393 Results for "

grid-walking test

" in MedChemExpress (MCE) Product Catalog:
Products (393)

393 Results for "grid-walking test" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N7694
CAS No.: 97871-44-8
Isotoosendanin is an orally active TGFβR1 inhibitor and abrogating its kinase activity (IC50 = 6732 nM). Isotoosendanin inhibits the JAK/STAT3 signaling pathway by directly targeting SHP-2, enhancing its stability, and reducing its ubiquitination. Isotoosendanin inhibits TGF-β-induced reduces the migration, invasion, and metastasis in triple-negative breast cancer (TNBC) cells. Isotoosendanin exhibits anti-tumor efficacy in TNBC xenograft models and A549 xenograft tumors. Isotoosendanin exhibits significant anti-inflammatory effects in acetic acid-induced vascular permeability and λ-carrageenan-induced hind paw edema tests. Isotoosendanin can be used for the study of non-small cell lung cancer (NSCLC), TNBC and inflammation .
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1 Cited Publications
Cat. No.: HY-Y0678
CAS No.: 621-23-8
Synonyms: TRIMETHYL PHLOROGLUCINOL
1,3,5-Trimethoxybenzene (TRIMETHYL PHLOROGLUCINOL) is an electrophilic substitution reaction substrate targeting free chlorine (Cl +) and free bromine (Br +). 1,3,5-Trimethoxybenzene has highly selective electrophilic addition characteristics. By capturing halogens, it undergoes specific substitution reactions to generate stable halogenated products. 1,3,5-Trimethoxybenzene can not only quench residual oxidants, but also quantify the halogen concentration by detecting the product without affecting the stability of redox-sensitive disinfection byproducts (DBPs). 1,3,5-Trimethoxybenzene is mainly used in water quality testing and quantitative analysis of free chlorine/bromine in water. At the same time, in phytochemistry, it is a key component of rose fragrance and participates in the study of pollination attraction mechanism .
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1 Cited Publications
Cat. No.: HY-W011927S
CAS No.: 2483831-28-1
Synonyms: Bisphenol S (4,4'-Sulfonyldiphenol)-d8
4,4'-Sulfonyldiphenol-d8 (Bisphenol S (4,4'-Sulfonyldiphenol)-d8) is the deuterium labeled 4,4'-Sulfonyldiphenol (HY-W011927).4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone), a substitute for Bisphenol A (HY-18260), is widely used in industrial and consumer products. 4,4'-Sulfonyldiphenol is an estrogen receptor (ER) agonist and can competitively bind to thyroid hormone receptors (TR) with IC50 values for TRα and TRβ are 2650 μM and 2294 μM respectively, thereby affecting breast development and reducing the expression of androgen receptor (AR) in fetal testes. 4,4'-Sulfonyldiphenol promotes the progression of glioblastoma by upregulating the EZH2 mediated PI3K/AKT/mTOR pathway. Under chronic exposure, 4,4'-Sulfonyldiphenol can cause significant lipid deposition and dyslipidemia in the mouse liver by upregulating JunB and Atf3, and has a role in causing obesity at low doses. 4,4'-Sulfonyldiphenol induces intestinal inflammation by altering the intestinal microbiome. 4,4'-Sulfonyldiphenol accelerates the progression of atherosclerosis in zebrafish embryo larvae.
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Cat. No.: HY-W134423
CAS No.: 9002-18-0
Agar, microbiology tested, for cell culture (powder) is a jelly like substance that contains agarose and agar gel. Agar, microbiology tested, for cell culture (powder) can be isolated from the cell walls of red algae species such as Gelidium and Gracilaria (Ogonori). The gelation and melting of Agar, microbiology tested, for cell culture (powder) is based on the hydrogen bridge (physical gels), so the gelation is reversible. Agar, microbiology tested, for cell culture (powder) is widely used in food additives, plant tissue culture, microorganisms culture media, fingerprint recognition, and medical fields .
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Cat. No.: HY-Z0275
CAS No.: 39968-33-7
Research Areas:  

Infection

HOAT is a peptide bond-forming reagent. HOAT is utilized to affect formation of peptide bonds by coupling carboxylic acids with amines. HOAt is not mutagenic in the bacterial reverse mutation test .
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Cat. No.: HY-172445
CAS No.: 438545-06-3
Synonyms: SS-DNA
Deoxyribonucleic acid sodium salt from salmon testes (SS-DNA) is a double-stranded deoxyribonucleic acid sodium salt extracted from salmon testes, which serves as an anti-adhesion agent and surface passivating agent for the surface of gold plasmonic sensors. Deoxyribonucleic acid sodium salt from salmon testes forms a nanoscale-thick film on the surface of gold plasmonic sensors, preventing non-specific adsorption of subsequent DNA analyte layers .
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Cat. No.: HY-D0867
CAS No.: 10191-18-1
BES is a secondary standard biochemical buffer with effective pH range of 6.4 to 7.8 (pKa: 7.15 at 20 °C). BES is used in the diagnostic testing area.
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Cat. No.: HY-W039938
CAS No.: 2001-96-9
Target:  

Fluorescent Dye

Research Areas:  

Others

4-Nitrophenyl β-D-xylopyranoside is a chromogenic β-xylosidase substrate. 4-Nitrophenyl β-D-xylopyranoside can be used to test β-xylosidase activity .
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Cat. No.: HY-15918
CAS No.: 82692-88-4
HDAOS is a novel Trinder's reagent, which is a highly water-soluble aniline derivative. HDAOS is widely used in diagnostic tests and biochemical tests .
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Cat. No.: HY-B1493
CAS No.: 37106-97-1
Target:  

Inhibitory Antibodies

Research Areas:  

Endocrinology

Bentiromide is a peptide that is broken down in the pancreas by chymotrypsin. The bentiromide test is an excellent means of confirming the diagnosis of pancreatic exocrine insufficiency by outpatient test of chymotrypsin function .
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Cat. No.: HY-W134423A
CAS No.: 9002-18-0
Agar, microbiology tested, for cell culture (granular) is a hydrocolloid with gelling ability. Agar, microbiology tested, for cell culture (granular) can be used to prepare microbial culture media (for bacteria, yeasts and molds) .
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Cat. No.: HY-W127350
CAS No.: 1182-66-7
Target:  

Liposome

Research Areas:  

Metabolic Disease

Cholesterol Pelargonate, a Cholesterol derivative, can be used as a triggered release liposome tested .
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Cat. No.: HY-W134423B
CAS No.: 9002-18-0
Agar, meets USP testing specifications is a high-quality selective growth support and substrate for non-adherent cells. Agar, meets USP testing specifications effectively supports the growth, colony formation and metachromatic matrix production of chondrocytes, and also facilitates the isolation and differentiation of pure chondrocyte strains by restricting the proliferation of fibroblast-like cells. Chondrocytes grown in Agar, meets USP testing specifications can be successfully transferred to a liquid suspension culture system, where they continue to proliferate while retaining the characteristics exhibited during growth in agar .
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Cat. No.: HY-137367
CAS No.: 124485-41-2
Purity:  99.77%
Target:  

Cathepsin

Research Areas:  

Infection

Z-Val-Val-Arg-AMC is a fluorescent peptide substrate that can be used to test the activity of cathepsins .
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Cat. No.: HY-P4460
CAS No.: 60354-61-2
Target:  

Ser/Thr Protease

Research Areas:  

Cancer

AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .
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Cat. No.: HY-P4453
CAS No.: 201732-83-4
Target:  

Caspase

Research Areas:  

Cancer

Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B .
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Cat. No.: HY-D0222
CAS No.: 86-56-6
N,N-Dimethyl-1-naphthylamine is an aromatic amine and a dye. N,N-Dimethyl-1-naphthylamine can be used in nitrate reduction test .
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Cat. No.: HY-B2243H
CAS No.: 7558-80-7
Synonyms: Sodium phosphate monobasic (USP); Monosodium dihydrogen orthophosphate (USP); Monosodium phosphate (USP)
Research Areas:  

Others

Anhydrous sodium dihydrogen phosphate, meets USP testing specifications is an inorganic salt. It is a chemical compound of sodium with a phosphate counter ion. Anhydrous sodium dihydrogen phosphate, meets USP testing specifications can be used as a pH buffer with other sodium phosphates .
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Cat. No.: HY-168535
CAS No.: 1010913-79-7
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

SJ6145 is a potent ligand for KLHDC2 SBD, with the Kd of 16.9 μM in SPR test, IC50 value of 42 μM in inhibiting KLHDC2 SBD binding to a di-Gly degron peptide test .
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Cat. No.: HY-P4455
CAS No.: 90037-94-8
Target:  

Bacterial

Research Areas:  

Infection

Boc-AAG-pNA is a glycine endopeptidase substrate. Boc-AAG-pNA can be used to test the amidase activity glycine endopeptidase .
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