396 Results for "

Fluorescence Probe

" in MedChemExpress (MCE) Product Catalog:
Products (396)

396 Results for "Fluorescence Probe" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-133705
CAS No.: 2969156-01-0
Purity:  98.43%
Geldanamycin-FITC, a Geldanamycin fluorescent probe, can be used in a fluorescence polarization assay for HSP90 inhibitors. Geldanamycin-FITC also can be used for detection of cell surface HSP90 (Ex/Em = 488/515 nm) .
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1 Cited Publications
Cat. No.: HY-151644
CAS No.: 78044-20-9
Purity:  98.90%
Fluorescein hydrazide is a sensitive fluorescent probe for Hg 2+ and Co 2+ that induces obvious color changes and fluorescence changes. Fluorescein hydrazide can be prepared by the reaction of fluorescein and hydrazine. Fluorescein hydrazide exhibits an excitation wavelength of 508 nM and an emission wavelength of 531 nM [2][3].
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1 Cited Publications
Cat. No.: HY-D1723
Target:  

DNA Stain

Research Areas:  

Others

EthD-III is a nucleic acid probe. EthD-III is a red fluorescent stain that can be used to detect dead cells. EthD-III enters cells with damaged membranes and binds to nucleic acids, resulting in bright red fluorescence in dead cells (Ex/Em=530/645 nm) .
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1 Cited Publications
Cat. No.: HY-D0988
CAS No.: 11016-17-4
Synonyms: R-PE
R-Phycoerythrin is found in Heterosiphonia japonica. R-Phycoerythrin is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex: 495 nm).
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1 Cited Publications
Cat. No.: HY-W089353
CAS No.: 194235-40-0
8-Phenyl-BODIPY 505/515 is a molecular rotor based on the BODIPY scaffold, specifically used as a microviscosity probe. The working principle of 8-Phenyl-BODIPY 505/515 is based on the restriction of molecular motion by viscosity: in a high-viscosity environment, the rotational freedom of its chemical bonds is inhibited, which leads to a significant extension of fluorescence lifetime. This property makes 8-Phenyl-BODIPY 505/515 an effective tool for monitoring changes in the viscosity of intracellular microenvironments via fluorescence lifetime imaging (FLIM) technology .
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1 Cited Publications
Cat. No.: HY-D1261
CAS No.: 210292-65-2
Synonyms: Thiol-green 1
Naph-EA-mal (Thiol-green 1) is a rapid detect and ultrafast turn-on thiol fluorescence probe for protein labeling and bioimaging. Naph-EA-mal (Thiol-green 1) can be used to detect thiols in living cells, label the protein thiols, quantify the concentration of total thiols in cell lysate, and determine the reversible protein thiols oxidation in fixed cells . Ex: 488 nM; Em: 540 nM.
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1 Cited Publications
Cat. No.: HY-W010042
CAS No.: 921-60-8
Synonyms: L-(-)-Glucose
Target:  

Fluorescent Dye

Research Areas:  

Metabolic Disease Cancer

L-Glucose (L-(-)-Glucose) is a stereoisomer of D-Glucose (HY-B0389), which does not readily enter the brain. L-Glucose can promote food intake. L-glucose is combined with a fluorescence detector to produce a fluorescent probe that can be used to visualize and characterize cancer cells. L-Glucose also can be used in the research to enhance memory in mice .
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1 Cited Publications
Cat. No.: HY-D1428
CAS No.: 797785-10-5
Di-4-ANEPPDHQ is a polarity-sensitive membrane probe with a doubly positive charge that can be used to visualize membrane microdomains in living Arabidopsis cells. Di-4-ANEPPDHQ produces a fluorescence spectrum shift by changing the polarity of the lipid environment after embedding into the cell membrane, thereby quantifying the degree of lipid accumulation. The excitation wavelength of Di-4-ANEPPDHQ is 488 nm, and the emission wavelengths are 560 nm and 650 nm in the liquid ordered and disordered phases, respectively. Di-4-ANEPPDHQ is often used for fluorescence imaging studies of membrane microstructure, lipid order, and membrane tension response in living cells[1][2][3].
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1 Cited Publications
Cat. No.: HY-D1423
CAS No.: 68654-25-1
Target:  

Fluorescent Dye

Research Areas:  

Others

Dibromobimane is a Fluorescent dye and probe that can be used for the detection of intracellular reduced glutathione and the analysis of spatial proximity of closely adjacent cysteine thiol groups. Dibromobimane activates fluorescence through binding to thiol groups; its excitation/emission wavelengths are Ex/Em = 393/477 nm for glutathione detection, and Ex/Em = 385/477 nm for cysteine thiol cross-linking. Dibromobimane uses two equivalent bromomethyl groups to cross-link cysteine thiolates with a distance ranging from 3-6 Å. Dibromobimane can be applied to 96-well microplate-based high-throughput assays for labeling intracellular glutathione, and its fluorescence signal is normalized against nuclear staining results to eliminate the impact of cell density .
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1 Cited Publications
Cat. No.: HY-P2031
CAS No.: 26645-35-2
Phallacidin is a natural bicyclic heptapeptide derived from the poisonous mushroom Amanita phalloides. Phallacidin binds to filamentous actin specifically with high affinity, with a Kd of 20 nM. After binding to F-actin, Phallacidin strongly inhibits its depolymerization, stabilizes microfilament structures, and prevents their disruption by drugs such as cytochalasins. When conjugated with a fluorophore, Phallacidin serves as a specific fluorescent probe for F-actin, which is used to clearly visualize the distribution of actin in the cytoskeleton (e.g., stress fibers, cortical peripheral bands) under fluorescence microscopy .
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1 Cited Publications
Cat. No.: HY-W007671
CAS No.: 1080-06-4
H-Tyr-OMe is an amino acid derivative and also a coordinating ligand for Cu II ions. H-Tyr-OMe can serve as a surface functionalization reagent for carbon dots, and is used to prepare fluorescent probes for biothiol sensing. H-Tyr-OMe is oxidized to quinone under the catalysis of Tyrosinase via its phenolic hydroxyl group, which quenches the fluorescence of carbon dots. H-Tyr-OMe contains potential coordination sites, including carboxyl, amino and phenolic hydroxyl groups .
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1 Cited Publications
Cat. No.: HY-W012228
CAS No.: 3417-91-2
Research Areas:  

Others

H-Tyr-OMe.HCl is an amino acid derivative and also a coordinating ligand for Cu II ions. H-Tyr-OMe.HCl can serve as a surface functionalization reagent for carbon dots, and is used to prepare fluorescent probes for biothiol sensing. H-Tyr-OMe.HCl is oxidized to quinone under the catalysis of Tyrosinase via its phenolic hydroxyl group, which quenches the fluorescence of carbon dots. H-Tyr-OMe.HCl contains potential coordination sites, including carboxyl, amino and phenolic hydroxyl groups .
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1 Cited Publications
Cat. No.: HY-W127703
CAS No.: 65603-19-2
Octadecyl Rhodamine B chloride is an amphiphilic fluorescent probe with both membrane-binding ability and fluorescent properties, which easily forms aggregates in aqueous phase leading to self-quenching. Octadecyl Rhodamine B chloride can be used for cell membrane staining and further applied in membrane biology research. The maximum absorption/emission wavelengths of Octadecyl Rhodamine B chloride monomer in Triton X-100 are 565 nm/585 nm; the absorption peaks of aggregates in water are blue-shifted to 524 nm and 574 nm, with significantly quenched fluorescence .
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1 Cited Publications
Cat. No.: HY-103609
CAS No.: 129-00-0
Purity:  99.72%
Synonyms: Benzo[def]phenanthrene
Pyrene is a polycyclic aromatic hydrocarbon (PAH) composed of four fused benzene rings. It has a distinct aromatic odor, produced by incomplete combustion of organic matter. Pyrene exhibits strong fluorescence, emitting in the blue region of the spectrum, making it useful as a probe for studying molecular interactions in solution and on surfaces. Pyrene is also used as a model compound for the study of PAHs in various environments and biological systems because of its ubiquity in these environments. However, long-term exposure to pyrene has been associated with potential health risks, including carcinogenicity and mutagenicity.
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1 Cited Publications
Cat. No.: HY-W250727
CAS No.: 53313-85-2
Synonyms: 6-(p-Tolylamino)naphthalene-2-sulfonate sodium
TNS (6-(p-Tolylamino) naphthalene-2-sulfonate) sodium is a fluorescent probe used to detect the conformational state of proteins. TNS sodium binds to the central hydrophobic calyx of β-lactoglobulin (β-LG) to form a 1:1 complex, which stabilizes the folded conformation of β-LG. TNS sodium shows weak fluorescent signals in aqueous solution, but its fluorescence intensity increases significantly upon binding to the hydrophobic domains of proteins, with the maximum excitation wavelength and maximum emission wavelength located at 321 nm and 446 nm, respectively .
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1 Cited Publications
Cat. No.: HY-W127716
CAS No.: 136724-73-7
Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can bu used as an effective quencher of quantum dots (QDs) fluorescence and the capture probe of virus antigen EV71. Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 can be used sensitive electrogenerated chemiluminescence (ECL) labels for detection of matrix metalloproteinases (MMPs) .
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1 Cited Publications
Cat. No.: HY-101898
CAS No.: 112926-02-0
Purity:  96%
Synonyms: Indo-1 Acetoxymethyl ester
Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues. MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions .
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Cat. No.: HY-W012642
CAS No.: 452-06-2
2-Aminopurine, a fluorescent analog of guanosine and adenosine, is a widely used fluorescence-decay-based probe of DNA structure. When 2-Aminopurine is inserted in anoligonucleotide, its fluorescence is highly quenched by stacking with the natural bases. 2-Aminopurine has been used to probe nucleic acid structure and dynamics .
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Cat. No.: HY-162543
CAS No.: 384833-00-5
Synonyms: 18:1 Lissamine rhodamine PE
Target:  

Fluorescent Dye

Research Areas:  

Others

18:1 Liss Rhod (18:1 Lissamine rhodamine) PE is a fluorescent phospholipid and fluorescent probe.18:1 Liss Rhod PE admixes into phospholipid inks for large-scale monitoring of dip-pen nanolithography-generated lithographic structures via fluorescence microscopy.18:1 Liss Rhod PE undergoes phase separation or self-quenching under certain conditions in thin lipid membrane stacks .
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Cat. No.: HY-129109
CAS No.: 1955505-54-0
Purity:  99.94%
NBD-Pen is the first fluorescence probe for lipid radicals with high selectivity and sensitivity (λex: 470 nm, λem: 530 nm). NBD-Pen specifically detects lipid derived radicals over other reactive species present in biological systems, including H2O2, ClO -, O2 -?, and ?OH. NBD-Pen directly detects lipid radicals in living cells by turn-on fluorescence. NBD-Pen decreases inflammation, apoptosis, and oxidative stress markers. NBD-Pen can be studied in various disease models such as hepatic carcinoma .
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