15 Results for "

5β-Cholanic acid

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "5β-Cholanic acid" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W127512
CAS No.: 546-18-9
Target:  

Drug Intermediate

Research Areas:  

Others

5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems .
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21
21 Publications Verification
Cat. No.: HY-B0172
CAS No.: 434-13-9
Synonyms: 3α-Hydroxy--Cholanic acid
Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is also a FXR antagonist and a PXR/SXR agonist .
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8
8 Cited Publications
Cat. No.: HY-W018512
CAS No.: 4651-67-6
Synonyms: 3α-Hydroxy-7-oxo--Cholanic acid
7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion .
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2
2 Cited Publications
Cat. No.: HY-B0172S
CAS No.: 83701-16-0
Synonyms: 3α-Hydroxy--Cholanic acid-d4
Lithocholic acid-d4 is the deuterium labeled Lithocholic acid, which is a toxic secondary bile acid .
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1
1 Cited Publications
Cat. No.: HY-B0172B
CAS No.: 1534-35-6
Synonyms: 3β-Hydroxy--Cholanic acid; 3-Epilithocholic acid; β-Lithocholic acid
Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate .
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Cat. No.: HY-B0172R
CAS No.: 434-13-9
Synonyms: 3α-Hydroxy--Cholanic acid (Standard)
Lithocholic acid (Standard) is the analytical standard of Lithocholic acid. This product is intended for research and analytical applications. Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is also a FXR antagonist and a PXR/SXR agonist .
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Cat. No.: HY-177795
CAS No.: 6868-73-1
Synonyms: 3,6-Diketo-LCA
Target:  

Drug Derivative

Research Areas:  

Others

5β-Cholanic acid-3,6-dione (3,6-Diketo-LCA) is a similar substance to Lithocholic acid (LCA) (HY-B0172). 5β-Cholanic acid-3,6-dione cannot activate the Vitamin D receptor (VDR), and can be used as a negative control for studying the relationship between LCA derivatives and VDR .
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Cat. No.: HY-W018512R
CAS No.: 4651-67-6
Synonyms: 3α-Hydroxy-7-oxo--Cholanic acid (Standard)
7-Ketolithocholic acid (Standard) is the analytical standard of 7-Ketolithocholic acid. This product is intended for research and analytical applications. 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion .
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Cat. No.: HY-W747313
CAS No.: 859-97-2
Synonyms: -Cholanic acid-3,7-dione; 3,7-Dioxo--cholanoic acid; 3,7-Diketochenodeoxycholic acid
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Dehydrochenodeoxycholic acid is a ketone bile acid .
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Cat. No.: HY-W127512R
CAS No.: 546-18-9
Research Areas:  

Others

5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems .
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Cat. No.: HY-W127586
CAS No.: 7753-72-2
5β-Cholanic acid 3,7-dione methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-W587978
CAS No.: 71883-64-2
Synonyms: Lagocholic acid; 3α,7α,12β-Trihydroxy--Cholanic acid
12β-Hydroxyisocholic acid (Lagocholic acid) is a bile acid isomer that can be used in the study of bile acid metabolism .
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Cat. No.: HY-B0172S1
CAS No.: 52840-06-9
Synonyms: 3α-Hydroxy--Cholanic acid-d5
Lithocholic acid-d5 is deuterium labeled Lithocholic acid.
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Cat. No.: HY-B0172BR
CAS No.: 1534-35-6
Synonyms: 3β-Hydroxy--Cholanic acid (Standard); 3-Epilithocholic acid (Standard); β-Lithocholic acid (Standard)
Isolithocholic acid (Standard) is the analytical standard of Isolithocholic acid. This product is intended for research and analytical applications. Isolithocholic acid (β-Lithocholic acid) is an isomer of Lithocholic acid. Isolithocholic acid, a bile acid, is formed by microbial metabolism of Lithocholic acid or Lithocholic acid 3α-sulfate[1][2].
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Cat. No.: HY-129123R
CAS No.: 1610516-67-0
Research Areas:  

Infection

7-Ketolithocholic acid (Standard) is the analytical standard of 7-Ketolithocholic acid. This product is intended for research and analytical applications. 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion .
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