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  2. Peimine

Peimine (Synonyms: Verticine; Dihydroisoimperialine)

Cat. No.: HY-N0212 Purity: ≥98.0%
Handling Instructions

Peimine(Dihydroisoimperialine; Verticine) is a natural compound with good anti-inflammatory effects in vivo.

For research use only. We do not sell to patients.

Peimine Chemical Structure

Peimine Chemical Structure

CAS No. : 23496-41-5

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 86 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 86 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 78 In-stock
Estimated Time of Arrival: December 31
10 mg USD 126 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

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Description

Peimine(Dihydroisoimperialine; Verticine) is a natural compound with good anti-inflammatory effects in vivo. IC50 value: Target: Peimine (0-25 mg/L) significantly inhibited tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-1β, and increased IL-10 production. Furthermore, peimine significantly inhibited the phosphorylation of p38, ERK and c-jun N-terminal kinase (JNK) as well as decreased p65 and IκB.

Molecular Weight

431.65

Formula

C₂₇H₄₅NO₃

CAS No.
SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (115.83 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3167 mL 11.5835 mL 23.1669 mL
5 mM 0.4633 mL 2.3167 mL 4.6334 mL
10 mM 0.2317 mL 1.1583 mL 2.3167 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.79 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: ≥98.0%

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Keywords:

PeimineVerticine DihydroisoimperialineOthersInhibitorinhibitorinhibit

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Product Name:
Peimine
Cat. No.:
HY-N0212
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