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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
961 Results for "
Nucleic
" in MedChemExpress (MCE) Product Catalog:
Products (961)
961 Results for "Nucleic" in MCE Product Catalog:
2
2 Cited Publications
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2
2 Cited Publications
Cat. No.: HY-W009163
CAS No.: 957-75-5
Research Areas:
5-Bromouridine is a brominated uridine nucleoside. The triphosphate form of 5-Bromouridine, 5BrdUTP, can substitute for TTP as a substrate for DNA polymerase and be incorporated into nascent DNA strands, rendering the resulting 5-bromouridine-labeled DNA photosensitive to 300 nm UV irradiation; upon UV irradiation, the 5BrdU signal decreases and dU is generated, accompanied by DNA strand breaks and cross-link formation. 5-Bromouridine is useful for studies on nucleoside structure and halogenated nucleoside-labeled nucleic acids .
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2 Cited Publications
Target:
Research Areas:
N3-TEMPO is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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2 Cited Publications
Cat. No.: HY-153713
Purity: 98.05%
MYC-RIBOTAC is a nucleic acid-targeting degrader (ribonuclease-targeting chimera, RIBOTAC) that targets the MYC internal ribosome entry site (IRES). MYC-RIBOTAC contains a MYC mRNA binding component and a small molecule that recruits and locally activates RNAse L1. MYC-RIBOTAC reduces MYC mRNA and protein expression levels, induces cell apoptosis, and can be used for antitumor research . MYC-RIBOTAC consists of pre-miR-155 binder Anticancer agent 167 (HY-156839), RNA binder NCI-B16 (HY-156215), and Linker Amino-PEG4-alcohol (HY-W008005).
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2 Cited Publications
Cat. No.: HY-D0150
CAS No.: 107091-89-4
1
1 Cited Publications
Cat. No.: HY-D1723
EthD-III is a nucleic acid probe. EthD-III is a red fluorescent stain that can be used to detect dead cells. EthD-III enters cells with damaged membranes and binds to nucleic acids, resulting in bright red fluorescence in dead cells (Ex/Em=530/645 nm) .
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1 Cited Publications
Cat. No.: HY-137265
CAS No.: 62442-61-9
Target:
Research Areas:
Aminomethyltrioxsalen hydrochloride is a psoralen derivative. Aminomethyltrioxsalen hydrochloride can penetrate intact cells and react with nucleic acid secondary structures in vivo without disrupting the tissue structure of natural nucleoproteins. Aminomethyltrioxsalen hydrochloride inactivates viruses by crosslinking nucleic acid pyrimidine residues after exposure to UV-A radiation. Aminomethyltrioxsalen hydrochloride can be used in research related to dengue virus infection .
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1 Cited Publications
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Research Areas:
4'-Aminomethyl-4,5',8-trimethylpsoralen is a photoreactive agent for crosslinking nucleic acids .
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1
1 Cited Publications
1
1 Cited Publications
Cat. No.: HY-I0960S4
CAS No.: 24897-52-7
1
1 Cited Publications
Cat. No.: HY-P2963
CAS No.: 54576-84-0
Target:
Research Areas:
Nuclease P1 is a single-stranded specific endonuclease, it hydrolyzes nucleic acids into 5'-mononucleotides and cleaves the single-stranded region of a double-stranded nucleic acid. Nuclease P1 is one of the most well-known single stranded specific nucleases in the field of molecular biology, it is widely used in the pharmaceutical and food industries . Nuclease P1 can be obtained by fermentation of Penicillium citrinum: through extraction process, ultrafiltration concentration, drying and purification, etc.
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1 Cited Publications
Cat. No.: HY-D0941
CAS No.: 150322-05-7
1
Solvent and Concentration: Sterile water: 10 mg/Ml
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1 Cited Publications
Cat. No.: HY-19743
CAS No.: 928659-17-0
Research Areas:
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent. Triazavirin works by inhibiting the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is also an effective protective agent on the transmission stage of influenza .
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1 Cited Publications
Cat. No.: HY-P71625
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PARK7; Parkinsonism-Associated Deglycase; Parkinsonism Associated Deglycase; Parkinson Disease Protein 7; DJ-1; Parkinson Protein 7; Protein/Nucleic Acid Deglycase DJ-1; Oncogene DJ1; Maillard Deglycase; Epididymis Secretory Sperm Binding Protein Li 67p;
Species:
Human
Source:
E. coli
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1 Cited Publications
Cat. No.: HY-P74653
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PARK7; Parkinsonism-Associated Deglycase; Parkinsonism Associated Deglycase; Parkinson Disease Protein 7; DJ-1; Parkinson Protein 7; Protein/Nucleic Acid Deglycase DJ-1; Oncogene DJ1; Maillard Deglycase; Epididymis Secretory Sperm Binding Protein Li 67p;
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-W008990
CAS No.: 25899-70-1
Synonyms: 5'-Xanthylic acid sodium salt
Target:
Research Areas:
Xanthosine 5'-monophosphate sodium salt (5'-Xanthylic acid sodium salt) is an intermediate in purine metabolism. Xanthosine 5'-monophosphate sodium salt can be used for genetic code, nucleic acid structure, and DNA, RNA and protein synthesis research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
