39 Results for "

B7.1

" in MedChemExpress (MCE) Product Catalog:
Products (39)

39 Results for "B7.1" in MCE Product Catalog:

69
69 Cited Publications
Cat. No.: HY-B1618
CAS No.: 50-22-6
Synonyms: 17-Deoxycortisol; 11β,21-Dihydroxyprogesterone; Kendall's compound B
Corticosterone (17-Deoxycortisol) is an orally active and adrenal cortex-produced glucocorticoid, which plays an important role in regulating neuronal functions of the limbic system (including hippocampus, prefrontal cortex, and amygdala). Corticosterone increases the Rab-mediated AMPAR membrane traffic via SGK-induced phosphorylation of GDI. Corticosterone also interferes with the maturation of dendritic cells and shows a good immunosuppressive effect .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P84266
Synonyms: B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1

Host:  

Mouse

Application:  

IHC-P, FC, ELISA

Reactivity:  

Human, Mouse, Rat, Rabbit

loading...
    loading...
Cat. No.: HY-102090
CAS No.: 635324-72-0
Purity:  99.81%
Target:  

CD28

Research Areas:  

Inflammation/Immunology

B7/CD28 interaction inhibitor 1 (copmound 6b) is a potent B7.1-CD28 interaction inhibitor with an IC50 of 50 nM .
loading...
    loading...
Cat. No.: HY-P990127

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD80/B7-1 Antibody (RM80) is an anti-mouse CD80/B7-1 IgG2a monoclonal antibody. Anti-Mouse CD80/B7-1 Antibody (RM80) can inhibit the number of tissue-resident memory (TRM) cells. Anti-Mouse CD80/B7-1 Antibody (RM80) can prolong the survival time of transplants combined with CD86 mAb. Anti-Mouse CD80/B7-1 Antibody (RM80) can be used for researches on inflammation conditions and immunology such as viral myocarditis and corneal transplant .
loading...
    loading...
Cat. No.: HY-161633
CAS No.: 3034244-71-5
Target:  

PROTACs EGFR FAK

Research Areas:  

Cancer

PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor (EGFR), with DC50 <100 nM. PROTAC EGFR degrader 11 binds CRBN-DDB1 with a Ki of 36 nM. PROTAC EGFR degrader 11 degrades EGFR, focal adhesion kinase (FAK), and RSK1, inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 <100 nM.
loading...
    loading...
Cat. No.: HY-P990986
CAS No.: 2922216-49-5

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Efdelikofusp alfa is a bispecific Fc fusion protein. Efdelikofusp alfa is formed by fusing the N-terminal extracellular domain of human CD80 (B7.1) with the Fc fragment of human immunoglobulin G4 (IgG4), and is linked to an interleukin-2 variant (IL-2v) as the C-terminal part. Efdelikofusp alfa exhibits potential immunostimulatory, immune checkpoint inhibitory, and antitumor activities.
loading...
    loading...
Cat. No.: HY-P990992
CAS No.: 2922216-50-8
Synonyms: GI-102

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Efzilonkofusp alfa is a bispecific Fc fusion protein. Efzilonkofusp alfa is formed by fusing the N-terminal extracellular domain of human CD80 (B7.1) with the Fc fragment of human immunoglobulin G4 (IgG4), and is linked to an interleukin-2 variant (IL-2v) as the C-terminal part. Efzilonkofusp alfa exhibits potential immunostimulatory, immune checkpoint inhibitory, and antitumor activities.
loading...
    loading...
Cat. No.: HY-P990128

Target:  

CD28

Research Areas:  

Inflammation/Immunology Cancer

Anti-Rat CD80/B7-1 Antibody (3H5) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to rat CD80/B7-1. Anti-Rat CD80/B7-1 Antibody (3H5) blocks a costimulatory signals for T-cell activation. Anti-Rat CD80/B7-1 Antibody (3H5) can be used for the researches of cancer and immunology .
loading...
    loading...
Cat. No.: HY-P991356
Synonyms: LAE-005

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

FAZ-053 is a human monoclonal antibody (mAb) targeting B7-H1/PD-L1/CD274. FAZ-053 inhibits the interaction of PD-L1 with PD-1 and B7-1 on monocytes, dendritic cells, and B cells. FAZ-053 enhances interleukin 2 production. FAZ-053 can be used in advanced alveolar soft tissue sarcoma (ASPS), chordoma, and triple-negative breast cancer research .
loading...
    loading...
Cat. No.: HY-P78382
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD80 molecule; B7; B71; B7-1; BB1; CD28LG1; CD80; B7.1; CD28LG1; LAB7
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P704983
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD80 molecule; B7; B71; B7-1; BB1; CD28LG1; CD80; B7.1; CD28LG1; LAB7
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78063
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: CD80 molecule; B7; B71; B7-1; BB1; CD28LG1; CD80; B7.1; CD28LG1; LAB7
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P84266A
Synonyms: B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1

Host:  

Mouse

Application:  

IHC-P, FC, ELISA

Reactivity:  

Human, Mouse, Rat, Rabbit

loading...
    loading...
Cat. No.: HY-G0006R
CAS No.: 73590-85-9
Synonyms: Ufiprazole (Standard)
Research Areas:  

Others

Omeprazole sulfide (Standard) is the analytical standard of Omeprazole sulfide. This product is intended for research and analytical applications. Omeprazole sulfide is an Esomeprazole (HY-17021) precursor. Omeprazole sulfide can be converted to Esomeprazole by Lysinibacillus sp. B71. Esomeprazole can inhibit gastric H +/ + ATP enzyme. Omeprazole sulfide is mainly used in gastroesophageal reflux disease, gastric ulcer and antibacterial research .
loading...
    loading...
Cat. No.: HY-RS02269
Research Areas:  

Others

CD80 Human Pre-designed siRNA Set A contains three designed siRNAs for CD80 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS16921
Research Areas:  

Others

Cd80 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd80 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-169281
Target:  

COX

Research Areas:  

Infection

Antiviral agent 61 (compound Z40) is a potent antiviral agent. Antiviral agent 61 shows anti tomato spotted wilt virus (TSWV) activity with an EC50 value of 252 μg/mL. Antiviral agent 61 increases the RNA expression of Ndufb9,COX6B,7.1.2.2,E,COX5B,Ndufs4,and SDHB,decreases the RNA expression of Ndufb7,Ndufa5,and G .
loading...
    loading...
Cat. No.: HY-P72768
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: T-lymphocyte activation antigen CD80; Activation B7-1 antigen; B7; CD80
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P72767
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: T-lymphocyte activation antigen CD80; Activation B7-1 antigen; B7; CD80
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P85804
Synonyms: T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD antigen CD80;

Host:  

Mouse

Application:  

FC, ELISA

Reactivity:  

Human

loading...
    loading...