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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
97 Results for "
Probe substrate
" in MedChemExpress (MCE) Product Catalog:
Products (97)
97 Results for "Probe substrate" in MCE Product Catalog:
Cat. No.: HY-134392A
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6-Alkyne-NAD+ sodium is a nicotinamide adenine dinucleotide (NAD) analogue. 6-Alkyne-NAD+ sodium can be used as a fluorescent probe coupled with fluorescent labels for marking ADP-ribose polymerase substrate proteins .
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5-Amino-2'-deoxyuridine is a thymidine analogue and substrate for chemical reaction. 5-Amino-2'-deoxyuridine can be use in the preparation of labeled probes for DNA microarray analysis .
Cat. No.: HY-108286B
CAS No.: 71369-60-3
Synonyms: (+)-Cordanum
Research Areas:
(+)-Talinolol is an isomer of Talinolol (HY-108286). Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol exhibits cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used probe substrate for P-glycoprotein (P-gp) activity .
Cat. No.: HY-108286A
CAS No.: 71369-59-0
Synonyms: (-)-Cordanum
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(-)-Talinolol ((-)-Cordanum) is the S-configuration levorotatory single optical enantiomer of the racemic mixture of Talinolol (HY-108286). Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol possesses cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used substrate for P-glycoprotein (P-gp) active probes.
Cat. No.: HY-108286R
CAS No.: 57460-41-0
Synonyms: Cordanum (Standard)
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Talinolol (Standard) is the analytical standard of Talinolol (HY-108286). This product is intended for research and analytical applications. Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol exhibits cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used probe substrate for P-glycoprotein (P-gp) activity .
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Guanosine 5′-(tetrahydrogen triphosphate), 1-methyl-
Cat. No.: HY-177582
CAS No.: 52940-67-7
Cat. No.: HY-203233
CAS No.: 126111-99-7
Cat. No.: HY-D3166
CAS No.: 2413816-64-3
Cat. No.: HY-156230
CAS No.: 2855124-74-0
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Man-GIcNAc-oxazoline is a disaccharide oxazoline based on Manβ1,4GlcNAc. Man-GIcNAc-oxazoline serves as a donor substrate for transglycosylation in endoglycosidase-mediated antibody Fc glycan remodeling. Man-GIcNAc-oxazoline can be modified with azides, PEG-linked azides, fluorescent probes, biotin groups, ligands or prodrugs. Man-GIcNAc-oxazoline can be used for the synthesis of antibody-drug conjugates (ADC). Man-GIcNAc-oxazoline is applicable for cancer research .
Cat. No.: HY-CE00983A
Synonyms: 4-Pentynoyl-CoA TFA
Cat. No.: HY-100201R
CAS No.: 1982372-88-2
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A-196 (Standard) is the analytical standard of A-196 (HY-100201). This product is intended for research and analytical applications. A-196 is a potent and selective inhibitor of SUV420H1 and SUV420H2 with IC50 values of 25 nM and 144 nM, respectively. A-196 inhibits SUV4-20 biochemically in a substrate-competitive manner. A-196 represents a first-in-class chemical probe of SUV4-20 to investigate the role of histone methyltransferases in genomic integrity .
Cat. No.: HY-W750220
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4-Methylumbelliferyl β-D-glucuronide dihydrate is a fluorescent substrate and fluorescent probe used to detect the activity of β-D-glucuronidase. 4-Methylumbelliferyl β-D-glucuronide dihydrate also serves as a surrogate for assessing fecal coliform contamination in aquatic environments. 4-Methylumbelliferyl β-D-glucuronide dihydrate releases 4-methylumbelliferone via enzyme-mediated cleavage of the β-glycosidic bond; the latter emits fluorescence under alkaline conditions, with an excitation wavelength of 365-366 nm and an emission wavelength of 444 nm .
Synonyms: Acexamic acid (Standard); 6-Acetamidocaproic acid (Standard)
Cat. No.: HY-110210R
CAS No.: 146616-66-2
Synonyms: BODIPY FL,SE (Standard)
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BODIPY-FL NHS ester (Standard) is the analytical standard of BODIPY-FL NHS ester (HY-110210). This product is intended for research and analytical applications. BODIPY FL NHS ester (BODIPY FL, SE) is a cell membranes-penatrable amine-reactive fluorescent probe. The maximum excitation/emission wavelength of the BODIPY-FL NHS ester are 502/511 nm, respectively. BODIPY-FL NHS ester has high stability and is insensitive to the polarity, pH and type of solvent, and can maintain stable fluorescence properties under different environmental conditions. BODIPY-FL NHS ester can be used for the synthesis of protease substrates, live cell imaging, protein labeling and immunoassay .
Cat. No.: HY-D3436
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Pt-Luc is a bioluminescent probe used for real-time, non-invasive monitoring of Pt (IV) prodrug reduction in living cells and animal models. The detection mechanism of Pt-Luc relies on the intracellular reduction mediated by active cysteine residues in proteins. Pt-Luc can penetrate the membrane of living cells; after entering cells, active cysteine thiolates in high-molecular-weight protein components reduce the Pt (IV) complex, thereby cleaving the caged aminoluciferin substrate. The released free aminoluciferin is then oxidized by luciferase in the presence of ATP to generate a bioluminescent signal, whose intensity is directly correlated with the reduction degree of Pt (IV) .
Cat. No.: HY-D3187
CAS No.: 2484831-02-7
Cat. No.: HY-D3186
CAS No.: 2163840-29-5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
