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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
Anti-breast cancer
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "Anti-breast cancer" in MCE Product Catalog:
10
10 Publications Verification
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OPN-IN-1 is an osteopontin (OPN) expression inhibitor. OPN-IN-1 has potential anti-breast cancer cell metastasis activity and can be used in the study of cancer .
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4 Cited Publications
Cat. No.: HY-N2025
CAS No.: 57396-78-8
Category:
Flavonoids Flavones Metabolic Disease Plants Bignoniaceae Extract Oroxylum indicum (Linn.) Bentham ex Kurz Disease Research Fields
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1
1 Cited Publications
Synonyms: STX64; BN83495; 667-Coumate
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Irosustat is a potent steroid sulfatase inhibitor, with an IC50 of 8 nM, and exhibits anti-breast cancer activity.
1
1 Cited Publications
Cat. No.: HY-N2124
CAS No.: 174972-79-3
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FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect .
Cat. No.: HY-108692
CAS No.: 78473-71-9
Category:
Human Gut Microbiota Metabolites Microorganisms Lignans Phenylpropanoids Endogenous metabolite Disease Research Fields Cancer
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Cat. No.: HY-W088191
CAS No.: 619-57-8
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4-Hydroxybenzamide is an amide and intermediate. 4-Hydroxybenzamide can be isolated from the herb Berberis pruinosa. 4-Hydroxybenzamide derivatives exhibit anti-breast cancer activity. 4-Hydroxybenzamide can be used in atherosclerosis research .
Cat. No.: HY-L074
3,404 compounds
Breast cancer is the most frequent cancer among women, impacting 2.1 million women each year, and also causes the greatest number of cancer-related deaths among women. Surgery is usually the first type of treatment for breast cancer, which is usually followed by chemotherapy or radiotherapy or, in some cases, hormone or targeted therapies, especially for metastatic breast cancer (MBC).
Breast cancer is a heterogeneous disease, which is categorized into 3 major subtypes based on the presence or absence of molecular markers for estrogen or progesterone receptors and human epidermal growth factor 2 (ERBB2; formerly HER2): hormone receptor positive/ERBB2 negative (70% of patients), ERBB2 positive (15%-20%), and triple-negative (tumors lacking all 3 standard molecular markers; 15%). Different intrinsic subtypes exhibit different tumor behavior with different prognoses, and may require specific targeted therapies to maximize treatment effectiveness. Otherwise, some signaling pathways also play important roles in the development of breast cancer, such as NF-κB Signaling Pathway, TGF-beta Signaling Pathway, PI3K/AKT/mTOR signaling pathway and Notch Signaling Pathway. These signaling pathways offer ideal targets for development of new targeted therapies for breast cancer.
MCE supplies a unique collection of 3,404 compounds with identified and potential anti-breast cancer activity. MCE Anti-Breast Cancer Compound Library is a useful tool for anti-breast cancer drugs screening.
Cat. No.: HY-175845
CAS No.: 2787582-78-7
Research Areas:
Scr-IN-2 is an effective c-Scr inhibitor with an IC50 of 302 nM. Scr-IN-2 exhibits nanomolar-level anti-breast cancer activity. Scr-IN-2 increases the level of ROS in cells, induces mitochondrial damage, G1 phase arrest, and apoptosis. Scr-IN-2 can be used in the research of breast cancer .
Cat. No.: HY-108692R
CAS No.: 78473-71-9
Cat. No.: HY-175846
CAS No.: 2822560-46-1
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TQFL13 is derivative of Thymoquinone (TQ) (HY-D0803) with potent anti-breast cancer activity. TQFL13 exhibits higher cytotoxicity against breast cancer cells (BT549, MDA-MB-231, 4T1). TQFL13 increases apoptosis and blocks the cell cycle at S and G2/G1 phases in breast cancer cells. TQFL13 shows dose-dependent anti-tumor efficacy in mouse breast cancer allograft model. TQFL13 can be used for the study of breast cancer .
Cat. No.: HY-P10686
CAS No.: 503027-61-0
Cat. No.: HY-107309
CAS No.: 17233-22-6
Category:
Triterpenes Terpenoids Anemone raddeana Regel Plants Disease Research Fields Pulsatilla chinensis (Bunge) Regel Cancer Ranunculaceae Extract
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Cat. No.: HY-151116
CAS No.: 1059177-03-5
HER2-IN-10 is a psoralen derivative. HER2-IN-10 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-10 induces apoptosis .
Cat. No.: HY-157487
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Anticancer agent 185 (compound 9d) is a glycohybrid derivative of pyrazolopyrimidine [1,5-a]. Anticancer agent 185 has good anti-breast cancer activity. Anticancer agent 185 shows good cytotoxic activity against MCF-7 cells with IC50 value of 15.3 μM .
Cat. No.: HY-W778286
CAS No.: 918502-72-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
