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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
379 Results for "
thrombin
" in MedChemExpress (MCE) Product Catalog:
Products (379)
379 Results for "thrombin" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-125864D
CAS No.: 9001-32-5
Target:
Research Areas:
Rabbit Fibrinogen is a native fibrinogen from rabbit plasma. Fibrinogen is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases .
2
2 Cited Publications
Cat. No.: HY-N1745A
CAS No.: 112408-67-0
1
1 Cited Publications
Cat. No.: HY-N8278
CAS No.: 54328-33-5
Target:
1
1 Cited Publications
Synonyms: S-2238 hydrochloride
1
1 Cited Publications
Synonyms: S-2238 acetate
1
1 Cited Publications
Cat. No.: HY-114164G
CAS No.: 9002-04-4
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Murine Thrombin is a murine serine protease that plays a central role in blood coagulation. Murine Thrombin stimulates macrophages to polarize into a unique phenotype characterized by anti-inflammatory and pro-repair properties. Murine Thrombin activates PAR1, induces the production of MCP-1, MMP3 and VEGF in mouse intervertebral discs, and causes degradation of the cartilage matrix and destruction of intervertebral disc structure. Murine Thrombin activity increases significantly in paraoxon-induced status epilepticus .
1
1 Cited Publications
Cat. No.: HY-17378
CAS No.: 429658-95-7
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Research Areas:
Dabigatran ethyl ester is an inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) and thrombin. Dabigatran ethyl ester inhibits NADH-dependent metabolism of mitomycin C mediated by purified recombinant human NQO2 .
1
1
1
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Research Areas:
Patamostat (E-3123) is a potent protease inhibitor. Patamostat potently inhibits trypsin, plasmin and thrombin with IC50s of 39 nM, 950 nM and 1.9 μM, respectively. Patamostat may possess suppressing effects on pathogenesis and development of acute pancreatitis .
1
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P1263A
CAS No.: 1262750-73-1
Synonyms: (trans-Cinnamoyl)-YPGKF-NH2 TFA
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P1741
CAS No.: 137235-80-4
Target:
Research Areas:
Fibrinogen-Binding Peptide is a Fibrinogen-binding peptide. Fibrinogen-Binding Peptide inhibits platelet adhesion to vitronectin and fibrinogen. Fibrinogen-Binding Peptide inhibits platelet aggregation in ADP-stimulated platelet-rich plasma and in thrombin-stimulated washed platelets. Fibrinogen-Binding Peptide can be used for research on thrombosis .
1
1 Cited Publications
Cat. No.: HY-P1741A
Target:
Research Areas:
Fibrinogen-Binding Peptide TFA is a Fibrinogen-binding peptide. Fibrinogen-Binding Peptide TFA inhibits platelet adhesion to vitronectin and fibrinogen. Fibrinogen-Binding Peptide TFA inhibits platelet aggregation in ADP-stimulated platelet-rich plasma and in thrombin-stimulated washed platelets. Fibrinogen-Binding Peptide TFA can be used for research on thrombosis .
1
1 Cited Publications
Cat. No.: HY-P701216
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: F2; Coagulation Factor II (thrombin); Coagulation Factor II, thrombin; Prothrombin B-Chain; Prothrombin; F2 Protein; Prepro-Coagulation Factor II; RPRGL2; Coagulation Factor II; THPH1; thrombin Factor II; PT
Species:
Human
Source:
HEK293
1
Target:
Research Areas:
Ximelagatran (H 376/95) is an orally active thrombin inhibitor that selectively and competitively inhibits both free and clot-bound thrombin. Ximelagatran is an anticoagulant agent with a rapid onset of anticoagulant effect, predictable, dose-dependent pharmcokinetics and pharmacodynamics .
1
1 Cited Publications
Cat. No.: HY-77521
CAS No.: 211914-50-0
Target:
Research Areas:
Dabigatran ethyl ester hydrochloride is a potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and a thrombin inhibitor.
1
1 Cited Publications
Cat. No.: HY-P99283
CAS No.: 1312299-39-0
Synonyms: NN 7415; mAb 2021; Anti-TFPI Recombinant Antibody
1
1 Cited Publications
Cat. No.: HY-163348
Research Areas:
FXIIa-IN-4 (compound 22) is a potent, selective human FXIIa inhibitor with the IC50 of 0.032 μM, 0.30 μM, ＞50 μM for FXIIa, thrombin and FXIa, respectively. FXIIa-IN-4 can be used for study of anticoagulant .
1
1 Cited Publications
Synonyms: 2-MeSAMP; 2-Methylthioadenosine 5′-monophosphate; 2-Methylthioadenosine 5′-phosphate
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Research Areas:
2-Methylthio-AMP (2-MeSAMP) is a selective and direct P2Y12 antagonist. 2-Methylthio-AMP is an inhibitor of ADP-dependent platelet aggregation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
