274 Results for "

BA

" in MedChemExpress (MCE) Product Catalog:
Products (274)

274 Results for "BA" in MCE Product Catalog:

132
132 Publications Verification
Cat. No.: HY-13434
CAS No.: 56092-81-0
Purity:  99.27%
Synonyms: SQ23377
Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC) .
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132
132 Publications Verification
Cat. No.: HY-13434A
CAS No.: 56092-82-1
Purity:  98.02%
Synonyms: SQ23377 calcium
Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC) .
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16
16 Cited Publications
Cat. No.: HY-104010
CAS No.: 1492952-76-7
Purity:  99.61%
Synonyms: ABL001
Target:  

Bcr-Abl

Research Areas:  

Cancer

Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM .
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16
16 Cited Publications
Cat. No.: HY-104010A
CAS No.: 2119669-71-3
Purity:  99.84%
Synonyms: ABL001 hydrochloride
Target:  

Bcr-Abl

Research Areas:  

Cancer

Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM .
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9
9 Cited Publications
Cat. No.: HY-15124
CAS No.: 98625-26-4
Purity:  99.10%
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

(S)-(-)-Bay-K-8644 is an agonist of L-type Ca 2+ channel. (S)-(-)-Bay-K-8644 activates Ba 2+ currents (IBa) (EC50=32 nM).
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7
7 Cited Publications
Cat. No.: HY-18960
CAS No.: 1895895-38-1
Target:  

JAK

Research Areas:  

Cancer

CHZ868 is a type II JAK2 inhibitor with an IC50 of 0.17 μM in EPOR JAK2 WT Ba/F3 cell.
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4
4 Cited Publications
Cat. No.: HY-13491
CAS No.: 1033769-28-6
Purity:  99.44%
Target:  

Trk Receptor

Research Areas:  

Cancer

GNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) .
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3
3 Cited Publications
Cat. No.: HY-108742
CAS No.: 247062-33-5
Purity:  99.91%
Synonyms: BA 058; BIM 44058
Target:  

PTHR Arrestin

Research Areas:  

Metabolic Disease Cancer

Abaloparatide (BA 058) is a parathyroid hormone receptor 1 (PTHR1) analog. Abaloparatide also is a selective PTHR1 activator. Abaloparatide enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide enhances bone formation and cortical structure in mice. Abaloparatide has the potential for the research of osteoporosis .
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3
3 Cited Publications
Cat. No.: HY-118384
CAS No.: 18417-89-5
Purity:  97.68%
Synonyms: NSC 65346; BA-90912
Sangivamycin (NSC 65346), a nucleoside analog, is a potent inhibitor of protein kinase C (PKC) with an Ki of 10 μM. Sangivamycin has potent antiproliferative activity against a variety of human cancers .
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3
3 Cited Publications
Cat. No.: HY-108742A
Purity:  99.86%
Synonyms: BA 058 TFA; BIM 44058 TFA
Target:  

Arrestin PTHR

Research Areas:  

Metabolic Disease Endocrinology Cancer

Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue. Abaloparatide TFA also is a selective PTHR1 activator. Abaloparatide TFA enhances Gs/cAMP signaling and β-arrestin recruitment. Abaloparatide TFA enhances bone formation and cortical structure in mice. Abaloparatide TFA has the potential for the research of osteoporosis .
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3
3 Cited Publications
Cat. No.: HY-11007
CAS No.: 778270-11-4
Purity:  99.82%
Research Areas:  

Cancer

GNF-2 is a highly selective, allosteric, non-ATP competitive inhibitor of Bcr-Abl. GNF-2 inhibits Ba/F3.p210 proliferation with an IC50 of 138 nM .
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3
3 Cited Publications
Cat. No.: HY-125845
CAS No.: 1448297-52-6
Purity:  99.09%
Synonyms: VH032-NH2; VHL ligand 1
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

(S,R,S)-AHPC (VH032-NH2) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 μM in Ba/F3 cells .
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2
2 Cited Publications
Cat. No.: HY-17360
CAS No.: 136310-93-5
Synonyms: BA679 BR
Target:  

mAChR

Research Areas:  

Inflammation/Immunology

Tiotropium bromide (BA-679 BR) is a long-acting anticholinergic bronchodilator. Tiotropium bromide blocks the action of acetylcholine at muscarinic M1, M2, and M3 receptors, prevents bronchoconstriction, and dilates bronchial airways. Tiotropium bromide is applicable to research related to chronic obstructive pulmonary disease and asthma .
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2
2 Cited Publications
Cat. No.: HY-15125
CAS No.: 98791-67-4
Purity:  97.80%
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

(R)-(+)-Bay-K-8644 is a calcium channel inhibitor. (R)-(+)-Bay-K-8644 inhibits Ba 2+ currents (IBa) (IC50=975 nM).
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2
2 Cited Publications
Cat. No.: HY-B0460
CAS No.: 411207-31-3
Synonyms: BA-679 BR monohydrate
Target:  

mAChR

Research Areas:  

Inflammation/Immunology

Tiotropium bromide monohydrate (BA-679 BR monohydrate) is a long-acting anticholinergic bronchodilator. Tiotropium bromide monohydrate blocks the action of acetylcholine at muscarinic M1, M2, and M3 receptors, prevents bronchoconstriction, and dilates bronchial airways. Tiotropium bromide monohydrate is applicable to research related to chronic obstructive pulmonary disease and asthma .
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2
2 Cited Publications
Cat. No.: HY-P86463
Synonyms: LHR antibody; BA-1 antibody; CD 44 antibody; CD44 antibody; CD44 antigen antibody; CD44 molecule; Indian blood group; antibody; CD44 molecule antibody; CD44_HUMAN antibody; CDw44 antibody; CDW44 antigen antibody; Cell surface glycoprotein CD44 antibody; chondroitin sulfate proteoglycan 8 antibody; CSPG8 antibody; ECMR-III antibody; Epican antibody; Extracellular matrix receptor III antibody; GP90 lymphocyte homing/adhesion receptor antibody

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-145626
CAS No.: 2460399-44-2
Purity:  99.73%
Synonyms: BA302

Target:  

ADC Antibodies ROR

Research Areas:  

Cancer

Ozuriftamab is a human IgG1 kappa antibody of ROR2. Ozuriftamab can be used to synthesize ADC such as Ozuriftamab vedotin (HY-145627). Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
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1
1 Cited Publications
Cat. No.: HY-N0539
CAS No.: 105471-98-5
Calceolarioside B is a phenylethanoid glycoside. Calceolarioside B can be isolated from the leaves of Akebia quinata. Calceolarioside B inhibits RLAR activity with an IC50 value of 23.99 μM. Calceolarioside B inhibits the entry of Omicron BA.2 into host cells. Calceolarioside B reduces IL-6 levels. Calceolarioside B has immunomodulatory activity. Calceolarioside B has anticancer activity against human hormone-independent prostate cancer .
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1
1 Cited Publications
Cat. No.: HY-B1486
CAS No.: 6452-73-9
Synonyms: BA 39089
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle .
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1
1 Cited Publications
Cat. No.: HY-N0309
CAS No.: 114590-20-4
Soyasaponin Ba is a soyasaponin that can be isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitor (ARI). Soyasaponin Ba activates Akt/GSK3β/β-catenin signaling pathway, reduces lipid accumulation, lowers ROS generation, improves mitochondrial membrane potential, ATP levels, and morphology, and inhibits apoptosis. Soyasaponin Ba can be used for the research of lipid accumulation and secondary diabetic complications .
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