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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1103 Results for "
Biosynthesis
" in MedChemExpress (MCE) Product Catalog:
Products (1103)
1103 Results for "Biosynthesis" in MCE Product Catalog:
Cat. No.: HY-N0667S3
CAS No.: 286460-82-0
Synonyms: (-)-Asparagine-13C4 monohydrate; Asn-13C4 monohydrate; Asparamide-13C4 monohydrate
Cat. No.: HY-N0667S4
CAS No.: 286437-12-5
Synonyms: (-)-Asparagine-4-13C monohydrate; Asn-4-13C monohydrate; Asparamide-4-13C monohydrate
Cat. No.: HY-N2183R
CAS No.: 18609-17-1
Synonyms: Quercetin 3-O-sophoroside (Standard)
Category:
Flavonols Flavonoids Phenols Polyphenols Plants Apocynum venetum Linn. Apocynaceae Extract
Target:
Cat. No.: HY-N21878
CAS No.: 474328-38-6
Category:
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Cat. No.: HY-N7101R
CAS No.: 87239-81-4
Synonyms: U-76,252 (Standard); CS-807 (Standard)
Research Areas:
Cefpodoxime Proxetil (Standard) is the analytical standard of Cefpodoxime Proxetil. This product is intended for research and analytical applications. Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases .
Cat. No.: HY-N9484S
CAS No.: 3028870-62-1
Cat. No.: HY-P10192
CAS No.: 717122-86-6
Synonyms: ABri peptide (1-23); ABri23
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Cat. No.: HY-W017443R
CAS No.: 5794-13-8
Category:
Cat. No.: HY-W017443S1
CAS No.: 204451-47-8
Cat. No.: HY-W654334
Cat. No.: HY-W778179
CAS No.: 1329840-53-0
Synonyms: LRCL 3794-13C,d3
Cat. No.: HY-Y1139S2
CAS No.: 78629-92-2
Synonyms: Heptanedioic acid-13C2; 1,5-Pentanedicarboxylic acid-13C2; 1,7-Heptanedioic acid--13C2
Research Areas:
Pimelic acid- 13C2 (Heptanedioic acid- 13C2) is the 13C-labeled Pimelic acid (HY-Y1139). Pimelic acid (Heptanedioic acid; 1,5-Pentanedicarboxylic acid) is a seven-carbon α,ω-dicarboxylic acid and a downstream product of fatty acid synthesis. Pimelic acid is a key precursor in biotin biosynthesis. Pimelic acid can be converted to pimelic acid-CoA by the BioW enzyme, thereby bypassing exogenous biotin requirements to support growth in various biotinytrophic bacteria and fungi, and reversing antibiotic-induced inhibition of biotin synthesis. Furthermore, Pimelic acid has been proposed as a highly specific biomarker for oxygen-induced retinopathy in mice. Pimelic acid can be used to study retinopathy of preterm infants, oxygen-induced retinopathy, and microbial biotin metabolism .
Cat. No.: HY-L146
4,407 compounds
Metabolism is the set of life-sustaining chemical reactions in organisms that maintain cell homeostasis. Metabolic pathways are enzyme-mediated biochemical reactions that lead to biosynthesis (anabolism) or breakdown (catabolism) of molecules including glucose metabolism, lipid metabolism and amino acid or protein metabolism within a cell or tissue. As catalysts, enzymes are crucial to metabolism as they allow a reaction to proceed more rapidly and tregulate the rate of a metabolic reaction. Due to the importance of metabolic balance in the organism, the abnormal function of metabolic enzymes often leads to the occurrence of a variety of metabolic diseases, such as diabetes, obesity, cardiovascular disease, etc.
MCE designs a unique collection of 4,407 metabolic enzymes related small molecules, which is an important tool for studying the metabolic activities of organisms and developing drugs for metabolic diseases.
Synonyms: SAN 9789
Research Areas:
Norflurazon (SAN 9789) is a pre-emergence Herbicide. Norflurazon non-competitively inhibits phytoene desaturase by competing with the enzyme cofactor and disrupts carotenoid biosynthesis, thereby leading to chlorophyll photodegradation and chlorosis. Norflurazon inhibits MGDG synthase, CDP-choline phosphotransferase, Omega-3 FAD7 desaturase, and PG delta-3-trans desaturase, and activates LysoPC-acyltransferase and Omega-3 FAD3 desaturase. Norflurazon inhibits photosynthetic membrane organization, mitochondrial respiration, ATP production, PI3K signaling, and ERK1/2 phosphorylation. Norflurazon activates MAPK P38 phosphorylation and ER stress signaling. Norflurazon induces morphological malformations and cardiovascular effects in zebrafish embryos .
Cat. No.: HY-118386
CAS No.: 1060478-12-7
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Research Areas:
H2-005 is a compound that selectively inhibits diacylglycerol acyltransferase 2 (DGAT2) and has the activity to inhibit triacylglycerol synthesis in hepatocytes and preadipocytes. H2-005 significantly reduces triacylglycerol biosynthesis in HepG2 hepatocytes and 3T3-L1 preadipocytes. H2-005 exhibits specific inhibitory activity in DGAT2-overexpressing HEK293 cells. H2-005 almost completely inhibits lipid droplet formation in 3T3-L1 cells when co-treated with a DGAT1 inhibitor. H2-005 will contribute to DGAT2-related lipid metabolism research and the development of drugs to inhibit metabolic diseases .
Cat. No.: HY-12502B
CAS No.: 111011-53-1
Synonyms: NZ-105 hydrochloride; (±)-Efonidipine hydrochloride
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Efonidipine (NZ-105) hydrochloride is an orally active dual L-type and T-type calcium channel blocker (CCB) with IC50 values of 1.8 and 350 nM, respectively. Efonidipine hydrochloride inhibits SARS-CoV-2 main protease. Efonidipine hydrochloride modulates adrenal steroidogenesis by increasing the expression of steroidogenic acute regulatory protein (StAR), dbcAMP-or angiotensin II-induced StAR mRNA expression and DHEA-S production, while suppressing the biosynthesis of aldosterone and cortisol. Efonidipine hydrochloride reduces plasma aldosterone levels in vivo. Efonidipine hydrochloride improves cardiac function in heart failure models by inhibiting T-type calcium channels (via both tonic and use-dependent blockade), independently of blood pressure reduction. Efonidipine hydrochloride can be used for research in hypertension, heart failure, and disorders involving dysregulated steroid hormone synthesis .
Cat. No.: HY-125818S5
Synonyms: Cytidine triphosphate-15N3,d14 dilithium; 5'-CTP-15N3,d14 dilithium
Cat. No.: HY-13948BS
Purity: 98.11%
Synonyms: Angiotensin II-13C6,15N TFA; Ang II-13C6,15N TFA; DRVY(I-13C6,15N)HPF TFA
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Research Areas:
Cat. No.: HY-189221
Antimicrobial agent-56 is an antimicrobial agent that targets the cell membrane of drug-resistant bacteria. Antimicrobial agent-56 disrupts the cell membrane integrity of methicillin-resistant Staphylococcus aureus (MRSA) via membrane targeting, downregulates lipoteichoic acid biosynthesis and two-component system signaling, inhibits MRSA biofilm formation and eradicates mature biofilms, with a MIC of 6.25 μg/mL. Antimicrobial agent-56 hardly induces drug resistance, exhibits low hemolytic activity, inhibits NO production stimulated by LPS (HY-D1056), and retains the anti-inflammatory activity of Resveratrol (HY-16561). Antimicrobial agent-56 loaded in PVA-SA hydrogel promotes the healing of MRSA-infected wounds and suppresses inflammation. Antimicrobial agent-56 can be used in studies related to MRSA infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
