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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
Colo320
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "Colo320" in MCE Product Catalog:
Cat. No.: HY-P10925
CAS No.: 3044032-95-0
Synonyms: FOG-001; I-66
OM-153 is a potent and orally active tankyrase inhibitor with IC50s of 13 nM and 2 nM for tankyrase 1 and tankyrase 2 (TNKS1/2), respectively. OM-153 inhibits luciferase-based Wnt/β-catenin signaling reporter activity with an IC50 value of 0.63 nM. OM-153 shows inhibition of Wnt/β-catenin signaling and proliferation in COLO 320DM .
Category:
Ketones, Aldehydes, Acids Valeriana officinalis Linn. Plants Valerianaceae Disease Research Fields Cancer
Target:
Cat. No.: HY-N8491
CAS No.: 38049-26-2
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Cat. No.: HY-149366
CAS No.: 2986412-70-6
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ABCB1-IN-1 (compound 3) is a potent ABCB1 inhibitor. ABCB1-IN-1 induces cell apoptosis. ABCB1-IN-1 bearing 1-benzylimidazole has IC50 values of 1.26 μM and 2.21 μM for Colo205 and Colo320 cells, respectively .
Cat. No.: HY-P10994
CAS No.: 1988684-26-9
Synonyms: Eps8(327-335)
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Cat. No.: HY-143897
CAS No.: 2762767-56-4
PIM1-IN-3 (Compound HL8) is a potent inhibitor of PIM1. PIM1-IN-3 shows selective inhibition for the PIM-1 enzyme. PIM1-IN-3 induces apoptosis efficiently in Colo320 cells. PIM1-IN-3 has the potential for the research of cancer diseases .
Cat. No.: HY-N10363
CAS No.: 162062-88-6
Category:
Triterpenes Juglandaceae Terpenoids Cyclocarya paliurus (Batal.) Iljinsk. Plants Disease Research Fields Cancer
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Cat. No.: HY-N4282
CAS No.: 19492-03-6
Category:
Alkekengi officinarum var. franchetii (Mast.) R.J.Wang Other Diseases Coumarins Phenylpropanoids Plants Solanaceae Disease Research Fields
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Cat. No.: HY-168925
EXQ-2d is the inhibitor for tankyrase and inhibits TNKS1 and TNKS2 with an IC50 of 48.8 nM and 13.8 nM (pIC50=7.31 and 7.86). EXQ-2d inhibits WNT/β-catenin signaling pathway with IC50 of 515 nM. EXQ-2d exhibits anti-proliferative activity in cancer cells COLO 320DM and RKO with GI50 of 4.9 μM and 77 μM .
Cat. No.: HY-P10995
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Synonyms: 4-Desacetylvinblastine; Desacetylvincaleukoblastine
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Desacetylvinblastine (4-Desacetylvinblastine) is the major metabolite of Vinblastine (HY-13780) and a cytotoxic agent. When used alone, desacetylvinblastine has poor anti-tumor effects, but it can exert significant anti-tumor activity when in the presence of specific conjugates .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
