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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
912 Results for "
ring
" in MedChemExpress (MCE) Product Catalog:
Products (912)
912 Results for "ring" in MCE Product Catalog:
1
1 Cited Publications
Synonyms: Benzo[def]phenanthrene
1
1 Cited Publications
Target:
Research Areas:
TAMRA azide, 5-isomer is a click chemical containing azide groups that can be used as a linker for TAMRA. The azide group of TAMRA Azide, 5-isomer enables copper-catalyzed click chemical reactions with alkynes, DBCO, and BCN . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups (Ex/Em = 555/580 nm).
1
Category:
Natural Products Plants Other Families Extract Disease Research Fields Inflammation/Immunology
Target:
1
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Protocatechuate 3,4-dioxygenase is a dioxygenase. Protocatechuate 3,4-dioxygenase belongs to the non-heme iron dioxygenase class. Protocatechuate 3,4-dioxygenase catalyzes the cleavage of the aromatic ring of 3,4-dihydroxybenzoate, attaching two atoms of molecular oxygen to the compound to generate β-carboxy-cis,cis-muconate. Protocatechuate 3,4-dioxygenase is a key enzyme in the β-ketoadipic acid pathway. It is found in marine bacteria associated with Roseobacter. Protocatechuate 3,4-dioxygenase can be isolated from Pseudomonas aeruginosa .
1
1 Cited Publications
Cat. No.: HY-N0805A
CAS No.: 18649-93-9
Category:
Triterpenes Alisma plantago-aquatica Linn. Terpenoids Metabolic Disease Plants Disease Research Fields Alismataceae Extract
Target:
1
1
1 Cited Publications
Cat. No.: HY-P702076
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: RBCK1; Hepatitis B Virus X-Associated Protein 4; Prev. C20orf18; ring Finger Protein 54; UBCE7IP3; HOIL-1; RNF54; XAP3; XAP4; CDNA FLJ60704, Highly Similar To RanBP-Type And C3HC4-Type Zincfinger-Containing Protein 1; RanBP-Type And C3HC4-Type Zinc Finger
Species:
Human
Source:
E. coli
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RB-3, a polycomb repressive complex 1 (PRC1) inhibitor, binds to RING1B-BMI1f, with a Kd of 2.8 μM .
Cat. No.: HY-170823
CAS No.: 2396639-29-3
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PRC1-IN-1 is a PRC1 complex inhibitor. PRC1-IN-1 binds to both RING1A and RING1B proteins, and inhibits the activities of RING1B-BMI1 and RING1B-PCGF1. PRC1-IN-1 effectively inhibits H2AK119 ubiquitination and induces cell differentiation in leukemia cells. PRC1-IN-1 can be used for the research of leukemia .
Cat. No.: HY-W010610
CAS No.: 5239-82-7
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Research Areas:
2-Cyclopropylacetic acid is a substrate. 2-Cyclopropylacetic acid can produce a ring-opening product, which serves as an important precursor for the preparation of fused-ring molecules .
Cat. No.: HY-160924
Research Areas:
MS147 is a VHL-based PROTAC degrader of BMI1 and RING1B (polycomb repressive complex 1 core components). MS147 directly binds EED and VHL E3 ligase, recruiting the ligase to the EED-BMI1/RING1B complex to induce time-dependent, ubiquitination-mediated degradation of BMI1 and RING1B. MS147 reduces histone H2A Lys119 mono-ubiquitination without altering histone H3 Lys27 tri-methylation and inhibits cancer cells proliferation. MS147 can be used for the research of cancer, such as chronic myelogenous leukemia and b-cell lymphoma .
Category:
Ketones, Aldehydes, Acids Other Diseases Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields
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Cat. No.: HY-B0573S1
CAS No.: 344298-99-3
Cat. No.: HY-19555A
CAS No.: 148554-65-8
Synonyms: Secorapamycin A monosodium
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Research Areas:
Seco Rapamycin sodium salt is the ring-opened product of Rapamycin. Seco-rapamycin is reported not to affect the mTOR function.
Cat. No.: HY-N3200
CAS No.: 53734-74-0
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Synonyms: Ziprasidone Impurity C; Ziprasidone open ring impurity
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Research Areas:
Ziprasidone amino acid (Ziprasidone Impurity C) is an impurity of Ziprasidone. Ziprasidone is a combined 5-HT (serotonin) and dopamine receptor antagonist. Ziprasidone exhibits potent effects of antipsychotic activity .
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Cat. No.: HY-W265757
CAS No.: 1124-39-6
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Research Areas:
4-Ethylcatechol is a ring-dihydroxylated metabolite of 4-Ethylphenol that leads to oxidative DNA damage .
Cat. No.: HY-W015752
CAS No.: 2174-64-3
Target:
Cat. No.: HY-19555
CAS No.: 147438-27-5
Synonyms: Secorapamycin A
Target:
Research Areas:
Seco Rapamycin (Secorapamycin A) is the ring-opened product of Rapamycin. Seco-rapamycin is reported not to affect the mTOR function .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
