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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
203 Results for "
IL-8
" in MedChemExpress (MCE) Product Catalog:
Products (203)
203 Results for "IL-8" in MCE Product Catalog:
66
66 Publications Verification
Cat. No.: HY-16711
CAS No.: 182498-32-4
Target:
Research Areas:
SB225002, a potent, selective and non-peptide CXCR2 antagonist, inhibits 125I-IL-8 binding to CXCR2 with an IC50 of 22 nM.
12
12 Cited Publications
Target:
Research Areas:
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells .
8
Research Areas:
8
Research Areas:
7
7 Cited Publications
Cat. No.: HY-P7224
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL8; Lung Giant Cell Carcinoma-Derived Chemotactic Protein; Prev. IL8; Alveolar Macrophage Chemotactic Factor I; MDNCF; Tumor Necrosis Factor-Induced Gene 1; NAP-1; NeutrophIL-Activating Peptide 1; MONAP; T-Cell Chemotactic Factor; GCP-1; Interleukin 8; Monocyte-Derived NeutrophIL Chemotactic Factor; Interleukin-8; Monocyte-Derived NeutrophIL-Activating Peptide; Emoctakin; Granulocyte Chemotactic Protein 1; AMCF-I; Chemokine (C-X-C Motif) Ligand 8; B-ENAP; SCYB8; TSG-1; LYNAP; 3-10C; LUCT; K60; LECT; Small Inducible Cytokine SubfamILy B, Member 8; IL-8; Beta-Thromboglobulin-Like Protein; GCP1; NeutrophIL-Activating Protein 1; NAP1; C-X-C Motif Chemokine 8; NAF; C-X-C Motif Chemokine; Beta Endothelial Cell-Derived NeutrophIL Activating Peptide; Protein 3-10C; C-X-C Motif Chemokine Ligand 8; Lymphocyte Derived NeutrophIL Activating Peptide
Species:
Human
Source:
E. coli
6
Target:
Research Areas:
6-OAU (GTPL5846) (6-n-octylaminouracil) is an GPR84 (G protein-coupled receptor 84) agonist, with an EC50 value of 105 nM. 6-OAU works as a chemoattractant to both PMNs and macrophages, and amplifies the proinflammatory cytokine IL-8, shows proinflammatory function. 6-OAU also displays anti-bacterial function .
6
6 Cited Publications
Target:
Research Areas:
JTE-607, a highly selective inflammatory cytokine synthesis inhibitor, protects from endotoxin shock in mice. JTE-607 inhibits inflammatory cytokine production, including TNF-α, IL-1β, IL-6, IL-8 and IL-10, from LPS-stimulated human PBMCs, with IC50s of 11, 5.9, 8.8, 7.3 and 9.1 nM, respectively . Cleavage and Polyadenylation Specificity Factor 3 (CPSF3) is the target of JTE-607 .
6
6 Cited Publications
Cat. No.: HY-P1110
CAS No.: 185413-30-3
Target:
Research Areas:
5
5 Cited Publications
Cat. No.: HY-N0853
CAS No.: 19885-10-0
4
4 Cited Publications
Cat. No.: HY-P70569
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL8; Lung Giant Cell Carcinoma-Derived Chemotactic Protein; Prev. IL8; Alveolar Macrophage Chemotactic Factor I; MDNCF; Tumor Necrosis Factor-Induced Gene 1; NAP-1; NeutrophIL-Activating Peptide 1; MONAP; T-Cell Chemotactic Factor; GCP-1; Interleukin 8; Monocyte-Derived NeutrophIL Chemotactic Factor; Interleukin-8; Monocyte-Derived NeutrophIL-Activating Peptide; Emoctakin; Granulocyte Chemotactic Protein 1; AMCF-I; Chemokine (C-X-C Motif) Ligand 8; B-ENAP; SCYB8; TSG-1; LYNAP; 3-10C; LUCT; K60; LECT; Small Inducible Cytokine SubfamILy B, Member 8; IL-8; Beta-Thromboglobulin-Like Protein; GCP1; NeutrophIL-Activating Protein 1; NAP1; C-X-C Motif Chemokine 8; NAF; C-X-C Motif Chemokine; Beta Endothelial Cell-Derived NeutrophIL Activating Peptide; Protein 3-10C; C-X-C Motif Chemokine Ligand 8; Lymphocyte Derived NeutrophIL Activating Peptide
Species:
Human
Source:
HEK293
4
Category:
Cardiovascular Disease Flavonols Flavonoids Phenols Polyphenols Plants Other Families Extract Disease Research Fields
Target:
3
3 Cited Publications
Cat. No.: HY-N0314
CAS No.: 28978-02-1
3
3 Cited Publications
Target:
Research Areas:
AP-1/NF-κB activation inhibitor 1 is a potent AP-1 and NF-κB mediated transcriptional activation inhibitor (IC50=1 μM), without blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells .
3
3 Cited Publications
Cat. No.: HY-P7379
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL8; Lung Giant Cell Carcinoma-Derived Chemotactic Protein; Prev. IL8; Alveolar Macrophage Chemotactic Factor I; MDNCF; Tumor Necrosis Factor-Induced Gene 1; NAP-1; NeutrophIL-Activating Peptide 1; MONAP; T-Cell Chemotactic Factor; GCP-1; Interleukin 8
Species:
Human
Source:
CHO
2
2
Research Areas:
N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex .Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells .
1
1 Cited Publications
Cat. No.: HY-P99165
CAS No.: 1036734-93-6
Target:
Research Areas:
1
1 Cited Publications
Target:
Research Areas:
SP-100030 is a potent NF-κB and activator protein-1 (AP-1) double inhibitor (IC50s=50 and 50 nM, respectively). SP-100030 inhibits IL-2, IL-8, and TNF-alpha production in Jurkat and other T cell lines. SP-100030 decreases murine collagen-induced arthritis (CIA) .
1
1 Cited Publications
Cat. No.: HY-P990008
CAS No.: 1365659-05-7
Target:
Research Areas:
1
1 Cited Publications
Synonyms: Boc-Asp(OMe)-FMK
Target:
Research Areas:
Boc-Asp(OME)-Fluoromethyl Ketone is a broad range caspase inhibitor that inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemotactic activity of IL-8 .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
