10415 Results for "

sulfonated ring products

" in MedChemExpress (MCE) Product Catalog:
Products (10415)

10415 Results for "sulfonated ring products" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-106024B
CAS No.: 341028-37-3
Purity:  99.82%
Synonyms: ALT711
Alagebrium chloride (ALT711) is an advanced glycation end product (AGE) inhibitor.
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6
6 Cited Publications
Cat. No.: HY-B1745
CAS No.: 85-87-0
Pyridoxylamine is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions.
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6
6 Cited Publications
Cat. No.: HY-B1745A
CAS No.: 524-36-7
Pyridoxylamine dihydrochloride is an advanced glycation end production (AGEs) and lipoxidation end products (ALEs) inhibitor, to protect against diabetes-induced retinal vascular lesions .
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6
6 Cited Publications
Cat. No.: HY-N2335
CAS No.: 479-13-0
Coumestrol, a phytoestrogen present in soybean products, exhibits activities against cancers, neurological disorders, and autoimmune diseases. It suppresses proliferation of ES2 cells with an IC50 of 50 μM.
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6
6 Cited Publications
Cat. No.: HY-D0185
CAS No.: 312693-72-4
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and 2'-deoxyribose, and it is one of the basic structural units of DNA. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which in turn may affect gene expression or induce cancer .
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5
5 Cited Publications
Cat. No.: HY-113329
CAS No.: 543-18-0
Purity:  ≥98.0%
Synonyms: Taurocyamine
Guanidinoethyl sulfonate (Taurocyamine) is an orally available, blood-brain permeable competitive inhibitor of taurine transporters and a competitive antagonist of glycine receptors (GlyR) (IC50=565 μM). Guanidinoethyl sulfonate has both weak agonist and antagonist effects on GABAA receptors. Guanidinoethyl sulfonate inhibits taurine transmembrane transport and competitively binds to the GlyR ligand binding domain, thereby blocking glycine-mediated chloride influx, and may regulate brain pH to exert neuroprotective effects. Guanidinoethyl sulfonate can be used for neuroprotection studies of ischemic brain injury .
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5
5 Cited Publications
Cat. No.: HY-A0062
CAS No.: 191114-48-4
Synonyms: HMR3647; RU66647
Target:  

Bacterial Antibiotic

Research Areas:  

Infection Inflammation/Immunology

Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma .
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5
5 Cited Publications
Cat. No.: HY-103006
CAS No.: 1612756-29-2
Purity:  99.93%
Research Areas:  

Others

NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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5
5 Cited Publications
Cat. No.: HY-166096
CAS No.: 18175-45-6
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Elaidic acid (sodium) is an ester product.
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5
5 Cited Publications
Cat. No.: HY-N0259
CAS No.: 110623-73-9
Synonyms: Epmedin B
Epimedin B (Epmedin B) is a flavonoid active component found in Epimedium, with oral activity, and exhibits anti-osteoporotic and neuroprotective effects. Epimedin B inhibits RANKL-induced osteoclast differentiation, F-actin ring formation, and mature osteoclast bone resorption, inhibits the phosphorylation of JNK, p38 MAPK, PI3K, and AKT, activates the AMPK-Nrf2 antioxidant pathway, and reduces cellular and mitochondrial ROS. Epimedin B acts on ESR1 and exerts its effects via GPER. Epimedin B alleviates bone loss and improves bone microstructure in vivo, and in Parkinson's models protects dopaminergic neurons and maintains striatal dopamine levels through anti-apoptotic and anti-endoplasmic reticulum stress effects. Epimedin B can be used for research related to osteoporosis, diabetic osteoporosis, and Parkinson's disease .
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5
5 Cited Publications
Cat. No.: HY-NP003
CAS No.: 9007-34-5
Synonyms: Collagen
Collagen, Type II, from bovine snout membrane is a type II collagen that can be used for cell culture . This product is enzymatically hydrolyzed collagen peptides.
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5
5 Cited Publications
Cat. No.: HY-125731
CAS No.: 360-65-6
Purity:  99.08%
Glycodeoxycholic Acid is a natural product found in Streptomyces nigricans, Trypanosoma brucei and C. elegans. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis .
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5
5 Cited Publications
Cat. No.: HY-15464D
CAS No.: 1189561-66-7
Purity:  98.39%
Synonyms: (S)-(+)-Gossypol acetic acid
Target:  

Bcl-2 Family

Research Areas:  

Cancer

(S)-Gossypol is the isomer of a natural product Gossypol. (S)-Gossypol binds to the BH3-binding groove of Bcl-xL and Bcl-2 proteins with high affinity.
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5
5 Cited Publications
Cat. No.: HY-N0212
CAS No.: 23496-41-5
Synonyms: Verticine; Dihydroisoimperialine
Peimine (Verticine; Dihydroisoimperialine) is an orally active natural product. Peimine has anti-inflammatory, analgesic and cough relieving effects. Peimine can be used in cancer and inflammation related research .
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4
4 Cited Publications
Cat. No.: HY-W583749
CAS No.: 73606-19-6
Synonyms: F-53B
Research Areas:  

Endocrinology

6:2 Cl-PFAES is an orally effective alternative to Perfluorooctane sulfonate. 6:2 Cl-PFAES significantly inhibits the growth of zebrafish and induces reproductive toxicity. 6:2 Cl-PFAES reduces the relative weights of epididymis and testis in male BALB/c mice. 6:2 Cl-PFAES can be used in the chrome plating industry .
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4
4 Cited Publications
Cat. No.: HY-B0359
CAS No.: 73151-29-8
Synonyms: REC 15-1476
Target:  

Fungal Antibiotic

Research Areas:  

Infection

Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis .
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4
4 Cited Publications
Cat. No.: HY-120821
CAS No.: 1839524-44-5
Purity:  99.17%
Synonyms: ES2
Target:  

Exosomes

Research Areas:  

Others

Endosidin-2 (ES2) is a selective inhibitor targeting the conserved exosome subunit EXO70. Endosidin-2 binds to the C-terminal domain of EXO70, inhibiting exocytosis and endosomal recycling, while promoting vacuolar trafficking in plant cells. Endosidin-2 interferes with the EXO70-mediated vesicle-to-plasma membrane anchoring process, leading to abnormal aggregation of auxin transporters (such as PIN2) in the cytoplasm and redirected to vacuolar degradation, while causing abnormal Golgi structure (such as cup-shaped or ring-shaped vesicles cisternae formation). Endosidin-2 can inhibit exocytosis in plant and mammalian cells and is mainly used to study the dynamic regulation of membrane trafficking (such as polar growth, vesicle sorting) .
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4
4 Cited Publications
Cat. No.: HY-B0923
CAS No.: 117-10-2
Synonyms: Dantron; Chrysazin; 1,8-Dihydroxyanthraquinone
Danthron is a natural product extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge. Danthron functions in regulating glucose and lipid metabolism by activating AMPK.
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4
4 Cited Publications
Cat. No.: HY-122131
CAS No.: 111072-31-2
Purity:  99.90%
Research Areas:  

Others

XTT (sodium) is used to assess cell viability as a function of redox potential. Actively respiring cells convert the water-soluble XTT to a water-soluble, orange colored formazan product.
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4
4 Cited Publications
Cat. No.: HY-B1207
CAS No.: 51-79-6
Synonyms: Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane
Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial, protozoal, sea urchin egg, and plant tissue growth in vitro .
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