181 Results for "

embryo

" in MedChemExpress (MCE) Product Catalog:
Products (181)

181 Results for "embryo" in MCE Product Catalog:

Cat. No.: HY-W654342
Synonyms: NSC 268508-d20; Neuridine-d20
Spermine-d20 (NSC 268508-d20) is deuterium labeled Spermine. Spermine is a natural antioxidant and anti-inflammatory agent. Spermine is known to inhibit some bacterial cultures, especially strains of Staphylococcus aureus. Spermine can reversibly inhibits DNA synthetic response, mixed lymphocyte response and the induction of cytolytic lymphocyte response in primary cultures of murine spleen cells. Spermine is a polyamine nitric oxide donor that can provide nitric oxide to platelets and inhibit platelet activation to a certain extent concentration-dependently. Spermine occurs in mammalian tissues, plants, bacteria, ribosomes and bacteriophage. Spermine tetrahydrochloride inhibits primary human embryo lung fibroblasts in vitro.
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Cat. No.: HY-Y0332K
CAS No.: 7778-77-0
Synonyms: Potassium phosphate monobasic, for cell culture
Potassium dihydrogen phosphate, for cell culture (Potassium phosphate monobasic, for cell culture) is a cell culture reagent. Potassium dihydrogen phosphate, for cell culture activates NF-κB. Potassium dihydrogen phosphate, for cell culture upregulates the expression of dental/osteogenic markers (OCN, DSP/DSPP, OSX, RUNX2, ALP) and enhances the mineralization capacity of human periodontal ligament stem cells. Potassium dihydrogen phosphate, for cell culture promotes the proliferation of human periodontal ligament stem cells in logarithmic growth phase. Potassium dihydrogen phosphate, for cell culture promotes the growth of somatic embryos of Dendrobium Sonia, increases leaf number, leaf length and fresh weight of tissue-cultured seedlings. Potassium dihydrogen phosphate, for cell culture is applicable to periodontal disease-related research .
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Cat. No.: HY-117733
CAS No.: 176050-48-9
Zerumin A is an anti-angiogenic agent that acts on multiple molecular targets related to angiogenesis (including kdr/VEGFR2, angpt1, angpt2, tie1, and tie2). Zerumin A specifically inhibits the proliferation and migration of human umbilical vein endothelial cells (HUVECs) by regulating the VEGF-VEGFR and ANGPT-TIE signaling pathways, and dose-dependently inhibits angiogenesis (10-20 μM significantly inhibits zebrafish embryo angiogenesis). Zerumin A can be used in the research of cancer and angiogenesis-related inflammatory diseases. Zerumin A can be naturally extracted from the 95% ethanol extract of the fruits, seeds, and pericarp of Alpinia caerulea (R.Br.) Bentham (a plant of the Alpinia genus in the Zingiberaceae family) .
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Cat. No.: HY-150119
CAS No.: 1312013-29-8
Target:  

Sirtuin

Research Areas:  

Endocrinology

2'/3'-O-Acetyl-ADP-ribose sodium is an inhibitor of cell division and oocyte maturation. 2'/3'-O-Acetyl-ADP-ribose sodium causes delay or arrest of oocyte maturation and blastomere division in embryos. 2'/3'-O-Acetyl-ADP-ribose sodium is produced by Sir2 family deacetylases during the coupling of histone/protein deacetylation with β-NAD+ cleavage. In neutral or weakly alkaline aqueous solutions, the direct enzymatic product forms of 2'/3'-O-Acetyl-ADP-ribose sodium, namely the 2'-O-acetyl form and the 3'-O-acetyl form, undergo intramolecular lactone exchange reaction and interconvert with each other .
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Cat. No.: HY-Y0332B
CAS No.: 7778-77-0
Potassium dihydrogen phosphate, AR,99.5% is a potassium salt. Potassium dihydrogen phosphate, AR,99.5% activates NF-κB. Potassium dihydrogen phosphate, AR,99.5% upregulates the expression of dental/osteogenic markers (OCN, DSP/DSPP, OSX, RUNX2, ALP) and enhances the mineralization capacity of human periodontal ligament stem cells. Potassium dihydrogen phosphate, AR,99.5% promotes the proliferation of human periodontal ligament stem cells in logarithmic growth phase. Potassium dihydrogen phosphate, AR,99.5% promotes the growth of somatic embryos of Dendrobium Sonia, increases leaf number, leaf length and fresh weight of tissue-cultured seedlings. Potassium dihydrogen phosphate, AR,99.5% is applicable to periodontal disease-related research .
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Cat. No.: HY-P75749
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EPHB3; embryonic Kinase 2; Prev. ETK2; Human embryo Kinase 2; Tyro6; EPH-Like Kinase 2; Hek2; EphB3; Tyrosine-Protein Kinase TYRO6; TYRO6; EPH-Like Tyrosine Kinase 2; HEK2; Ephrin Type-B Receptor 3; EPH Receptor B3; EK2
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P75750
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EPHB3; embryonic Kinase 2; Prev. ETK2; Human embryo Kinase 2; Tyro6; EPH-Like Kinase 2; Hek2; EphB3; Tyrosine-Protein Kinase TYRO6; TYRO6; EPH-Like Tyrosine Kinase 2; HEK2; Ephrin Type-B Receptor 3; EPH Receptor B3; EK2
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P77931
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: EPHB3; embryonic Kinase 2; Prev. ETK2; Human embryo Kinase 2; Tyro6; EPH-Like Kinase 2; Hek2; EphB3; Tyrosine-Protein Kinase TYRO6; TYRO6; EPH-Like Tyrosine Kinase 2; HEK2; Ephrin Type-B Receptor 3; EPH Receptor B3; EK2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78294
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: EPHB3; embryonic Kinase 2; Prev. ETK2; Human embryo Kinase 2; Tyro6; EPH-Like Kinase 2; Hek2; EphB3; Tyrosine-Protein Kinase TYRO6; TYRO6; EPH-Like Tyrosine Kinase 2; HEK2; Ephrin Type-B Receptor 3; EPH Receptor B3; EK2
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P702711
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: EPHB3; embryonic Kinase 2; Prev. ETK2; Human embryo Kinase 2; Tyro6; EPH-Like Kinase 2; Hek2; EphB3; Tyrosine-Protein Kinase TYRO6; TYRO6; EPH-Like Tyrosine Kinase 2; HEK2; Ephrin Type-B Receptor 3; EPH Receptor B3; EK2
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P705820
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EPHB3; embryonic Kinase 2; Prev. ETK2; Human embryo Kinase 2; Tyro6; EPH-Like Kinase 2; Hek2; EphB3; Tyrosine-Protein Kinase TYRO6; TYRO6; EPH-Like Tyrosine Kinase 2; HEK2; Ephrin Type-B Receptor 3; EPH Receptor B3; EK2
Species:  
Human
Source:  
sf9 insect cells
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Cat. No.: HY-100536
CAS No.: 687561-60-0
Purity:  99.27%
Research Areas:  

Cancer

IWP-3 is a Wnt production inhibitor with an IC50 of 40 nM. IWP-3 also acts as a CK1δ inhibitor, with an IC50 of 1.89 μM against rat full-length CK1δ. IWP-3 inhibits the function of Porcupine (Porcn), thereby blocking the palmitoylation of Wnt proteins, suppressing the canonical Wnt signaling pathway, reducing the proliferative capacity of cancer cells, promoting the differentiation of mesoderm into cardiomyocytes and increasing cardiomyocyte yield. IWP-3 reduces embryonic cell division, alters the cell movement along the anterior-posterior axis of embryos, and causes embryonic shortening. IWP-3 can be used in studies related to cancers such as pancreatic cancer .
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Cat. No.: HY-180814
Research Areas:  

Cancer

SKF-83566-PEG1-pomalidomide is an anti-tumor agent and is formed by the covalent connection of SKF-83566 (HY-103430A) (dopamine D1 receptor antagonist) and Pomalidomide (HY-10984) (immunomodulatory agent). SKF-83566-PEG1-pomalidomide can inhibit cancer cells invasion, migration and colony formation. SKF-83566-PEG1-pomalidomide can inhibit tumor growth and angiogenesis in MDA-MB-231 cell chicken embryo chorioallantoic membrane (CAM) xenograft model. SKF-83566-PEG1-pomalidomide can be used for research of breast cancer .
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Cat. No.: HY-184417
CAS No.: 3085883-97-9
Target:  

Bacterial

Research Areas:  

Infection

Energy-coupling factor-IN-1 is an energy-coupling factor (ECF) transporter inhibitor with an IC50 of 42.84 μM against ECF-FolT2. Energy-coupling factor-IN-1 binds to the interface between the S component and the ECF module, and inhibits the uptake of folic acid and pantothenic acid via the target transporter. Energy-coupling factor-IN-1 acts as a bactericidal agent, exerting rapid and sustained activity for 24 h against Enterococcus faecium, while also acting against Gram-positive bacteria including drug-resistant strains. Energy-coupling factor-IN-1 improves the survival rate of zebrafish embryos infected with Enterococcus faecium. Energy-coupling factor-IN-1 can be used in studies of Gram-positive bacterial infections .
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Cat. No.: HY-B1777AR
CAS No.: 306-67-2
Spermine (tetrahydrochloride) (Standard) is the analytical standard of Spermine (tetrahydrochloride). This product is intended for research and analytical applications. Spermine tetrahydrochloride is a polyamine nitric oxide donor that can provide nitric oxide to platelets and inhibit platelet activation to a certain extent concentration-dependently. Spermine tetrahydrochloride occurs in mammalian tissues, plants, bacteria, ribosomes and bacteriophage. Spermine tetrahydrochloride inhibits primary human embryo lung fibroblasts in vitro. Spermine is a natural antioxidant and anti-inflammatory agent. Spermine is known to inhibit some bacterial cultures, especially strains of Staphylococcus aureus. Spermine induces neurotoxicity in the striarum dose-dependently. Spermine can reversibly inhibits DNA synthetic response, mixed lymphocyte response and the induction of cytolytic lymphocyte response in primary cultures of murine spleen cells .
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Cat. No.: HY-B1777AS
CAS No.: 1173022-85-9
Spermine-d8 (tetrahydrochloride) is the deuterium labeled Spermine tetrahydrochloride. Spermine tetrahydrochloride is a polyamine nitric oxide donor that can provide nitric oxide to platelets and inhibit platelet activation to a certain extent concentration-dependently. Spermine tetrahydrochloride occurs in mammalian tissues, plants, bacteria, ribosomes and bacteriophage. Spermine tetrahydrochloride inhibits primary human embryo lung fibroblasts in vitro. Spermine is a natural antioxidant and anti-inflammatory agent. Spermine is known to inhibit some bacterial cultures, especially strains of Staphylococcus aureus. Spermine induces neurotoxicity in the striarum dose-dependently. Spermine can reversibly inhibits DNA synthetic response, mixed lymphocyte response and the induction of cytolytic lymphocyte response in primary cultures of murine spleen cells .
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Cat. No.: HY-P4184
CAS No.: 550-21-0
Synonyms: (Ser4,Ile8)-Oxytocin
Isotocin is the homologue of mammalian oxytocin in teleost fish, belonging to the category of neurotransmitters/neuromodulators and peripheral hormones. Isotocin exerts biological effects by binding to its homologous isotocin receptor (with EC50 = 1.58e-10 mol/L in gilthead seabream) and specific G-protein-coupled receptor subtypes. Isotocin promotes paternal behavior in cichlids, regulates the expression of Foxi3a and P63, thereby controlling the differentiation of ionocyte progenitor cells and the proliferation of epidermal stem cells, and modulates whole-body ion content in zebrafish embryos. Isotocin regulates social and reproductive behaviors, synchronizes the reproductive cycles of teleost fish, and its neuronal phenotypes can be used to classify the types of reproductive systems in cichlids .
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Cat. No.: HY-P4184A
Synonyms: (Ser4,Ile8)-Oxytocin acetate
Isotocin acetate is the homologue of mammalian oxytocin in teleost fish, belonging to the category of neurotransmitters/neuromodulators and peripheral hormones. Isotocin acetate exerts biological effects by binding to its homologous Isotocin acetate receptor (with EC50 = 1.58e-10 mol/L in gilthead seabream) and specific G-protein-coupled receptor subtypes. Isotocin acetate promotes paternal behavior in cichlids, regulates the expression of Foxi3a and P63, thereby controlling the differentiation of ionocyte progenitor cells and the proliferation of epidermal stem cells, and modulates whole-body ion content in zebrafish embryos. Isotocin acetate regulates social and reproductive behaviors, synchronizes the reproductive cycles of teleost fish, and its neuronal phenotypes can be used to classify the types of reproductive systems in cichlids .
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Cat. No.: HY-114849
CAS No.: 27314-13-2
Purity:  99.94%
Synonyms: SAN 9789
Norflurazon (SAN 9789) is a pre-emergence Herbicide. Norflurazon non-competitively inhibits phytoene desaturase by competing with the enzyme cofactor and disrupts carotenoid biosynthesis, thereby leading to chlorophyll photodegradation and chlorosis. Norflurazon inhibits MGDG synthase, CDP-choline phosphotransferase, Omega-3 FAD7 desaturase, and PG delta-3-trans desaturase, and activates LysoPC-acyltransferase and Omega-3 FAD3 desaturase. Norflurazon inhibits photosynthetic membrane organization, mitochondrial respiration, ATP production, PI3K signaling, and ERK1/2 phosphorylation. Norflurazon activates MAPK P38 phosphorylation and ER stress signaling. Norflurazon induces morphological malformations and cardiovascular effects in zebrafish embryos .
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Cat. No.: HY-159078
CAS No.: 2607139-80-8
Purity:  98.42%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

PolQi1 is a selective inhibitor targeting the Polθ domain of DNA polymerase. PolQi1 inhibits the Polθ-mediated microhomology end joining (TMEJ/alt-EJ) pathway, reducing insertion/deletion (Indels) and imprecise editing events during DNA repair. PolQi1 can enhance the efficiency and accuracy of homology-directed repair (HDR) or Prime editing, and reduce off-target effects; and in combination with DNA-PK inhibitor AZD-7648 (HY-111783), exert efficient genome editing capabilities with dual pathway regulation. PolQi1 can be mainly used in gene editing research (such as CRISPR-Cas9 or Prime editing system optimization) to improve the precision editing efficiency of difficult-to-edit cells (such as primary hepatocytes and mouse embryos) .
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