16 Results for "

CCL11

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "CCL11" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N2609
CAS No.: 2196-14-7
7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid, which can be isolated from Glycyrrhiza uralensis. 7,4'-Dihydroxyflavone is eotaxin/CCL11 inhibitor and CBR1 inhibitor (IC50=0.28 μM). 7,4'-Dihydroxyflavone has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production . 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2.7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 µM .
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1
1 Cited Publications
Cat. No.: HY-103361
CAS No.: 58816-69-6
Purity:  99.86%
Target:  

CCR

Research Areas:  

Neurological Disease Endocrinology

SB297006 is a CCR3 antagonist, which significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells.
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Cat. No.: HY-P99474
CAS No.: 375348-49-5
Synonyms: CAT 213; iCo-008

Target:  

CCR

Research Areas:  

Inflammation/Immunology

Bertilimumab (CAT 213; iCo-008) is a human monoclonal antibody targeting eotaxin-1 (CCL11). Bertilimumab has the potential for allergic disorders research .
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Cat. No.: HY-110295
CAS No.: 688347-51-5
Target:  

GSNOR

Research Areas:  

Inflammation/Immunology

SPL-334 is a potent and selective S-Nitrosoglutathione reductase (GSNOR) inhibitor. SPL-334 causes a significant reduction in the production of Th2 cytokines IL-5 and IL-13 and the levels of the chemokine CCL11 (eotaxin-1) in the airways. SPL-334 can be used in research of allergic airway inflammation .
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Cat. No.: HY-RS02081
Research Areas:  

Others

CCL11 Human Pre-designed siRNA Set A contains three designed siRNAs for CCL11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16897
Research Areas:  

Others

Ccl11 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccl11 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23339
Research Areas:  

Others

Ccl11 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccl11 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-174771
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CCL11 mRNA encodes the human C-C motif chemokine ligand 11 (CCL11) protein, a member of the CC subfamily. CCL11 is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
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Cat. No.: HY-N2609R
CAS No.: 2196-14-7
7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid, which can be isolated from Glycyrrhiza uralensis. 7,4'-Dihydroxyflavone is eotaxin/CCL11 inhibitor and CBR1 inhibitor (IC50=0.28 μM). 7,4'-Dihydroxyflavone has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production . 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2.7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 µM .
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Cat. No.: HY-111198
CAS No.: 887647-69-0
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

YM-355179 fumarate is a newly synthesized selective CCR3 antagonist with the potential to inhibit eosinophil-related allergic inflammatory diseases. YM-355179 can effectively inhibit the binding of CCL11 and CCL5 to CCR3-expressing cells, with IC50 values of 7.6 nM and 24 nM respectively. In functional experiments, YM-355179 can inhibit CCL11-induced intracellular Ca(2+) influx, chemotaxis and eosinophil degranulation, IC50 The values are 8.0 nM, 24 nM and 29 nM respectively .
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Cat. No.: HY-P700285
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL11; SCYA11Eotaxin; C-C motif chemokine 11; Small-inducible cytokine A11
Species:  
Source:  
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Cat. No.: HY-P71901
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL11; Scya11Eotaxin; C-C motif chemokine 11; Eosinophil chemotactic protein; Small-inducible cytokine A11
Species:  
Rat
Source:  
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Cat. No.: HY-P811052
Synonyms: Scya11, CCL11, Eotaxin, C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P7159
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuEotaxin/CCL11; C-C motif chemokine 11; Eosinophil chemotactic protein; SCYA11
Species:  
Source:  
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Cat. No.: HY-P7160
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuEotaxin/CCL11; C-C motif chemokine 11; Eosinophil chemotactic protein; SCYA11
Species:  
Source:  
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Cat. No.: HY-P700963
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Eotaxin; C-C motif chemokine 11; Small-inducible cytokine A11; SCYA11; eotaxin-1
Species:  
Source:  
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