Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
128 Results for "
hypotensive
" in MedChemExpress (MCE) Product Catalog:
Products (128)
128 Results for "hypotensive" in MCE Product Catalog:
Cat. No.: HY-132277S
Purity: 96.65%
Cat. No.: HY-112074A
CAS No.: 51274-83-0
Synonyms: HOE 440 hydrochloride
Target:
Research Areas:
Tiamenidine hydrochloride (HOE 440 hydrochloride) is a centrally acting α1-adrenergic receptor antagonist with hypotensive activity. Tiamenidine hydrochloride regulates blood pressure levels by binding to α1 receptors. Tiamenidine hydrochloride can be used in the study of hypertension .
Cat. No.: HY-21065R
CAS No.: 40180-04-9
Synonyms: Ticrynafen (Standard); ANP 3624 (Standard)
Target:
Research Areas:
Tienilic acid (Standard) is the analytical standard of Tienilic acid. This product is intended for research and analytical applications. Tienilic acid (Ticrynafen; ANP 3624) acts as a diuretic hypotensive agent. However, Tienilic acid induces hepatotoxicity. Tienilic acid is converted into electrophilic metabolites by cytochrome P450 (CYP) in vitro .
Cat. No.: HY-N4209
CAS No.: 54483-84-0
Category:
Uncaria tomentosa (Willd. ex Schult.) DC. Alkaloids Other Alkaloids Plants Rubiaceae Extract
Target:
Cat. No.: HY-114385
CAS No.: 2557327-99-6
Synonyms: 13,14-epoxy Fluprostenol isopropyl ester
Target:
Research Areas:
13,14-epoxy Travoprost (13,14-epoxy Fluprostenol isopropyl ester) is a mixture of diastereomeric epoxides generated during production of Travoprost (HY-B0584). Travoprost is a selective agonist for prostaglandin F receptor, which exhibits an ocular hypotensive efficacy .
Cat. No.: HY-121653B
CAS No.: 98205-89-1
Synonyms: DU-29373
Target:
Research Areas:
Flesinoxan hydrochloride is a hypotensive agent and a potent, high affinity and selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist with an EC50 value of 24 nM. Flesinoxan hydrochloride also has effective anxiolytic/antidepressant effects .
Cat. No.: HY-120405
CAS No.: 137550-79-9
Target:
Research Areas:
RS-12254 is a compound with hypotensive, diuretic and sympathostatic effects, and has the activity of regulating blood pressure, water and salt metabolism and sympathetic nerve activity. RS-12254 can lower blood pressure, reduce plasma norepinephrine levels, has diuretic and natriuretic effects, and has sympathostatic properties.
Cat. No.: HY-146650
CAS No.: 2756125-46-7
Target:
Research Areas:
LpxC-IN-9 (compound 19) is a potent LpxC inhibitor. LpxC-IN-9 has antibacterial and hypotensive effects . LpxC-IN-9 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-B0584S2
Synonyms: Fluprostenol isopropyl ester-7; AL6221-7; Flu-Ipr-7
Cat. No.: HY-B0584A
CAS No.: 1563176-59-9
Synonyms: 5,6-trans-Fluprostenol isopropyl ester; 5,6-trans-AL6221; 5,6-trans-Flu-Ipr
Target:
Research Areas:
5,6-trans-Travoprost is the isomer of Travoprost (HY-B0584), and can be used as an experimental control. Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension .
Cat. No.: HY-129934
CAS No.: 607351-44-0
Synonyms: Lat-NEt
Target:
Research Areas:
Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity.1 Prostaglandin N-ethyl amides were recently introduced as alternative prostaglandin ocular hypotensive prodrugs. Although it has been claimed that prostaglandin ethyl amides are not converted to the free acids in vivo, studies in our laboratories have shown that bovine and human corneal tissue converts the N-ethyl amides of various prostaglandins to the free acids with a conversion rate of about 2.5 μg/g corneal tissue/hr. Lat-NEt would be expected to show the typical intraocular effects of Latanoprost free acid, but with the much slower hydrolysis pharmacokinetics of the prostaglandin N-amides.
Synonyms: Lysine vasopressin (Standard); [Lys8]-Vasopressin (Standard)
Category:
Cat. No.: HY-W753672
CAS No.: 1195030-24-0
Cat. No.: HY-121653R
CAS No.: 98206-10-1
Target:
Research Areas:
Flesinoxan (Standard) is the analytical standard of Flesinoxan. This product is intended for research and analytical applications. Flesinoxan is a hypotensive agent and a potent, high affinity and selective 5-hydroxytryptamine1A (5-HT1A) receptor agonist with an EC50 value of 24 nM. Flesinoxan also has effective anxiolytic/antidepressant effects .
Cat. No.: HY-163994
CAS No.: 57576-17-7
Synonyms: KWD 2058 hydrochloride
Target:
Research Areas:
Ibuterol (KWD 2058) hydrochloride, a diester of Terbutaline (HY-B0802A), is an orally active, selective and effective β-stimulating agent with lipophilic activities. Ibuterol hydrochloride is also an orally active ocular hypotensive agent. Ibuterol hydrochloride relieves bronchial obstruction in asthma without causing circulatory effects. Ibuterol hydrochloride is proming for rasearch of intraocular hypertension, asthma and bronchitis .
Cat. No.: HY-117763
CAS No.: 144092-66-0
Target:
Research Areas:
A-39355 is a compound that can overcome multidrug resistance and has the activity of reversing multidrug resistance. A-39355 can enhance the cytotoxicity of antitumor compounds in multidrug-resistant cells, increase the accumulation of compounds in cells, inhibit the efflux of compounds, and compared with calcium antagonists, it has no serious hypotensive effect. Its activity may be unrelated to the ability to block calcium transport.
Cat. No.: HY-W751400
CAS No.: 6106-33-8
Synonyms: Purapuridine hydrochloride; Solancarpidine hydrochloride; Solasodin hydrochloride
Target:
Research Areas:
Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Solasodine (Purapuridine) hydrochloride is a steroidal alkaloid that occurs in plants of the Solanaceae family. Solasodine hydrochloride induces apoptosis by inhibiting the p53-MDM2 complex, p21Waf1/Cip1, and Bcl-2 proteins. Solasodine hydrochloride has neuroprotective, antifungal, hypotensive, anticancer, antiatherosclerotic, antiandrogenic and anti-inflammatory activities .
Cat. No.: HY-129934S
Synonyms: Lat-NEt-d4
Cat. No.: HY-14561AR
CAS No.: 79944-56-2
Synonyms: RX 781094 hydrochloride (Standard)
Research Areas:
Idazoxan (hydrochloride) (Standard) is the analytical standard of Idazoxan (hydrochloride). This product is intended for research and analytical applications. Idazoxan hydrochloride (RX 781094 hydrochloride) is an α2-adrenoceptor antagonist and is also a imidazoline receptors (IRs) antagonist competitively antagonized the centrally induced hypotensive effect of imidazoline-like agents (IMs). Idazoxan hydrochloride also improves motor symptoms in Parkinson’s disease, L-DOPA-induced dyskinesias, and experimental Parkinsonism .
Cat. No.: HY-B0098B
CAS No.: 70918-17-1
Synonyms: (R)-UK 33274
Target:
Research Areas:
(R)-Doxazosin ((R)-UK 33274) is an isomer of Doxazosin, a selective and orally active a1-adrenoceptor agonist. Doxazosin can be used for systemic antihypertensive and ocular hypotensive. Doxazosin exerts its antihypertensive effect by reducing total peripheral resistance by selective postsynaptic a1-blockade, without reducing cardiac output. Doxazosin can significantly lower both standing and supine blood pressure .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
