Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1329 Results for "
synthases
" in MedChemExpress (MCE) Product Catalog:
Products (1329)
1329 Results for "synthases" in MCE Product Catalog:
Cat. No.: HY-B2004R
CAS No.: 130000-40-7
Research Areas:
Thifluzamide (Standard) is the analytical standard of Thifluzamide. This product is intended for research and analytical applications. Thifluzamide is a fungicide that inhibits fungal respiration by blocking the ubiquinone-binding site in mitochondrial complex II. Thifluzamide exhibits significant activity against Basidiomycota pathogens (such as Rhizoctonia cerealis, Ustilago and Puccinia genera) and is commonly used in studies on wheat sharp eyespot. Thifluzamide displays a dual mechanism in regulating lipid metabolism: it reduces fatty acid synthase activity to inhibit endogenous fatty acid synthesis, and increases carnitine palmitoyltransferase-I activity to accelerate fatty acid β-oxidation, thereby reducing total cholesterol and triglyceride levels in the liver. Thifluzamide also induces hepatotoxicity in zebrafish models and carries a risk of developmental toxicity. Thifluzamide inhibition of Rhizoctonia cerealis may result in low to moderate levels of drug resistance, leading to the generation of stable drug-resistant mutants .
Cat. No.: HY-W010918R
CAS No.: 58-64-0
Synonyms: Adenosine diphosphate (Standard); ADP (Standard)
Cat. No.: HY-126473
CAS No.: 70010-76-3
Research Areas:
NE97220 is a biochemical reagent. NE97220 induces macrophage apoptosis and reduces their viability, leading to internucleosomal DNA fragmentation. NE97220 inhibits the growth of Trypanosoma brucei rhodesiense . NE97220 is used in research on human African trypanosomiasis and immune-related studies .
Synonyms: Malvidin-3-O-glucoside chloride; Oenin chloride
Cat. No.: HY-141466A
Purity: 97.85%
Research Areas:
Crotonyl-CoA tetrasodium, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA tetrasodium is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA tetrasodium acts as a substrate for p300’s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA tetrasodium regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA tetrasodium serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA tetrasodium can be used for the research of LPS-induced inflammatory response .
Cat. No.: HY-166309
CAS No.: 116912-55-1
Research Areas:
Crotonyl-CoA tetralithium, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA tetralithium is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA tetralithium acts as a substrate for p300’s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA tetralithium regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA tetralithium serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA tetralithium can be used for the research of LPS-induced inflammatory response .
Synonyms: Succinyl-coenzyme A; S-(Hydrogen succinyl)coenzyme A
Target:
Cat. No.: HY-CE01038
CAS No.: 74875-70-0
Synonyms: 3-Hydroxyhexanoyl-coenzyme A; [R,S]-Lactyl-CoA
Target:
Research Areas:
3-Hydroxyhexanoyl-CoA (3-Hydroxyhexanoyl-coenzyme A) is a derivative of coenzyme A, which is produced from hexanoic acid via β-oxidation .
Cat. No.: HY-N17632
CAS No.: 73338-86-0
Category:
Target:
Cat. No.: HY-W004812
CAS No.: 161660-94-2
Synonyms: (1S,3S)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid
Target:
Research Areas:
BOC-(1R,3S)-3-aminocyclopentane carboxylic acid ((1S,3S)-3-[(tert-Butoxycarbonyl)amino]cyclopentanecarboxylic acid) is a conformationally constrained peptide building block and a key component of SARS-CoV-2 main protease (Mpro) inhibitors. When incorporated into macrocyclic peptides, BOC-(1R,3S)-3-aminocyclopentane carboxylic acid not only helps generate high-affinity Mpro inhibitors by preorganizing the secondary structure of peptides, but also exerts sequence-dependent functional inhibition on the hydrolytic activity of Mpro. BOC-(1R,3S)-3-aminocyclopentane carboxylic is widely used in COVID-19-related research .
Cat. No.: HY-W008385
CAS No.: 156-86-5
Synonyms: L-Homoarginine
Cat. No.: HY-W008385AS
Synonyms: L-Homoarginine-d4 dihydrochloride
H-HoArg-OH-d4 dihydrochloride (L-Homoarginine-d4 dihydrochloride) is the d4-labeled H-HoArg-OH dihydrochloride. H-HoArg-OH dihydrochloride (L-Homoarginine dihydrochloride) is an orally active endogenous non-protein amino acid. H-HoArg-OH dihydrochloride acts as a weak alternative substrate for NOS and interferes with NO production, selectively inhibits tissue-nonspecific alkaline phosphatase (TNAP), and suppresses the uptake of arginine by y +-type transporters (system y +). H-HoArg-OH dihydrochloride increases tissue hArg concentrations in vivo, regulates amino acid homeostasis, and improves renal function and pathological features of diabetic nephropathy. H-HoArg-OH dihydrochloride can be used in studies related to diabetes and cardiomyopathy .
Cat. No.: HY-W008385R
CAS No.: 156-86-5
Synonyms: L-Homoarginine (Standard)
Cat. No.: HY-W008385S
CAS No.: 1332075-41-8
Synonyms: L-Homoarginine-d4
Research Areas:
H-HoArg-OH-d4 (L-Homoarginine-d4) is the d4-labeled H-HoArg-OH (HY-W008385). H-HoArg-OH (L-Homoarginine) is an orally active endogenous non-protein amino acid. H-HoArg-OH acts as a weak alternative substrate for NOS and interferes with NO production, selectively inhibits tissue-nonspecific alkaline phosphatase (TNAP), and suppresses the uptake of arginine by y +-type transporters (system y +). H-HoArg-OH increases tissue hArg concentrations in vivo, regulates amino acid homeostasis, and improves renal function and pathological features of diabetic nephropathy. H-HoArg-OH can be used in studies related to diabetes and cardiomyopathy .
Cat. No.: HY-W008829
CAS No.: 685-91-6
Research Areas:
N,N-Diethylacetamide is a polar solvent widely used in film and fiber manufacturing, as well as in laboratories as a carrier for water-insoluble chemicals. N,N-Diethylacetamide exerts potent anti-inflammatory effects by inhibiting the NF-κB pathway, suppressing the expression of NO and iNOS, and downregulating key inflammatory cytokines such as TNF-α and IL-6, without affecting the MAPK pathway. N,N-Diethylacetamide can be used to study inflammatory preterm birth.
Cat. No.: HY-W012340
CAS No.: 1483-01-8
Synonyms: L-Homoarginine hydrochloride
Cat. No.: HY-W012340R
CAS No.: 1483-01-8
Cat. No.: HY-W012340S
CAS No.: 2483830-23-3
Synonyms: L-Homoarginine-13C7,15N4 hydrochloride
H-HomoArg-OH- 13C7, 15N4 hydrochloride (L-Homoarginine- 13C7, 15N4 hydrochloride) is the 15N, 13C-labeled H-HomoArg-OH (hydrochloride) (HY-W012340). H-HomoArg-OH hydrochloride (L-Homoarginine hydrochloride) is an orally active endogenous non-protein amino acid. H-HomoArg-OH hydrochloride acts as a weak alternative substrate for NOS and interferes with NO production, selectively inhibits tissue-nonspecific alkaline phosphatase (TNAP), and suppresses the uptake of arginine by y +-type transporters (system y +). H-HomoArg-OH hydrochloride increases tissue hArg concentrations in vivo, regulates amino acid homeostasis, and improves renal function and pathological features of diabetic nephropathy. H-HomoArg-OH hydrochloride can be used in studies related to diabetes and cardiomyopathy .
Target:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
