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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
AICAR
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "AICAR" in MCE Product Catalog:
226
226 Publications Verification
Synonyms: Acadesine; AICA Riboside
Category:
Human Gut Microbiota Metabolites Natural Products Endogenous metabolite Disease Research Fields Cancer
Target:
226
226 Publications Verification
Synonyms: Acadesine phosphate; AICA Riboside phosphate
Target:
1
1 Cited Publications
Cat. No.: HY-P2048
CAS No.: 1627580-64-6
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology
1
1 Cited Publications
Research Areas:
ATIC-IN-1 (compound 14) acetate is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM, whcich catalyzes de novo purine biosynthesis. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 acetate exhibits anti-tumor activity via reduction in cell numbers and cell division rates .
1
1 Cited Publications
Cat. No.: HY-P2048A
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology
Category:
Human Gut Microbiota Metabolites Other Diseases Endogenous metabolite Disease Research Fields
Target:
Synonyms: 5-Formamidoimidazole-4-carboxamide ribotide
Category:
Target:
Cat. No.: HY-29244
CAS No.: 67095-44-7
Target:
Research Areas:
ATIC-IN-2 (Compound 1) is a competitive inhibitor for the bifunctional enzyme AICAR Tfase/IMPCH (ATIC), that binds to inosine monophosphate cyclohydrolase (IMPCH) with a Ki of 0.13 μM .
Cat. No.: HY-13417AR
CAS No.: 681006-28-0
Synonyms: Acadesine phosphate (Standard); AICA Riboside phosphate (Standard)
Category:
Cat. No.: HY-RS01156
Target:
Research Areas:
ATIC Human Pre-designed siRNA Set A contains three designed siRNAs for ATIC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-150252
CAS No.: 1402453-15-9
ATIC-IN-1(compound 14) is an inhibitor targeting to Aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC) dimerization with a Ki value of 685 nM. ATIC dimerization is crucial for its aminoimidazole carboxamide ribonucleotide (AICAR) transformylase activity. ATIC-IN-1 exhibits anti-tumor activity via reduction in cell numbers and cell division rates .
Cat. No.: HY-13417S
CAS No.: 1609374-70-0
Synonyms: Acadesine-13C2,15N; AICA Riboside-13C2,15N
Cat. No.: HY-14526
CAS No.: 118252-44-1
Synonyms: 543U76; 5,11-Methenyltetrahydrohomofolate
Target:
Research Areas:
5-DACTHF (543U76) is an inhibitor of purine de novo biosynthesis. 5-DACTHF is a GAR-TFase and AICAR-TFase inhibitor (IC50: 3 and 94 μM). 5-DACTHF is a potent antitumor agent .
Cat. No.: HY-P85553
Synonyms: 5 aminoimidazole 4 carboxamide 1 beta D ribonucleotide transformylase/inosinicase; 5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase; 5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; AICAR; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR transformylase; AICARFT; AICARFT/IMPCHASE; ATIC; Bifunctional purine biosynthesis protein PURH; FLJ93545; IMP cyclohydrolase; IMP synthase; IMP synthetase; IMPCHASE; Inosinicase; OK/SW-cl.86; Phosphoribosylaminoimidazolecarboxamide formyltransferase; Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PUR9_HUMAN; PURH.
Cat. No.: HY-P810469
Synonyms: ATIC, 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase, PURH, IMPCHASE, AICARFT, Phosphoribosylaminoimidazolecarboxamide Formyltransferase/IMP Cyclohydrolase, AICAR Transformylase/Inosine Monophosphate Cyclohydrolase, Bifunctional Purine Biosynthesis Protein ATIC, 5-Aminoimidazole-4-Carboxamide-1-Beta-D-Ribonucleotide Transformylase/Inosinicase, AICAR Formyltransferase/IMP Cyclohydrolase Bifunctional Enzyme, Epididymis Secretory Sperm Binding Protein Li 70p, Bifunctional Purine Biosynthesis Protein PURH, AICARFT/IMPCHASE, HEL-S-70p, AICAR
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
