxidative DNA damage and cell apoptosis, showing antitumor activity .
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1
1 Cited Publications
Art. -Nr.: HY-119751
CAS. Nr.: 475-25-2
Reinheit:  65.25%
Forschungsgebiete:  

Cancer

Hematein is a oxidation product of hematoxylin acted as a dye . Hematein is an allosteric casein kinase II inhibitor with an IC50 of 0.74 μM. Hematein inhibits Akt/PKB Ser129 phosphorylation, the Wnt/TCF pathway and increases apoptosis in lung cancer cells .
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1
1 Cited Publications
Art. -Nr.: HY-B1162
CAS. Nr.: 4065-45-6
Synonyms: Benzophenone-4
Sulisobenzone (Benzophenone-4) is a benzophenone-type UV filter. Sulisobenzone can act as a endocrine disrupting compound. Sulisobenzone disrupts energy metabolism, nucleotide synthesis, oxidative stress response, and endocrine function. Sulisobenzone thyroid hormone biosynthesis and induces oxidative stress .
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1
1 Cited Publications
Art. -Nr.: HY-P78189
Reinheit:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF4; CD134 Antigen; Prev. TXGP1L; Tumor Necrosis FACTor Receptor Superfamily, Member 4; Tumor Necrosis FACTor Receptor Superfamily Member 4; Lymphoid ACTivation Antigene ACT35; OX40L Receptor; OX40 Cell Surface Antigen; ACT35; OX40 Homologue; CD134; A
Species:  
Human
Source:  
HEK293
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