8989 Results for "

Deuterium labeled

" in MedChemExpress (MCE) Product Catalog:

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Aripiprazole-d8-1

11 Publications Verification

Cat. No.: HY-14546S1

CAS No.: 1089115-04-7

Synonyms: OPC-14597-d₈

Aripiprazole (1,1,2,2,3,3,4,4-d₈) is the deuterium labeled Aripiprazole. Aripiprazole (OPC-14597) is a human 5-HT1A receptor partial agonist with a K_i of 4.2 nM .

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Fenbendazole-d3

6 Cited Publications

Cat. No.: HY-B0413S

CAS No.: 1228182-47-5

Fenbendazole-d₃ is a deuterium labeled Fenbendazole. Fenbendazole-d₃ is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .

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Arachidonic acid-d8

5 Cited Publications

Cat. No.: HY-109590S

CAS No.: 69254-37-1

Purity: 99.00%

Synonyms: Immunocytophyt-d₈

Arachidonic acid-d₈ is the deuterium labeled Arachidonic acid. Arachidonic acid is an essential fatty acid and a major constituent of biomembranes .

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L-Leucine-d3

5 Cited Publications

Cat. No.: HY-N0486S9

CAS No.: 87828-86-2

L-Leucine-d₃ is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway .

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Cholic acid-d4

5 Cited Publications

Cat. No.: HY-N0324S

CAS No.: 116380-66-6

Cholic acid-d₄ is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.

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Creatinine-d3

5 Cited Publications

Cat. No.: HY-B0504S

CAS No.: 143827-20-7

Synonyms: NSC13123-d₃

Creatinine-d₃ is a deuterium labeled Creatinine. Creatinine (NSC13123) is an orally active, blood-brain barrier-permeable modulator of GABAA and NMDA receptors, with activities of antioxidation and metabolic regulation. Creatinine is generated via non-enzymatic conversion of creatine and phosphocreatine in muscle. Creatinine serum levels correlate with muscle mass, glomerular filtration rate, and extrarenal clearance, serving as an evaluation biomarker for renal function, muscle mass, and clinical outcomes, and used for perioperative renal risk assessment. In addition, Creatinine can induce specific Cryptococcus species to produce creatinine deiminase and act as their nitrogen source, while it can be secreted via renal tubules. Creatinine is widely used in research related to various diseases such as neurodegenerative diseases, psychiatric disorders, acute kidney injury, chronic kidney disease, and renal failure .

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Quinolinic acid-d3

4 Cited Publications

Cat. No.: HY-100807S

CAS No.: 138946-42-6

Purity: 99.90%

Quinolinic acid-d₃ is the deuterium labeled Quinolinic acid. Quinolinic acid, an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor (NMDA receptor) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS, activates nitric oxide synthase, produces excessive NO, leading to calcium ion influx and neuronal apoptosis.

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Dodecane-d26

3 Cited Publications

Cat. No.: HY-W099602S

CAS No.: 16416-30-1

Dodecane-d₂₆ is the deuterium labeled Dodecane .

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Puromycin-d3

3 Cited Publications

Cat. No.: HY-B1743S

Synonyms: CL13900-d₃

Puromycin-d₃ is the deuterium labeled Puromycin. Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

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Puromycin-d3 dihydrochloride

3 Cited Publications

Cat. No.: HY-B1743AS

Synonyms: CL13900-d3 dihydrochloride

Puromycin-d₃ (dihydrochloride) is the deuterium labeled Puromycin dihydrochloride. Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis .

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Chenodeoxycholic Acid-d4

3 Cited Publications

Cat. No.: HY-76847S

CAS No.: 99102-69-9

Synonyms: CDCA-d₄

Chenodeoxycholic Acid-d₄ is the deuterium labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.

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L-Tryptophan-d5

3 Cited Publications

Cat. No.: HY-N0623S

CAS No.: 62595-11-3

Synonyms: Tryptophan-d₅; Tryptophane-d₅

L-Tryptophan-d₅ is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .

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Myristic acid-d27

3 Cited Publications

Cat. No.: HY-N2041S

CAS No.: 60658-41-5

Myristic acid-d₂₇ is the deuterium labeled Myristic acid. Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.

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Estradiol-d4

3 Cited Publications

Cat. No.: HY-B0141S1

CAS No.: 66789-03-5

Synonyms: β-Estradiol-d₄; 17β-Estradiol-d₄; 17β-Oestradiol-d₄

Estradiol-d₄ is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. Estradiol upregulates IL-6 expression through the estrogen receptor β (ERβ) pathway .

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Lithocholic acid-d4

2 Cited Publications

Cat. No.: HY-B0172S

CAS No.: 83701-16-0

Synonyms: 3α-Hydroxy-5β-cholanic acid-d₄

Lithocholic acid-d₄ is the deuterium labeled Lithocholic acid, which is a toxic secondary bile acid .

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(±)-Equol-d4

2 Cited Publications

Cat. No.: HY-132421S

CAS No.: 1216469-13-4

Purity: 99.79%

(±)-Equol-d₄ is the deuterium labeled (±)-Equol .

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Fexofenadine-d6

2 Cited Publications

Cat. No.: HY-B0801S

CAS No.: 548783-71-7

Synonyms: MDL-16455-d₆; Terfenadine carboxylate-d₆

Fexofenadine-d₆ (MDL-16455-d₆) is deuterium labeled Fexofenadine, which is an antihistamine pharmaceutical agent.

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Vinorelbine-d3 ditartrate

2 Cited Publications

Cat. No.: HY-12053AS

Purity: ≥98.0%

Synonyms: KW-2307-d3 ditartrate; Nor-5'-anhydrovinblastine-d3 ditartrate

Vinorelbine-d₃ (ditartrate) is the deuterium labeled Vinorelbine ditartrate. Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.

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delta-Valerobetaine-d9 chloride

2 Cited Publications

Cat. No.: HY-114202S

CAS No.: 85806-18-4

Purity: ≥98.0%

delta-Valerobetaine-d₉ chloride is the deuterium labeled delta-Valerobetaine (HY-114202) . delta-Valerobetaine is a precursor of trimethylamine N-oxide (TMAO) .

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Creatine-d3

2 Cited Publications

Cat. No.: HY-W010388S1

CAS No.: 143827-19-4

Creatine-d₃ is the deuterium labeled Creatine (HY-W010388) . Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain .

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