2438 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2438)

2438 Results for "decrease" in MCE Product Catalog:

Cat. No.: HY-B0259S3
Indapamide-d6 is a deuterated labeled Indapamide . Indapamide is an orally active sulphonamide diuretic agent, that can reduce blood pressure by decreasing vascular reactivity and peripheral vascular resistance. Indapamide is also can reduce left ventricular hypertrophy .
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Cat. No.: HY-B1132R
CAS No.: 3485-62-9
Synonyms: Ro 2-3773 (Standard)
Research Areas:  

Neurological Disease

Clidinium (bromide) (Standard) is the analytical standard of Clidinium (bromide). This product is intended for research and analytical applications. Clidinium bromide is a quaternary amine antimuscarinic agent. Clidinium bromide may help symptoms of cramping and abdominal/stomach pain by decreasing stomach acid, and slowing the intestines in vivo .
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Cat. No.: HY-N0398R
CAS No.: 80681-44-3
Sec-O-Glucosylhamaudol (Standard) is the analytical standard of Sec-O-Glucosylhamaudol. This product is intended for research and analytical applications. Sec-O-Glucosylhamaudol is a natural compound extracted from Peucedanum japonicum Thunb, decreases levels of μ-opioid receptor, with analgesic effect .
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Cat. No.: HY-P11915
Research Areas:  

Inflammation/Immunology

GG13 is an anti-inflammatory peptide. GG13 reduces the expression of STAT1, NOS2, COX2, and CD40. GG13 decreases the expression and secretion of iNOS and TNF-α proteins. GG13 is applicable to the research of inflammatory diseases .
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Cat. No.: HY-P1841
CAS No.: 89750-15-2
Glucagon-Like Peptide (GLP) II, human is a 33-amino acid peptide derived from the C-terminal of proglucagon and mainly produced by the intestinal L cells. Glucagon-Like Peptide (GLP) II, human stimulates intestinal mucosal growth and decreases apoptosis of enterocytes .
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Cat. No.: HY-W017423R
CAS No.: 6485-40-1
(-)-Carvone (Standard) is the analytical standard of (-)-Carvone. This product is intended for research and analytical applications. (-)-Carvone is an insect neurotoxin and a irreversible acetylcholinesterase (AChE) inhibitor. (-)-Carvone can be used as a bird repellent, inhibits larval growth, decreases pupatation rate, and increases mortality of larvae .
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Cat. No.: HY-W273690
CAS No.: 1028-33-7
Synonyms: 1-Hexyltheobromine; Hexyltheobromine
Pentifylline (1-Hexyltheobromine; Hexyltheobromine), PTX (HY-B0715) precursor compound, is a vasodilator. Pentifylline decreases procollagen levels and inhibits collagen production. Pentifylline reduces functional nuclear NF-1 to suppress procollagen gene transcription .
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Cat. No.: HY-W754654
Epothilone B-d3 (synthetic) is the deuterium labeled Epothilone B (HY-17029). Epothilone B is a microtubule stabilizer with a Ki of 0.71μM. It acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation.
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Cat. No.: HY-101079
CAS No.: 112282-24-3
Purity:  98.14%
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

BRL 52537 hydrochloride is a highly selective κ-Opioid receptor (KOR) agonist with Kis of 0.24 nM and 1560 nM for κ and μ subtypes, respectively. BRL 52537 hydrochloride decreases ischemia-evoked NO production as a potential mechanism of neuroprotection. BRL 52537 hydrochloride attenuates early stroke damage .
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Cat. No.: HY-101220
CAS No.: 24140-98-5
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

RMI-61140 is an orally active neuroleptics. RMI-61140 decreases spontaneous motility and muscle tone in mice. RMI-61140 increases barbit urate-induced sleep and causes eyelid ptosis. RMI-61140 can be used for schizophrenia research .
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Cat. No.: HY-105651A
CAS No.: 56974-46-0
Target:  

Cholinesterase (ChE)

Research Areas:  

Cardiovascular Disease

Butalamine (hydrochloride) is a peripheral vasodilator with local anesthetic effects. :Butalamine (hydrochloride) can produce in animals coronary vasodilation, local anaesthesia, analgesia and a papaverine like action in duodenal preparations. Butalamine (hydrochloride) causes a slowing in rate of spontaneous activity, a decrease in amplitude and a reduction in isolated human smooth muscle .
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Cat. No.: HY-106405
CAS No.: 274925-86-9
Purity:  99.89%
Synonyms: BIA 3-202
Target:  

COMT

Research Areas:  

Metabolic Disease

Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT, and it is potential for the treatment of Parkinson's disease .
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Cat. No.: HY-108300R
CAS No.: 16777-42-7
Oxyfedrine hydrochloride (Standard) is the analytical standard of Oxyfedrine (hydrochloride) (HY-108300). This product is intended for research and analytical applications. Oxyfedrine hydrochloride, a vasodilator, is an orally active β-adrenoreceptor agonist. Oxyfedrine decreases the tonicity of coronary vessels. Oxyfedrine hydrochloride can be used in the research of cardiovascular disease .
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Cat. No.: HY-111142
CAS No.: 91595-86-7
Target:  

Others

Research Areas:  

Others

COR 32-24 is a compound that enters the brain through the purine transport system and has the activity of being transported by this system. The brain uptake index of COR 32-24 in rats decreases with the increase of the concentration of unlabeled compound, and its affinity for purine transporters is higher than that for adenine.
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Cat. No.: HY-113608
CAS No.: 1018830-99-3
Target:  

Adenosine Receptor

Research Areas:  

Neurological Disease

VCP171 is a potent adenosine A1 receptor (A1R) positive allosteric modulator (PAM). VCP171 is effective at decreasing excitatory synaptic currents in Lamina II of neuropathic pain model. VCP171 can be used for researching neuropathic pain .
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Cat. No.: HY-113896
CAS No.: 103494-23-1
Research Areas:  

Others

U-67827E is a cholecystokinin (CCK) agonist that decreases food intake over a prolonged period of time in baboons. U-67827E may affect the latency to food by inhibiting the movement of food in the stomach and magnifying a gastric distention signal .
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Cat. No.: HY-117420
CAS No.: 1350296-29-5
Target:  

Sigma Receptor

Research Areas:  

Cancer

CM764 is an activator for sigma receptor with Ki of 86.6 and 3.5 nM for sigma-1 receptor and sigma-2 receptor. CM764 increases cytoplasmic calcium, NAD +/NADH, and ATP levels, and decreases the concentration of ROS .
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Cat. No.: HY-119994
CAS No.: 301338-95-4
Purity:  99.3%
Research Areas:  

Others

DFPM activates plant resistance protein signaling in roots, and triggers root growth arrest. DFPM decreases root cell viability in accession Col-0. DFPM is light sensitive in aqueous solutions. DFPM becomes bioactive during light and oxygen-dependent modification .
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Cat. No.: HY-122145
CAS No.: 6860-12-4
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Ypenyl hydrochloride is a cytostatic. Ypenyl hydrochloride, belonging to the alkylating agent class, exhibits clear genotoxicity and cell cycle disruption properties. Ypenyl hydrochloride induces chromosomal aberrations in broad bean root tip meristem cells and leads to a decrease in the mitotic index. Ypenyl hydrochloride may be used in cancer research .
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Cat. No.: HY-126749
CAS No.: 2223027-70-9
Target:  

Histamine Receptor

Research Areas:  

Others

VUF14738 (compound 28) is a bidirectional photoswitch antagonist that can rapidly and reversibly photoisomerize at the histamine H3 receptor, with binding affinity increased or decreased upon illumination, and can be used in real-time electrophysiological experiments to study the activity of dynamic light modulation of receptor activation.
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