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BA

" in MedChemExpress (MCE) Product Catalog:

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By Research Areas:	Cancer (86) Cardiovascular Disease (14) Endocrinology (3) Infection (35) Inflammation/Immunology (14) Metabolic Disease (15) Neurological Disease (24)
Click Chemistry:	Azide (1)
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183

Inhibitors & Agonists

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Inhibitory Antibodies

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17360

Tiotropium Bromide 2 Publications Verification BA679 BR	mAChR	Neurological Disease
Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.

HY-104010

Asciminib 10+ Cited Publications ABL001	Bcr-Abl	Cancer
Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC₅₀ of 0.25 nM .

HY-18960

CHZ868 5+ Cited Publications	JAK	Cancer
CHZ868 is a type II JAK2 inhibitor with an IC₅₀ of 0.17 μM in EPOR JAK2 WT Ba/F3 cell.

HY-108742

Abaloparatide 3 Publications Verification BA 058; BIM 44058	PTHR Arrestin	Metabolic Disease Cancer
Abaloparatide (BA 058) is a parathyroid hormone receptor 1 (PTHR1) analog. Abaloparatide also is a selective PTHR1 activator. Abaloparatide enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide enhances bone formation and cortical structure in mice. Abaloparatide has the potential for the research of osteoporosis .

HY-41700

D-Alanine (R)-Alanine; BA 2776; D-α-Alanine	Endogenous Metabolite	Neurological Disease
D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC₅₀ of 9 mM for GlyR .

HY-104010A

Asciminib hydrochloride 10+ Cited Publications ABL001 hydrochloride	Bcr-Abl	Cancer
Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC₅₀ of 0.25 nM .

HY-15125

(R)-(+)-Bay-K-8644 1 Publications Verification	Calcium Channel	Cardiovascular Disease
(R)-(+)-Bay-K-8644 is a calcium channel inhibitor. (R)-(+)-Bay-K-8644 inhibits Ba ²⁺ currents (I_Ba) (IC₅₀=975 nM).

HY-162596

NRL-1049 BA-1049 free BAse	ROCK	Neurological Disease
NRL-1049 (BA-1049 (free base)) is an orally available and selective ROCK2 inhibitor with IC₅₀ values of 0.59 µM for ROCK2 and 26 µM for ROCK1, respectively. NRL-1049 modulates ROCK signaling, preserves blood-brain barrier integrity, reduces edema, seizures and hemorrhage, and alleviates cerebral cavernous malformation lesion burden. NRL-1049 can be used for the study of acute brain injury, ischemic stroke, and cerebral cavernous malformations .

HY-145626

Ozuriftamab 1 Publications Verification BA302	ADC Antibody ROR	Cancer
Ozuriftamab is a human IgG1 kappa antibody of ROR2. Ozuriftamab can be used to synthesize ADC such as Ozuriftamab vedotin (HY-145627). Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-N0539

Calceolarioside B	Aldose Reductase SARS-CoV Interleukin Related	Infection Inflammation/Immunology Cancer
Calceolarioside B is a phenylethanoid glycoside. Calceolarioside B can be isolated from the leaves of Akebia quinata. Calceolarioside B inhibits RLAR activity with an IC₅₀ value of 23.99 μM. Calceolarioside B inhibits the entry of Omicron BA.2 into host cells. Calceolarioside B reduces IL-6 levels. Calceolarioside B has immunomodulatory activity. Calceolarioside B has anticancer activity against human hormone-independent prostate cancer .

HY-B1486

Oxprenolol hydrochloride 1 Publications Verification BA 39089	Adrenergic Receptor	Cardiovascular Disease
Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a K_i of 7.10 nM in a radioligand binding assay using rat heart muscle .

HY-103370

Talniflumate BA 7602-06	Chloride Channel	Inflammation/Immunology
Talniflumate (BA 7602-06) is the proagent of Niflumic acid (HY-B0493), exerting its activity in the body through conversion to niflumic acid by esterase . Talniflumate is an orally active Ca ²⁺-activated Cl ^- channel (CaCC) blocker. Talniflumate can be used as an analgesic and anti-inflammatory agent in cystic fibrosis mouse model of distal intestinal obstructive syndrome .

HY-118384

Sangivamycin 3 Publications Verification NSC 65346; BA-90912	PKC Nucleoside Antimetabolite/Analog	Cancer
Sangivamycin (NSC 65346), a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an K_i of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers .

HY-B2006

Fenvalerate	Environmental Pollutants Phosphatase Bacterial	Infection
Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC₅₀ of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide .

HY-B0460

Tiotropium bromide monohydrate 2 Publications Verification BA-679 BR monohydrate	mAChR	Neurological Disease
Tiotropium bromide (BA-679 BR) monohydrate is a long-acting muscarinic receptor antagonist .

HY-N0309

Soyasaponin Ba 1 Publications Verification	Aldose Reductase	Metabolic Disease
Soyasaponin Ba is a soyasaponin isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitors (ARI) .

HY-W099602

Dodecane BA 51-090453	Biochemical Assay Reagents TNF Receptor	Metabolic Disease
Dodecane (Ba 51-090453) is an ester product. Dodecane is an aliphatic hydrocarbon. Dodecane can result in a high TNF-α expression and transepidermal waterloss (TEWL) .

HY-110173

TC-G 1005	G protein-coupled Bile Acid Receptor 1	Metabolic Disease
TC-G 1005 is a potent, selective and orally active agonist of the BA receptor Takeda G protein-coupled receptor 5 (TGR5), with EC₅₀s of 0.72 and 6.2 nM for hTGR5 and mTGR5, respectively. TC-G 1005 can reduce glucose levels in vivo .

HY-17360S1

Tiotropium-d6 bromide BA679 BR-d₆	Isotope-Labeled Compounds mAChR	Neurological Disease
Tiotropium-d₆ (bromide) is deuterium labeled Tiotropium (Bromide). Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.

HY-41700S

D-Alanine-d3 (R)-Alanine-d₃; BA 2776-d₃; D-α-Alanine-d₃	Isotope-Labeled Compounds Endogenous Metabolite	Others
D-Alanine-d₃ is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

HY-134877

BAY 2476568	EGFR ERK Akt	Cancer
BAY 2476568 is a potent and mutant-selective inhibitor targeting EGFR exon20 insertion variants. BAY 2476568 potently inhibits the kinase activity of EGFR exon20 insertion mutants (insASV, insSVD, insNPG) with IC₅₀ values of 0.09 nM, 0.21 nM, and 0.11 nM, respectively. BAY 2476568 inhibits EGFR (Y1068) phosphorylation and reduces the phosphorylation of ERK1/2 and Akt (S473) in Ba/F3 cells expressing EGFR exon20 insertion mutants (insASV, insSVD). BAY 2476568 can be used for the study of non-small cell lung cancer (NSCLC) driven by EGFR exon20 insertion mutations .

HY-P1423A

BA 1 TFA	Bombesin Receptor	Metabolic Disease Cancer
BA 1 TFA is a potent agonist for the bombesin (BB) family of receptors. BA1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC₅₀s of 6, 0.4, 2.5 nM .

HY-108742A

Abaloparatide TFA 3 Publications Verification BA 058 TFA; BIM 44058 TFA	Arrestin PTHR	Metabolic Disease Endocrinology Cancer
Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue. Abaloparatide TFA also is a selective PTHR1 activator. Abaloparatide TFA enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide TFA enhances bone formation and cortical structure in mice. Abaloparatide TFA has the potential for the research of osteoporosis .

HY-145627

Ozuriftamab vedotin BA3021; Anti-ROR2 ADC; CAB-ROR2-ADC	Antibody-Drug Conjugates (ADCs) Microtubule/Tubulin	Cancer
Ozuriftamab vedotin (BA3021), an antibody-drug conjugate (ADC), is a conditionally active biologic (CAB) anti-receptor tyrosine kinase orphan receptor 2 (ROR2) humanized monoclonal antibody Ozuriftamab (HY-145626) conjugated to VcMMAE (HY-15575). Ozuriftamab vedotin has antitumor activities .

HY-145622

Mecbotamab vedotin BA3011; CAB-Axl-ADC; CAB-anti-Axl-ADC	Antibody-Drug Conjugates (ADCs) TAM Receptor	Cancer
Mecbotamab vedotin (BA3011) is a pH dependent antibody drug conjugate (ADC) targeting AXL. Mecbotamab vedotin can significantly inhibit AXL in DU145 cells and LCLC-103H cells and kills cells. Mecbotamab vedotin can be used for research on cancer such as lung cancer, pancreatic cancer and prostate cancer. The antibody component is Mecbotamab (HY-P9988), and the ADC toxin molecule is Monomethyl auristatin E (MMAE) (HY-15162) .

HY-114314

BA-53038B	HBV	Infection
BA-53038B is a HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly. BA-53038B has antiviral activity for hepatitis B virus (HBV) with an EC₅₀ value of 3.32 μM. BA-53038B can be used for the research of chronic hepatitis B .

HY-126432

NRL-1049 dihydrochloride BA-1049	ROCK	Neurological Disease
NRL-1049 dihydrochloride (BA-1049) is a selective and orally active rho-associated protein kinase 2 (ROCK2) inhibitor with an IC₅₀ of 0.59 μM. NRL-1049 dihydrochloride shows selectivity for ROCK2 is 44 times that of ROCK1 (IC₅₀ = 26 μM). NRL-1049 dihydrochloride can preserve the blood-brain barrier after acute injury .

HY-P9988

Mecbotamab BA301	ADC Antibody TAM Receptor	Cancer
Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE (HY-15162) via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011) .

HY-12083

PPY-A	Bcr-Abl	Cancer
PPY-A is a potent T315I mutant and wild-type Abl kinases inhibitor with IC₅₀s of 9 and 20 nM, respectively. PPY-A inhibits Ba?F3 cells transformed with wild-type Abl and Abl T315I mutantl with IC₅₀s of 390 and 180 nM, respectively. PPY-A can be used for the research of chronic myeloid leukemia (CML) .

HY-174368

PROTAC EML4-ALK Degrader-1 Pro-BA	PROTACs Apoptosis Anaplastic lymphoma kinase (ALK)	Cancer
PROTAC EML4-ALK Degrader-2 (Pro-BA) is a selective and orally active linker-free EML4-ALK PROTAC degrader with the DC₅₀ of 74 nM in H1322 cells (T_1/2 = 8 h). PROTAC EML4-ALK Degrader-2 relies on GID4 and proteasome pathways to promote ubiquitination of target proteins, leading to cell apoptosis. PROTAC EML4-ALK Degrader-2 can be used for research on cancer. (Pink: EML4-ALK Ligand (HY-40114); Blue: GID4 Ligand (HY-150908))

HY-164397

XMU-MP-5	Anaplastic lymphoma kinase (ALK) Apoptosis	Cancer
XMU-MP-5 is a selective inhibitor for ALK. XMU-MP-5 inhibits ALK-mutated Ba/F3 cell with IC₅₀s of 4-50 nM, and induces apoptosis in EML4-ALK Ba/F3. XMU-MP-5 exhibits antitumor efficacy in mice .

HY-41700S1

D-Alanine-d4 (R)-Alanine-d₄; BA 2776-d₄; D-α-Alanine-d₄	Endogenous Metabolite	Others
D-Alanine-d₄ is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

HY-120577

BA 41899	Calcium Channel	Cardiovascular Disease
BA 41899 is a purely calcium-sensitizing agent. BA 41899 is completely devoid of phosphodiesterase (PDE) III inhibitory activity or any other known inotropic mechanism. BA 41899 can be used for the research of cardiovascular diseases, such as congestive heart failure (CHF) .

HY-RS05607

GP1BA Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
GP1BA Human Pre-designed siRNA Set A contains three designed siRNAs for GP1BA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

GP1BA Human Pre-designed siRNA Set A GP1BA Human Pre-designed siRNA Set A

HY-U00007

Stilbamidine BA 2652; StilBAmidin	Fungal	Infection Cancer
Stilbamidine is a diamidine compound derived from Stilbene and used chiefly in the form of its crystalline isethionate salt in treating various fungal infections.

HY-129982

SC-435	Apical Sodium-Dependent Bile Acid Transporter	Metabolic Disease
SC-435 is an orally effective apical sodium codependent bile acid transporter (ASBT) inhibitor. SC-435 effectively removes neurotoxic bile acids and ammonia from the blood by inhibiting intestinal ASBT, thereby alleviating liver and brain damage caused by liver failure. SC-435 can alter hepatic cholesterol metabolism and lower plasma low-density lipoprotein-cholesterol concentrations .

HY-N10443

Mammea A/BA	Parasite Apoptosis Autophagy Reactive Oxygen Species (ROS)	Infection
Mammea A/BA has potent activity against Trypanosoma cruzi (T. cruzi). Mammea A/BA induces mitochondrial dysfunction, reactive oxygen species (ROS) production and DNA fragmentation, and increases number of acidic vacuoles. Mammea A/BA can induce apoptosis, autophagy and necrosis. Mammea A/BA can be used for researching chagas disease .

HY-P1423

BA 1	Bombesin Receptor	Metabolic Disease Cancer
BA 1 is a potent agonist for the bombesin (BB) family of receptors. BA 1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC₅₀s of 6, 0.4, 2.5 nM .

HY-B1486A

Oxprenolol BA 39089 free BAse	Adrenergic Receptor	Cardiovascular Disease
Oxprenolol (Ba 39089 free base) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a K_i of 7.10 nM in a radioligand binding assay using rat heart muscle .

HY-B1486S

Oxprenolol-d7 hydrochloride BA 39089-d₇	Adrenergic Receptor	Cardiovascular Disease
Oxprenolol-d₇ (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a K_i of 7.10 nM in a radioligand binding assay using rat heart muscle .

HY-17360S

Tiotropium-d3 bromide BA679 BR-d₃	Isotope-Labeled Compounds mAChR	Neurological Disease
Tiotropium-d₃ (bromide) is the deuterium labeled Tiotropium (Bromide). Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.

HY-U00007A

Stilbamidine dihydrochloride 1 Publications Verification BA 2652 dihydrochloride; StilBAmidin dihydrochloride	Fungal	Infection Cancer
Stilbamidine dihydrochloride is a diamidine compound derived from Stilbene and used chiefly in the form of its crystalline isethionate salt in treating various fungal infections.

HY-41700S5

D-Alanine-13C3 (R)-Alanine-¹³C₃; BA 2776-¹³C₃; D-α-Alanine-¹³C₃	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
D-Alanine- ¹³C₃ ((R)-Alanine- ¹³C₃) is the ¹³C-labeled D-Alanine (HY-41700). D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC₅₀ of 9 mM for GlyR .

HY-N0309R

Soyasaponin Ba (Standard)	Reference Standards Aldose Reductase	Metabolic Disease
Soyasaponin Ba (Standard) is the analytical standard of Soyasaponin Ba. This product is intended for research and analytical applications. Soyasaponin Ba is a soyasaponin isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitors (ARI) .

HY-145871

BA38017	HBV	Infection
BA38017 is a potent HBV core protein assembly modulator. BA38017 inhibits HBV replication with an EC₅₀ of 0.20 μM .

HY-A0171A

Benzoctamine hydrochloride BA-30803	5-HT Receptor	Neurological Disease
Benzoctamine hydrochloride (Ba-30803) is a psychoactive agent with anti-anxiety effect. Benzoctamine hydrochloride blocks the central postsynaptic serotonin receptors and decreases 5-HT turnover in the brain .

HY-121726

3HOI-BA-01	mTOR Autophagy	Cardiovascular Disease
3HOI-BA-01 is amTORinhibitor.3HOI-BA-01reduces infarct size and inducedautophagyin a murine myocardial ischemia/reperfusion injury model .

HY-R01674

hsa-miR-548ba mimic	MicroRNA	Cancer
hsa-miR-548ba mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-548ba mimic hsa-miR-548ba mimic

HY-170605

BA-AZT1	HBV	Infection
BA-AZT1 is the inhibitor for HBV polymerase and sodium taurocholate cotransporting polypeptide (NTCP). BA-AZT1 inhibits the secretion of viral capsid protein HBsAg and HBeAg with IC₅₀ of 0.65 µM and 13.42 µM, inhibits the HBV DNA replication with an IC₅₀ of 0.70 µM .

HY-163735

BA6b9	Potassium Channel	Cardiovascular Disease
BA6b9 is an allosteric inhibitor of SK4 channels that targets the CaM–PIP2-binding domain with a IC₅₀ value of 8.6 µM (WT SK4). BA6b9 inhibits SK4 channels by interacting with two specific residues, Arg191 and His192 in the S4–S5 linker. BA6b9 significantly prolongs atrial and atrioventricular effective refractory period (ERP) and reduces atrial fibrillation (AF) induction in rat isolated hearts, which has the potential to be used for the research of arrhythmia .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-13434

Ionomycin Maximum Cited Publications 120 Publications Verification SQ23377	Infection Microorganisms Classification of Application Fields Antibiotics Disease Research Anticancer Disease Research Fields Other Antibiotics Source Classification	Calcium Channel PKC Bacterial Apoptosis Antibiotic
Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC) .

HY-13434A

Ionomycin calcium Maximum Cited Publications 120 Publications Verification SQ23377 calcium	Infection Microorganisms Classification of Application Fields Antibiotics Disease Research Anticancer Disease Research Fields Other Antibiotics Source Classification	Calcium Channel PKC Bacterial Apoptosis Antibiotic
Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC) .

HY-41700

D-Alanine (R)-Alanine; BA 2776; D-α-Alanine	Structural Classification Microorganisms Classification of Application Fields Anti-aging Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC₅₀ of 9 mM for GlyR .

HY-N0539

Calceolarioside B	Classification of Application Fields Simple Phenylpropanols Akebia quinata (Houttuyn) Decaisne Lardizabalaceae Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields Source Classification Cancer	Aldose Reductase SARS-CoV Interleukin Related
Calceolarioside B is a phenylethanoid glycoside. Calceolarioside B can be isolated from the leaves of Akebia quinata. Calceolarioside B inhibits RLAR activity with an IC₅₀ value of 23.99 μM. Calceolarioside B inhibits the entry of Omicron BA.2 into host cells. Calceolarioside B reduces IL-6 levels. Calceolarioside B has immunomodulatory activity. Calceolarioside B has anticancer activity against human hormone-independent prostate cancer .

HY-77995

2-Methoxybenzaldehyde o-Anisaldehyde	Infection Microorganisms Cinnamomum cassia (L.) D. Don Classification of Application Fields Ketones, Aldehydes, Acids Plants Lauraceae Disease Research Fields Source Classification	Bacterial Fungal
2-Methoxybenzaldehyde (o-Anisaldehyde) is a bacterial/fungal inhibitor with a *BA₅₀* value of 0.19 for Salmonella. 2-Methoxybenzaldehyde can be used for the study of bacterial and fungal infectious diseases .

HY-118384

Sangivamycin 3 Publications Verification NSC 65346; BA-90912	Natural Products Microorganisms Classification of Application Fields Disease Research Fields Cancer Source Classification	PKC Nucleoside Antimetabolite/Analog
Sangivamycin (NSC 65346), a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an K_i of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers .

HY-N0309

Soyasaponin Ba 1 Publications Verification	Triterpenes Classification of Application Fields Leguminosae Glycine max (L.) merr Terpenoids Metabolic Disease Plants Disease Research Fields Source Classification	Aldose Reductase
Soyasaponin Ba is a soyasaponin isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitors (ARI) .

HY-N10443

Mammea A/BA	other families Coumarins Phenylpropanoids Plants Calophyllum brasiliense auct. non Camb. Source Classification	Parasite Apoptosis Autophagy Reactive Oxygen Species (ROS)
Mammea A/BA has potent activity against Trypanosoma cruzi (T. cruzi). Mammea A/BA induces mitochondrial dysfunction, reactive oxygen species (ROS) production and DNA fragmentation, and increases number of acidic vacuoles. Mammea A/BA can induce apoptosis, autophagy and necrosis. Mammea A/BA can be used for researching chagas disease .

HY-N0309R

Soyasaponin Ba (Standard)	Triterpenes Structural Classification Leguminosae Glycine max (L.) merr Terpenoids Plants Source Classification	Reference Standards Aldose Reductase
Soyasaponin Ba (Standard) is the analytical standard of Soyasaponin Ba. This product is intended for research and analytical applications. Soyasaponin Ba is a soyasaponin isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitors (ARI) .

HY-41700R

D-Alanine (Standard) (R)-Alanine (Standard); BA 2776 (Standard); D-α-Alanine (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
D-Alanine (Standard) is the analytical standard of D-Alanine. This product is intended for research and analytical applications. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR .

HY-N15784

Tauro-12-oxolithocholanoic acid sodium	Lipid	Biochemical Assay Reagents
Tauro-12-oxolithocholanoic acid sodium is a bile acid (BA) suitable to investigate BAs and their relatives’ behavior and correlation with liver, gallbladder, and bile ducts diseases.

HY-N0539R

Calceolarioside B (Standard)	Structural Classification Simple Phenylpropanols Akebia quinata (Houttuyn) Decaisne Lardizabalaceae Phenols Polyphenols Phenylpropanoids Plants Source Classification	Aldose Reductase Reference Standards SARS-CoV Interleukin Related
Calceolarioside B (Standard) is the analytical standard of Calceolarioside B (HY-N0539). This product is intended for research and analytical applications. Calceolarioside B is a phenylethanoid glycoside. Calceolarioside B can be isolated from the leaves of Akebia quinata. Calceolarioside B inhibits RLAR activity with an IC₅₀ value of 23.99 μM. Calceolarioside B inhibits the entry of Omicron BA.2 into host cells. Calceolarioside B reduces IL-6 levels. Calceolarioside B has immunomodulatory activity. Calceolarioside B has anticancer activity against human hormone-independent prostate cancer .

HY-N4080

Cyclobuxine D	other families Classification of Application Fields Plants Disease Research Fields Inflammation/Immunology Steroids Source Classification	mAChR
Cyclobuxine D is a steroidal alkaloid extracted from Buxus microphylla. Cyclobuxine D has a significant bradycardic effect in the rat heart and an inhibitory action on acetylcholine and Ba ⁺⁺−induced contraction of the longitudinal muscle isolated from the rabbit jejunum .

HY-118384R

Sangivamycin (Standard) NSC 65346 (Standard); BA-90912 (Standard)	Natural Products Microorganisms Source Classification	Reference Standards PKC Nucleoside Antimetabolite/Analog
Sangivamycin (Standard) is the analytical standard of Sangivamycin. This product is intended for research and analytical applications. Sangivamycin (NSC 65346), a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an Ki of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers[1][2].

HY-W008226R

Phloracetophenone (Standard) 2,4,6-trihydroxyacetophenone (Standard); 1-(2,4,6-Trihydroxyphenyl)ethanone (Standard)	Structural Classification other families Ketones, Aldehydes, Acids Phenols Polyphenols Plants Source Classification Curcuma comosa Roxb. Zingiberaceae	Reference Standards Cytochrome P450 Bacterial Antibiotic
Oxprenolol (hydrochloride) (Standard) is the analytical standard of Oxprenolol (hydrochloride). This product is intended for research and analytical applications. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle .

HY-77995R

2-Methoxybenzaldehyde (Standard) o-Anisaldehyde (Standard)	Structural Classification Microorganisms Cinnamomum cassia (L.) D. Don Ketones, Aldehydes, Acids Plants Lauraceae Source Classification	Reference Standards Bacterial Fungal
2-Methoxybenzaldehyde (Standard) is the analytical standard of 2-Methoxybenzaldehyde. This product is intended for research and analytical applications. 2-Methoxybenzaldehyde (o-Anisaldehyde) is a bacterial/fungal inhibitor with a BA50 value of 0.19 for Salmonella. 2-Methoxybenzaldehyde can be used for the study of bacterial and fungal infectious diseases .

HY-N19852

Mammea E/BA	Structural Classification Mammea americana L. Coumarins Phenylpropanoids Plants Calophyllaceae Source Classification	Biochemical Assay Reagents
Mammea E/BA is a prenylated coumarin anticancer agent that can be isolated from the seeds of Mammea americana. Mammea E/BA scavenges DPPH free radicals. Mammea E/BA induces cytotoxicity in colon cancer cells. Mammea E/BA can be used for the research of colon cancer .

HY-N17781

3-O-Acetyl-11-methoxy-α-boswellic acid 3-Acetyl-11-methoxy-α-BA	Triterpenes Structural Classification Boswellia ovalifoliolata N.P.Balakr. & A.N.Henry Terpenoids Plants Burseraceae Source Classification	Others
3-O-Acetyl-11-methoxy-α-boswellic acid (3-Acetyl-11-methoxy-α-BA) is a triterpenoid α-boswellic acid derivative with potential anti-inflammatory and antitumor activity, which can be isolated from frankincense of the Boswellia genus.

HY-N15790

Deoxycholic acid disulfate sodium	Lipid	Drug Derivative
Deoxycholic acid disulfate sodium is a bile acid (BA).

HY-W587458

Deoxycholic acid 3-sulfate disodium	Triterpenes Structural Classification Terpenoids Endogenous metabolite Source Classification	Drug Metabolite
Deoxycholic acid 3-sulfate disodium is a steroid bile salt, a sulfate derivative of the bile acid (BA) deoxycholic acid.

HY-N15827

Glyco-ω-muricholanoic acid	Lipid	Endogenous Metabolite
Glyco-ω-muricholanoic acid is an endogenous metabolite and a glycine conjugated bile acid (BA) of ω-Muricholanoic Acid.

HY-N15768

Tauro-3β,5α,6β-trihydroxycholanoic acid sodium	Lipid	Biochemical Assay Reagents
Tauro-3β,5α,6β-trihydroxycholanoic acid sodium is a bile acid (BA) suitable to investigate BAs and their relatives’ behavior and correlation with liver, gallbladder, and bile ducts diseases.

Cat. No.	Product Name	Chemical Structure

HY-17360S1

Tiotropium-d6 bromide
Tiotropium-d₆ (bromide) is deuterium labeled Tiotropium (Bromide). Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.

HY-41700S

D-Alanine-d3
D-Alanine-d₃ is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

HY-41700S1

D-Alanine-d4
D-Alanine-d₄ is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

HY-B1486AS

Oxprenolol-d7
Oxprenolol-d₇ is the deuterium labeled Oxprenolol. Oxprenolol (Ba 39089 free base) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a K_i of 7.10 nM in a radioligand binding assay using rat heart muscle .

HY-B1486S

Oxprenolol-d7 hydrochloride
Oxprenolol-d₇ (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a K_i of 7.10 nM in a radioligand binding assay using rat heart muscle .

HY-17360S

Tiotropium-d3 bromide
Tiotropium-d₃ (bromide) is the deuterium labeled Tiotropium (Bromide). Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.

HY-41700S5

D-Alanine-13C3
D-Alanine- ¹³C₃ ((R)-Alanine- ¹³C₃) is the ¹³C-labeled D-Alanine (HY-41700). D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC₅₀ of 9 mM for GlyR .

HY-126432S

(Rac)-NRL-1049-d5 dihydrochloride
(Rac)-NRL-1049-d₅ dihydrochloride ((Rac)-BA-1049-d5) is deuterated labeled (Rac)-NRL-1049.

HY-B2006S

Fenvalerate-d5
Fenvalerate-d₅ is the deuterium labeled Fenvalerate. Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC₅₀ of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide .

HY-41700S3

D-Alanine-d7
D-Alanine-d₇ is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR.

HY-41700S2

D-Alanine-d1
D-Alanine-d is the deuterium labeled D-Alanine. D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC₅₀ of 9 mM for GlyR .

HY-B0549S

Flavoxate-d5

Flavoxate-d₅ is deuterium labeled Flavoxate. Flavoxate hydrochloride (Rec-7-0040; DW61) is an orally active L-type Ca ²⁺ channel inhibitor and antispasmodic. Flavoxate hydrochloride inhibits cyclic adenosine monophosphate production by blocking voltage-dependent inward Ba ²⁺ currents, regulating the brainstem micturition center, and stimulating G protein-coupled receptors. Consequently, Flavoxate hydrochloride induces relaxation of bladder smooth muscle and inhibits isovolumetric rhythmic contractions. Flavoxate hydrochloride effectively increases bladder capacity and alleviates symptoms of urgent urination frequency and pollakiuria caused by overactive bladder. Flavoxate hydrochloride can be used in research on overactive bladder and related voiding dysfunctions .

HY-B0549AS

Flavoxate-d4 hydrochloride

Flavoxate-d₄ hydrochloride (Rec-7-0040-d₄) is the deuterium labeled Flavoxate hydrochloride. Flavoxate hydrochloride (Rec-7-0040; DW61) is an orally active L-type Ca ²⁺ channel inhibitor and antispasmodic. Flavoxate hydrochloride inhibits cyclic adenosine monophosphate production by blocking voltage-dependent inward Ba ²⁺ currents, regulating the brainstem micturition center, and stimulating G protein-coupled receptors. Consequently, Flavoxate hydrochloride induces relaxation of bladder smooth muscle and inhibits isovolumetric rhythmic contractions. Flavoxate hydrochloride effectively increases bladder capacity and alleviates symptoms of urgent urination frequency and pollakiuria caused by overactive bladder. Flavoxate hydrochloride can be used in research on overactive bladder and related voiding dysfunctions .

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