23 Results for "

Bel-7402 cells

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "Bel-7402 cells" in MCE Product Catalog:

Cat. No.: HY-N11928
CAS No.: 136040-44-3
Changnanic acid (schisandrin) is a triterpene compound with potential anti-tumor effects. Changnanic acid exhibits moderate cytotoxic activity against human tumor cell lines Bel-7402, MCF-7 and HL-60, with IC50s of 100 μM, 100 μM and 50.51 μM respectively .
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Cat. No.: HY-N7980
CAS No.: 2170211-22-8
Rubipodanone A, a naphthohydroquinone dimer, shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells. Rubipodanone A also shows obvious activating effect at 20 and 40 μM for NF-κB .
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Cat. No.: HY-177269
CAS No.: 2648988-92-3
Target:  

Arf Family GTPase

Research Areas:  

Cancer

CHNQD-01269, a brefeldin A-cinnamate derivative, is an Arf1 inhibitor. CHNQD-01269 exhibits potent cytotoxic activity against HepG2 and BEL-7402 cells, with IC50 values of 0.29 and 0.84 μM, respectively. CHNQD-01269 is indicated for hepatocellular carcinoma (HCC) research .
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Cat. No.: HY-144253
Target:  

Akt ERK

Research Areas:  

Cancer

AKT-IN-11 is one of the most effective antibacterial agents against human hepatoma BEL-7402 cell line with an IC50 value of 1.15μM.
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Cat. No.: HY-155695
Target:  

HDAC

Research Areas:  

Cancer

HDAC-IN-61 (compound 12k) is a potent and orally active HDAC inhibitor. HDAC-IN-61 has anticancer active with an IC50 value of 30 nM for Bel-7402 cell. HDAC-IN-61 can be used in research of cancer .
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Cat. No.: HY-N7623
CAS No.: 989-72-0
Target:  

Drug Derivative

Research Areas:  

Cancer

Ursonic acid methyl ester is an esterified derivative of Ursolic acid (HY-N0140). Ursonic acid methyl ester shows growth inhibitory activity against four tumor cell lines, HL-60, BGC, Bel-7402 and Hela with ED50 values of >100 µg/ml .
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Cat. No.: HY-146467
CAS No.: 2413148-58-8
Target:  

Drug Derivative

Research Areas:  

Cancer

Anticancer agent 62 (compound 4c) is a potent anticancer agent. Anticancer agent 62 shows antiproliferative activity in HepG2, Bel-7402 and MCF-7 cancer cells, with IC50 values of 0.019, 0.060 and 0.016 μM, respectively. Anticancer agent 62 shows effective tumor growth inhibition .
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Cat. No.: HY-146466
CAS No.: 2413148-53-3
Target:  

Others

Research Areas:  

Cancer

Anticancer agent 61 (compound 3v) is an orally active and potent anticancer agent. Anticancer agent 61 shows antiproliferative activity in HepG2, Bel-7402 and MCF-7 cancer cells, with IC50 values of 1.12, 1.97 and 1.08 μM, respectively. Anticancer agent 61 shows effective tumor growth inhibition .
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Cat. No.: HY-N12128
CAS No.: 1418183-25-1
Ophiopogonin R (compound 3) is a steroid saponin. Ophiopogonin R was isolated and purified from natural ophiopogonin. Ophiopogonin R was not cytotoxic to five human tumor cell lines (HepG2, HLE, BEL7402, BEL7403 and Hela) .
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Cat. No.: HY-N12253
CAS No.: 16763-48-7
(19R)-13-Deoxy-19-hydroxyenmein is the parent compound of enmein-type diterpenoid analogs. (19R)-13-Deoxy-19-hydroxyenmein has anti-proliferative activities with IC50 values of 0.41, 0.85, 0.43, 1.89 μM against human cancer cell lines K562, MGC-803, CaEs-17, and Bel-7402, respectively .
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Cat. No.: HY-N21592
CAS No.: 1628026-28-7
12α-Hydroxymeliatoosenin I is a limonoid compound found in the roots of Trichilia sinensis. In the MTT assay, 12α-Hydroxymeliatoosenin I exhibits no significant growth inhibitory activity against K562, SGC-7901, and BEL-7402 cells, with all IC50 values exceeding 40 μM. 12α-Hydroxymeliatoosenin I is applicable to studies related to limonoid natural products and tumor cell growth .
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Cat. No.: HY-N7535
CAS No.: 96801-92-2
Chlorovaltrate K is a chlorinated valepotriate with anticancer effects. Chlorovaltrate K shows moderate cytotoxicity against A549, PC-3M, HCT-8 and Bel 7402 cell lines with IC50 values of 2.32-8.26 μM .
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Cat. No.: HY-N13081
CAS No.: 6869-66-5
Target:  

Others

3-Oxo-cinobufagin (compound 8) is a potential anticancer compound that can be isolated from the broth of M. spinosus by high-performance liquid chromatography. Compared to other isolated compounds, the hydroxyl group at the C-5 position of 3-Oxo-cinobufagin is further oxidized or isomerized, significantly reducing its cytotoxic activity against most cell lines (except HEL), while increasing its activity against the BEL cell line. The IC50 values of 3-Oxo-cinobufagin's cytotoxicity against cancer cells are: 71.3 μM (HepG2), 90.2 μM (SMMC-7221), 0.11 μM (BEL-7402), 72.5 μM (K562), 5.3 μM (HL-60), and 12 nM (HEL) .
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Cat. No.: HY-177268
CAS No.: 2673232-30-7
Research Areas:  

Cancer

CHNQD-01426 (Compound 4a) is an anticancer agent. CHNQD-01426 has cytotoxic activities against cancer cells. CHNQD-01426 significantly inhibits hepatocellular carcinoma cells proliferation via arresting S and G2/M phase cell cycle and induces apoptosis by inducing ROS production and elevating apoptosis-related proteins expression. CHNQD-01426 potently inhibits tumor growth in HepG2 xenograft mice model .
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Cat. No.: HY-N21864
CAS No.: 1303438-53-0
Cathayanon J is a flavanone natural product with 2R configuration, which is found in the stem bark of Morus cathayana. Cathayanon J exhibits weak cytotoxicity against A549, Bel 7402, BGC-823, HCT-8 and A2780 human cancer cells, with IC50 values of 4.67, 5.95, 6.70, 5.86 and 5.79 μg/mL, respectively. Cathayanon J can be used in cancer-related research .
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Cat. No.: HY-N18292
CAS No.: 1802143-09-4
Qinanone G is a 2-(2-phenylethyl)chromone (HY-N8220) derivative found in the high quality Chinese agarwood 'Qi-Nan' from Aquilaria sinensis (Lour.) Glig. Qinanone G shows no inhibitory activity against AChE and cancer cells .
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Cat. No.: HY-N18174
CAS No.: 1373246-40-2
Glaucogenin E is a C21 steroid sapogenin found in rhizomes of Cynanchum stauntonii (Decne.) Schltr. ex Levl. Glaucogenin E shows no cytotoxic activity against human cancer cells .
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Cat. No.: HY-N17995
CAS No.: 1386988-84-6
GypenosideZ-3 is a dammarane triterpene glycoside found in the roots of Machilus yaoshansis .
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Cat. No.: HY-N21970
CAS No.: 89200-00-0
Mulberrofuran F is a Diels-Alder type adduct. Mulberrofuran F exerts antihypertensive effects, exhibits cytotoxicity against human cancer cells, and inhibits the growth of Gram-positive bacteria. Mulberrofuran F can be used in studies related to hypertension and cancer .
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Cat. No.: HY-D3106
CAS No.: 2659241-66-2
Target:  

Fluorescent Dye

Research Areas:  

Others

Lys-VBOD is a Fluorescent probe for lysosomal viscosity monitoring and live cell imaging. Its detection mechanism depends on viscosity: increased viscosity restricts the twisting of the double bond between the indole and BODIPY fluorophore, as well as the rotation of the single bond between quinoline and BODIPY, which reduces non-radiative decay and leads to enhanced fluorescence intensity in high viscosity environments; it also features a morpholine group that provides lysosome-targeting properties, allowing it to localize to lysosomes for viscosity detection. The probe has excitation/emission wavelengths of Ex/Em = 602/637 nm, and its fluorescence intensity shows a good linear relationship with log-transformed viscosity values. Lys-VBOD is stable across a wide pH range of 5.35 to 10.74, is not affected by macromolecules and proteins like BSA, has a fluorescence lifetime that increases with viscosity, and can visualize real-time lysosomal viscosity changes in live cells under Dexamethasone (HY-14648) stimulation[1].
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