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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
507 Results for "
hydroxyl
" in MedChemExpress (MCE) Product Catalog:
Products (507)
507 Results for "hydroxyl" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: O-Methylhydroxylamine hydrochloride; TRC-102 hydrochloride
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Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents .
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1
1 Cited Publications
Cat. No.: HY-DY1022
CAS No.: 217075-36-0
Solvent and concentration: DMSO: 2 mM
Synonyms: Polyoxyethylene lauryl ether; Polyoxyethyleneglycol Dodecyl Ether
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Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias.
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6’-Amino-D-luciferin is a derivative of D-luciferin (HY-12591A) with an amino group replacing the 6-hydroxyl group. 6’-Amino-D-luciferin is a natural substrate of luciferase (Luc) and can be used for IVIS imaging in cell/animal experiments[1][2][3].
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Isatoic anhydride is a single-adduct forming reagent and a monofunctional SHAPE reagent. Isatoic anhydride reacts with the 2'-hydroxyl group of RNA nucleotides via a single reactive group to form a single adduct, without forming cross-links between nucleotides. In SHAPE-JuMP experiments, Isatoic anhydride serves as a control reagent for single-adduct formation, which is used to distinguish true cross-links from single-adduct formation .
Cat. No.: HY-N6964
CAS No.: 143061-65-8
Synonyms: Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside
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Flavonols Flavonoids Ginkgoaceae Extract Metabolic Disease Phenols Polyphenols Ginkgo biloba L. Plants Disease Research Fields
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Cat. No.: HY-W004289
CAS No.: 7132-64-1
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Cat. No.: HY-P4280
CAS No.: 74863-12-0
Synonyms: H-Arg-Tyr-OH
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Cat. No.: HY-W460072
CAS No.: 86013-78-7
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tert-Butyl 7-hydroxyheptanoate is a linker with a hydroxyl group and a t-butyl ester. The hydroxyl group allows for further derivatization or replacement with many other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Cat. No.: HY-P2844
CAS No.: 37211-65-7
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Polynucleotide Kinase is a DNA repair enzyme. Polynucleotide Kinase possesses both a 5’-kinase activity that catalyzes the transfer of phosphate from ATP to a 5’-hydroxyl (OH) terminus and also a 3’-phosphatase activity that converts 3’-phosphate termini to 3’-OH termini .
Cat. No.: HY-145779A
Purity: 99.63%
Synonyms: H-γ-Glu-Met-OH TFA; γ-Glu-Met TFA
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DEPMPO is a phosphorus-substituted nitrone spin trap probe that can capture superoxide anions and hydroxyl radicals. DEPMPO forms stable spin adducts with hydroxyl, aryl, sulfite and superoxide radicals, and the formation of these adducts can be inhibited by catalase or superoxide dismutase. DEPMPO is rapidly absorbed after intraperitoneal injection and distributes uniformly in the liver, heart and blood of mice. DEPMPO can be used in studies related to oxygen radical detection .
Cat. No.: HY-161973
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Hydroxyl-ML-210 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). Hydroxyl-ML-210 can be used for synthesis ZX782 (HY-161972) .
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Hexamethoxymethylmelamine (Hexakis(methoxymethyl)melamine; HMMM) is a type of multifunctional melamine-formaldehyde crosslinker. Under acid-catalyzed conditions, Hexamethoxymethylmelamine enables chemical crosslinking between hydroxyl-functionalized polymers and hydroxyl groups in coating systems via methoxy-hydroxyl reactions, forming an interconnected network structure. Hexamethoxymethylmelamine can be used in organic synthesis-related research, such as thermosetting coatings .
Cat. No.: HY-176513
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Cy-OH-LP is a turn-on fluorescent and photoacoustic probe that can detect lipid-associated hydroxyl radicals. Cy-OH-LP can be oxidized to Cy7 in the presence of hydroxyl radicals, which displays weak fluorescent and photoacoustic signals in water-soluble environments and strong fluorescent and photoacoustic signals in lipid-rich environments due to its lipid solubility. Cy-OH-LP can be used for in vivo photoacoustic imaging of hydroxyl radicals .
Cat. No.: HY-W039729
CAS No.: 75178-90-4
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5-(Boc-amino)-1-pentanol is a linker containing a hydroxyl group and Boc-protected amino group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Cat. No.: HY-174967C
Cat. No.: HY-P4755
CAS No.: 282726-24-3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
