55 Results for "

Enterococcus. Faecalis

" in MedChemExpress (MCE) Product Catalog:
Products (55)

55 Results for "Enterococcus. Faecalis" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N0656A
CAS No.: 7562-61-0
(+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer and anti-inflammatory activity. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium .
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Cat. No.: HY-N10264
CAS No.: 269741-97-1
Synonyms: (+)-Avrainvillamide; CJ-17,665
Avrainvillamide ((+)-Avrainvillamide) is a naturally occurring alkaloid with antiproliferative effects, binds to the nuclear chaperone nucleophosmin, a proposed oncogenic protein that is overexpressed in many different human tumors. Avrainvillamide affects cell biology both by directly binding NPM1 and Crm1 as well as by inhibiting the association of these proteins with certain native cellular partners. Avrainvillamide, an antibiotic, inhibits growth of multi-agent resistant Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, with MICs of 12.5, 12.5 and 25 μg/ml, respectively .
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Cat. No.: HY-N13668
CAS No.: 468757-69-9
Rhodomyrtone is an antibiotic that can be found in the leaves of Rhodomyrtus tomentosa. Rhodomyrtone kills Gram-positive bacterial cells without causing bacteriolysis. Rhodomyrtone exhibits activity against a variety of Gram-positive bacteria, including Bacillus cereus, Bacillus subtilis, Enterococcus faecalis, Staphylococcus epidermidis, Streptococcus gordonii, Streptococcus pneumoniae, Streptococcus pyogenes and Streptococcus salivarius. Rhodomyrtone is applicable to studies related to bacterial infections .
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Cat. No.: HY-N2198
CAS No.: 22136-74-9
Podocarpusflavone A is a biflavonoid present in the leaves of Podocarpus henkelii, with anti-tumor, topoisomerase I inhibitory, antibacterial and antifungal activities. Podocarpusflavone A exhibits antibacterial activity against Enterococcus faecalis and Pseudomonas aeruginosa. Podocarpusflavone A shows weak activity against fungal pathogens. Podocarpusflavone A targets topoisomerase I and induces cell cycle arrest and apoptosis in MCF-7 cells. Podocarpusflavone A can be used for studies on cancer, bacterial and fungal infections .
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Cat. No.: HY-N7652
CAS No.: 564-13-6
Terminolic acid is a pentacyclic triterpene glycoside and antibacterial agent. Terminolic acid can be isolated from Combretum racemosum. Terminolic acid inhibits proinflammatory cytokines by binding to the receptor active sites of IL-1β and IL-6. Terminolic acid reduces IL-8. Terminolic acid has antibacterial activity against Staphylococcus aureus, Escherichia coli and Enterococcus faecalis with MICs ranging from 64 to 256 μg/mL. Terminolic acid is used in colon cancer research .
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Cat. No.: HY-W002016
CAS No.: 253-52-1
Phthalazine is a chemical scaffold. Phthalazine derivatives act as VEGFR-2 inhibitors, PARP-1 inhibitors, and anticancer agents. The complex of phthalazine with silver exhibits broad-spectrum antibacterial and antifungal activities against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa PAO1, and Candida albicans. Phthalazine derivatives possess potent vasodilatory activity. Phthalazine can be used in research related to colon adenocarcinoma, breast cancer, hypertension, diabetes, and microbial infections .
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Cat. No.: HY-P5203
CAS No.: 2764845-22-7
Synonyms: EntK1
Target:  

Bacterial

Research Areas:  

Infection

Enterocin K1 (EntK1) is a bacteriocin. Enterocin K1 is a ribosomal synthetic peptide. Enterocin K1 specifically targets Enterococcus faecalis via the Eep protein on the bacterial membrane. Enterocin K1 displays a potent antibacterial activity against VRE. Enterocin K1 can be used for related studies of VRE infections .
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Cat. No.: HY-W587957
CAS No.: 5143-05-5
Target:  

Bacterial Parasite

Research Areas:  

Infection

Gypsogenic acid is a triterpenoid acid that can be isolated from Miconia stenostachya and has antibacterial and trypanoidal activities. The MICs values of Gypsogenic acid for the oral bacterial pathogens Enterococcus faecalis, Streptococcus salivarius, Streptococcus haematococcus, Streptococcus mutans and sobrinus were 50-200 μg/mL. Gypsogenic acid can induce blood cortensite cleavage in isolated mice with IC50 56.6 μM .
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Cat. No.: HY-126461
CAS No.: 521-39-1
Salazinic acid has antibacterial activity against bacteria and fungi. Salazinic acid does not show antibacterial activity against Listeria monocytogenes, Pseudomonas aeruginosa, Yersinia enterocolitica, and Enterococcus faecalis, but it does have antibacterial activity against Pseudomonas aeruginosa and Salmonella typhimurium .
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Cat. No.: HY-143326
CAS No.: 2413865-92-4
Target:  

Bacterial

Research Areas:  

Infection

Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes .
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Cat. No.: HY-W145053
CAS No.: 149358-73-6
Synonyms: Sodium chloro(4-methylbenzenesulfonyl)azanide hydrate
Target:  

Factor Xa Bacterial

Research Areas:  

Infection

ChloraMine-T hydrate (Sodium chloro(4-methylbenzenesulfonyl)azanide (hydrate)) is a common reagent in various synthetic processes. It has been used as a reagent in aminohydroxylation and allylic amination reactions, a nitrogen source in aziridination reactions of alkenes and alkenes, and deprotection of sulfur groups in sulfur-containing compounds. It has been used as a reagent in the synthesis of factor Xa inhibitors. ChloraMine-T hydrate (Sodium chloro(4-methylbenzenesulfonyl)azanide (hydrate)) (0.2% w/v) is also an antimicrobial agent that kills Staphylococcus epidermidis, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Proteus mirabilis, and Enterococcus cloacae.
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Cat. No.: HY-178952
Target:  

Bacterial

Research Areas:  

Infection

Anti-infective agent 12 (Compound A09) is a competitive inhibitor of type I signal peptidease (SPase I), with an IC50 of 4.475 μM and a Kd of 16.3 μM. Anti-infective agent 12 has the ability to disrupt bacterial membranes and remove biofilms. Anti-infective agent 12 exhibits potent bactericidal activity against Gram-positive bacteria, with MIC values of 4, 4, 8, and 8 μg/mL for Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecium, and Streptococcus suis, respectively. Anti-infective agent 12 remains effective against multi-drug resistant strains, but has weaker activity against Gram-negative bacteria (such as Escherichia coli and Salmonella), with MIC values > 64 μg/mL. Anti-infective agent 12 has low hemolytic activity and shows significant efficacy in mouse skin infection models .
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Cat. No.: HY-W923644
CAS No.: 21860-31-1
Synonyms: Aegelinol; (-)-Smyrinol
(-)-Decursinol (Aegelinol; (-)-Smyrinol) is a natural pyranocoumarin compound tant can be isolated from the roots of Apiaceae plants such as Ferulago campestris. (-)-Decursinol inhibits both Gram-positive bacteria (Staphylococcus aureus ATCC 13709, Enterococcus faecalis ATCC 14428) and Gram-negative bacteria (Salmonella typhii ATCC 19430, Enterobacter cloacae ATCC 10699, Enterobacter aerogenes ATCC 13048) with minimum inhibitory concentrations (MIC) ranging from 16 to 64 μg/mL. (-)-Decursinol possesses antioxidant activity. (-)-Decursinol can be used for the study of bacterial infections .
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Cat. No.: HY-N10561
Wychimicin A is a spirotetronate polyketide, can be isolated from the rare actinomycete Actinocrispum wychmicini strain MI503-AF4. Wychimicin A shows strong antibacterial activity against methicillin-resistant Staphylococcus. aureus (IC50=0.125-0.5 μg/mL) and Enterococcus. faecalis/faecium (IC50=0.125-0.25 μg/mL) .
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Cat. No.: HY-N10560
Wychimicin C is a spirotetronate polyketide, can be isolated from the rare actinomycete Actinocrispum wychmicini strain MI503-AF4. Wychimicin C shows strong antibacterial activity against methicillin-resistant Staphylococcus. aureus (IC50=0.125-0.5 μg/mL) and Enterococcus. faecalis/faecium (IC50=0.125-0.25 μg/mL) .
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Cat. No.: HY-E71010
Research Areas:  

Metabolic Disease

NADH Peroxidase, Enterococcus faecalis (EC 1.11.1.1) catalyzes the reversible conversion of NADH and hydrogen peroxide into NAD+ and water.
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Cat. No.: HY-P5554
CAS No.: 163193-68-8
Target:  

Bacterial

Research Areas:  

Infection

cOB1 phermone, a bacterial sex pheromone, effectively inhibits multidrug-resistant Enterococcus faecalis V583 .
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Cat. No.: HY-N14416
CAS No.: 110882-81-0
Parvodicin A is a glycopeptide antibiotic. Parvodicin A has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and Enterococcus faecalis .
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Cat. No.: HY-129166
CAS No.: 2468847-23-4
Target:  

Bacterial

Research Areas:  

Infection

UCM53, a FtsZ inhibitor, is an antibacterial agent. UCM53 can inhibit the growth of clinical isolates of antibiotic-resistant Staphylococcus aureus and Enterococcus faecalis
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Cat. No.: HY-N15040
CAS No.: 110882-87-6
Parvodicin C4 is a glycopeptide antibiotic. Parvodicin C4 has inhibitory effect on Staphylococcus aureus, Staphylococcus furfur, Staphylococcus hemolyticus and Enterococcus faecalis .
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