19 Results for "

Dectin-1

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "Dectin-1" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
2
2 Cited Publications
Cat. No.: HY-131166
CAS No.: 54724-00-4
Purity:  98.5%
Curdlan is a polysaccharide found in bacteria, consisting of a glucose homopolymer with β-1,3-glycosidic linkages [1]. Curdlan can be recognized by Dectin-1 (a C-type lectin receptor), inducing immune responses in tissue mast cells and enhancing dendritic cell effects in tumor immunity. Curdlan holds potential for research in cancer and immune-inflammatory diseases [1] .
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2 Cited Publications
Cat. No.: HY-119109
CAS No.: 9008-22-4
Purity:  ≥98.0%
Laminaran is an β-1-3-glucan and a typical ligand for Dectin-1 from Eisenia Bicyclis, has potent immunomodulating, radioprotective, and anticancer activities [1]. Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds . Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy .
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1 Cited Publications
Cat. No.: HY-139413
CAS No.: 9041-22-9
Purity:  99.00%
β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery [1]. β-d-glucan is an enteric delivery vehicle for probiotics .
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1 Cited Publications
Cat. No.: HY-P70101
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuC-type lectin domain family 7 member A/Dectin-1, Fc; Beta-glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; Dectin1; Dectin-1; Dectin1CANDF4
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Cat. No.: HY-134816
CAS No.: 9012-72-0
Purity:  ≥96.0%
D-Glucan is an orally effective Dectin-1 receptor immune activator with antioxidant properties (reducing TNF-α). D-Glucan activates macrophages and neutrophils to scavenge free radicals, inhibit oxidative stress and inflammatory responses, and improve insulin sensitivity. D-Glucan promotes glycolysis by enhancing the activity of the antioxidant enzyme glutathione, inhibiting gluconeogenesis and activating GK. D-Glucan can be used in the research of liver damage protection (antagonizing Acetaminophen (HY-66005) toxicity), radiation protection (synergistic with vitamin E) and diabetes (improving glucose metabolism) [1] .
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Cat. No.: HY-147295
CAS No.: 53238-80-5
Synonyms: BTH 1677; Imprime PGG
Odetiglucan is a novel β-glucan that is a potent immunostimulant and a Dectin-1 (CLEC7A) agonist. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response [1] .
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Cat. No.: HY-165126
CAS No.: 9050-67-3
Synonyms: SPG
Schizophyllan (SPG) is an orally active extracellular β-glucan produced by the fungus Schizophyllum commune. Schizophyllan improves mitochondrial function and protects against metabolic liver injury by activating the SIRT3 pathway. Schizophyllan inhibits osteoclastogenesis and promotes osteoblast differentiation by suppressing the phosphorylation of JNK/p38, as well as downregulating PGC1β/PPARγ, c-Fos and NFATc1. Recognized via Dectin-1, schizophyllan enables precise delivery of oligonucleotide drugs and antigens to antigen-presenting cells, thus holding great potential in the treatment of inflammatory diseases and vaccine development [1] .
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Cat. No.: HY-N15135
CAS No.: 9040-27-1
Arabinoxylan Medium viscosity is an orally active Dectin-1 splice variant modulator, glucose absorption inhibitor, and chyme viscosity enhancer. Arabinoxylan Medium viscosity inhibits particulate β-glucan-induced Dectin-1A activation and mildly suppresses Dectin-1B activation. In human dendritic cells stimulated with particulate β-glucan, Arabinoxylan Medium viscosity reduces the production of IL-10 and TNF-α, and increases the production of IL-4 and IL-23. Arabinoxylan Medium viscosity also supports antifungal immune responses without activating TLR2, TLR4 or TLR5, and does not induce cytokine production when used to stimulate human dendritic cells alone. Arabinoxylan Medium viscosity increases small intestinal chyme viscosity, gets degraded in the large intestine to produce short-chain fatty acids, reduces glucose absorption and insulin response, and improves glucose homeostasis. Arabinoxylan Medium viscosity supports microbial fermentation and the growth of beneficial microbiota in the gastrointestinal tract, prevents bile acid reabsorption, and delays starch digestion. Arabinoxylan Medium viscosity can be used in research related to type 2 diabetes, impaired glucose tolerance, and metabolic syndrome [1] .
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Cat. No.: HY-159069
CAS No.: 9010-72-4
Purity:  95.02%
Zymosan (ZM), 95% is a yeast cell wall-derived carbohydrate-rich preparation and immunomodulator. Zymosan (ZM), 95% binds to and activates TLR-2, TLR-4, and Dectin-1 receptor to trigger downstream signaling pathways. Zymosan (ZM), 95% upregulates TLR-2, TLR-4, and TNF-α mRNA expression, increases serum TNF-α levels, and stimulates splenocyte number and viability in mice. Zymosan (ZM), 95% attenuates melanoma growth progression, modulates macrophage marker gene expression, and mediates phagocytosis, ROS generation, and cytokine production. Zymosan (ZM), 95% reduces Connexin 43 protein and mRNA levels, inhibits gap junctional intercellular communication, and induces proinflammatory factor production in human corneal cells. Zymosan (ZM), 95% induces peritoneal inflammation in mice, functions as a drug carrier, and supports fibroblast cell attachment in hydrogel formulations. Zymosan (ZM), 95% can be used for the research of melanoma, tumors, fungal keratitis, ocular surface inflammatory disorders, and peritoneal inflammation [1] .
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Cat. No.: HY-P991175
Anti-Dectin-1 Antibody (2M24) is a humanized IgG1 monoclonal antibody that targets Dectin-1. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-159114
Whole Glucan Particles is a Dectin-1a agonist. Whole Glucan Particles activates the innate immune system to improve the function of macrophages, monocytes and other immune cells [1].
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Cat. No.: HY-P700694
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Beta-glucan receptor; DC-associated C-type lectin 1; Dectin-1; Dectin1; CD369; BGR; CLECSF12; Dectin1; CANDF4
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Cat. No.: HY-P704035
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuC-type lectin domain family 7 member A/Dectin-1, Fc; Beta-glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; Dectin1; Dectin-1; Dectin1CANDF4
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Cat. No.: HY-P704036
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuC-type lectin domain family 7 member A/Dectin-1, Fc; Beta-glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; Dectin1; Dectin-1; Dectin1CANDF4
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Cat. No.: HY-RS02800
Research Areas:  

Others

CLEC7A Human Pre-designed siRNA Set A contains three designed siRNAs for CLEC7A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P84769
Synonyms: CLEC7A; BGR; CANDF4; SCARE2; Dectin1; CLECSF12

Host:  

Mouse

Application:  

ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84769A
Synonyms: CLEC7A; BGR; CANDF4; SCARE2; Dectin1; CLECSF12

Host:  

Mouse

Application:  

ICC/IF, FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P75296A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C-type lectin domain family 7 member A; Clecsf12; CD369; Clec7a
Species:  
Source:  
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Cat. No.: HY-P75296
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C-type lectin domain family 7 member A; Clecsf12; CD369; Clec7a
Species:  
Source:  
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