Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
158 Results for "
DG
" in MedChemExpress (MCE) Product Catalog:
Products (158)
158 Results for "DG" in MCE Product Catalog:
Cat. No.: HY-174329
Target:
Research Areas:
MRT-5702D is a G3BP2 molecular glue degrader. MRT-5702D forms a CRBN-MRT-5702D-G3BP2 ternary complex to activate the ubiquitin-proteasome system for G3BP2 degradation. MRT-5702D can be used for research of G3BP2-related cancers and neurodegenerative diseases .
Cat. No.: HY-189666
CAS No.: 3101978-77-9
KRAS-IN-65 is an orally active KRAS inhibitor. KRAS-IN-65 inhibits KRAS G12D/G12V signaling with IC50 values of 20 nM and 5 nM, respectively. KRAS-IN-65 exhibits reduced glucuronidation and intestinal stability. KRAS-IN-65 produces limited tumor growth inhibition in xenograft models. KRAS-IN-65 can be used for cancer-related research, such as non-small cell lung cancer and colorectal cancer .
Cat. No.: HY-P700908
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DSG3; DSG-3; Desmoglein-3; PVA; CDHF6; DG3
Species:
Human
Source:
HEK293
Cat. No.: HY-13966S2
CAS No.: 201612-55-7
Synonyms: 2-DG-13C; 2-Deoxy-D-arabino-hexose-13C; D-Arabino-2-deoxyhexose-13C
Cat. No.: HY-P83716
Synonyms: 156DAG antibody;
A3a antibody;
AGRNR antibody;
Alpha dystroglycan antibody;
Alpha-DG antibody;
Beta-DG antibody;
Beta-dystroglycan antibody;
DAG antibody;
Dag1 antibody;
DAG1_HUMAN antibody;
Dystroglycan 1 (dystrophin associated glycoprotein 1) antibody;
Dystroglycan antibody;
Dystrophin associated glycoprotein 1 antibody;
Dystrophin-associated glycoprotein 1 antibody;
OTTHUMP00000210857 antibody;
OTTHUMP00000210858 antibody
Cat. No.: HY-164350
CAS No.: 3033690-83-1
KRAS inhibitor-27 (Compound 15h) is the inhibitor for KRAS. KRAS inhibitor-27 inhibits KRAS G12D/G12V mutated cells AsPC-1, SW620 and KRAS wildtype cell HT-29 with IC50 of 378, 0.6 and 3230 nM, respectively. KRAS inhibitor-27 inhibits ERK phosphorylation (IC50 in cell AsPC-1 and SW620 is 0.6 nM and 1 nM), reduces the expression of DUSP4, thereby inhibiting MAPK signaling pathway .
Cat. No.: HY-187519
KRAS-IN-61 is an orally effective pan-KRAS inhibitor that potently inhibits SOS1-mediated KRAS nucleotide exchange (IC50 <10 nM for KRAS G12D/G12V/G12C/WT). KRAS-IN-61 inhibits pERK signaling and cell proliferation in KRAS-mutant tumor cells. KRAS-IN-61 can inhibit tumor growth in vivo. KRAS-IN-61 can be used in studies of KRAS mutation-related cancers, such as colorectal cancer .
Cat. No.: HY-13966S4
CAS No.: 119897-50-6
Synonyms: 2-DG-13C-1; 2-Deoxy-D-arabino-hexose-13C-1; D-Arabino-2-deoxyhexose-13C-1
Cat. No.: HY-178898
CAS No.: 13072-74-7
Cat. No.: HY-D1090
CAS No.: 82855-40-1
Cat. No.: HY-187520
CAS No.: 3137385-11-3
KRAS-IN-62 is an orally effective pan-KRAS inhibitor that potently inhibits SOS1-mediated KRAS nucleotide exchange (IC50 < 10 nM for KRAS G12D/G12V/G12C/WT). KRAS-IN-62 inhibits pERK signaling and cell proliferation in KRAS-mutant tumor cells (pERK IC90 = 0.51 nM in GP2D cells). KRAS-IN-62 inhibits tumor growth in vivo, with plasma concentrations exceeding IC50 for ~20 h after oral administration in beagle dogs. KRAS-IN-62 can be used in studies of KRAS mutation-related cancers, such as colorectal cancer .
Cat. No.: HY-P76301
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DSC2; Desmosomal Glycoprotein III; Prev. DSC3; Desmocollin-3; CDHF2; DGII/III; Cadherin Family Member 2; ARVD11; Desmocollin-2; DG2; Desmosomal Glycoprotein II/III; Desmocollin 2; Desmosomal Glycoprotein II
Species:
Human
Source:
HEK293
Cat. No.: HY-P76302
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DSC2; Desmosomal Glycoprotein III; Prev. DSC3; Desmocollin-3; CDHF2; DGII/III; Cadherin Family Member 2; ARVD11; Desmocollin-2; DG2; Desmosomal Glycoprotein II/III; Desmocollin 2; Desmosomal Glycoprotein II
Species:
Rat
Source:
HEK293
Cat. No.: HY-P76303
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DSC2; Desmosomal Glycoprotein III; Prev. DSC3; Desmocollin-3; CDHF2; DGII/III; Cadherin Family Member 2; ARVD11; Desmocollin-2; DG2; Desmosomal Glycoprotein II/III; Desmocollin 2; Desmosomal Glycoprotein II
Species:
Rat
Source:
HEK293
Cat. No.: HY-P76301A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DSC2; Desmosomal Glycoprotein III; Prev. DSC3; Desmocollin-3; CDHF2; DGII/III; Cadherin Family Member 2; ARVD11; Desmocollin-2; DG2; Desmosomal Glycoprotein II/III; Desmocollin 2; Desmosomal Glycoprotein II
Species:
Human
Source:
HEK293
Cat. No.: HY-159591
CAS No.: 3060515-08-1
YK-8S is a dual-targeted K-Ras (G12D/G12C) covalent inhibitor. YK-8S shows no significant binding to wild-type K-Ras and other mutants (G12R, G13D, Q61R/K). YK-8S exhibits anti-proliferative activity against H358 (G12C) and AGS (G12D) cells. YK-8S inhibits the phosphorylation of p-AKT/p-ERK in BaF3/G12D and G12C cells. YK-8S can be used for pancreatic cancer, colorectal cancer and other tumors with high incidence of G12D .
Cat. No.: HY-P811649
Synonyms: 8-hydroxy-2'-deoxyguanosine; 2'-Deoxy-8-oxoguanosine; 7,8-Dihydro-8-oxo-2'-deoxyguanosine; 8-Oxo-7,8-dihydro-2'-deoxyguanosine; 8-Oxo-7,8-dihydrodeoxyguanosine; 2'-Deoxy-8-oxo-D-guanosine; 8-Oxo-7,8-dihydro-2μ-deoxyguanosine,8-Oxo-DG; 2'-Deoxy-8-hydroxyguanosine;
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
