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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
185 Results for "
Exatecan
" in MedChemExpress (MCE) Product Catalog:
Products (185)
185 Results for "Exatecan" in MCE Product Catalog:
24
24 Publications Verification
Synonyms: DX8951f
Target:
연구분야:
Exatecan mesylate (DX8951f) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL). Exatecan mesylate can be used in cancer research.
24
24 Publications Verification
Synonyms: DX-8951
Target:
연구분야:
Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
14
14 Cited Publications
Synonyms: Exatecan derivative for ADC
Target:
연구분야:
DXd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).
2
2 Cited Publications
Synonyms: MC-Val-Cit-PAB-DX8951
연구분야:
MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. MC-Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker.
1
1 Cited Publications
연구분야:
MC-VA-PAB-Exatecan is a agent-linker conjugate for ADC. MC-VA-PAB-Exatecan contains the ADC linker (peptide MC-VA-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-VA-PAB-Exatecan synthesized ADC shows good antitumor activity .
1
1 Cited Publications
연구분야:
Val-Ala-PABC-Exatecan is a Drug-Linker Conjugates for ADC, consiting of a cleavable Tesirine linker (Val-Ala-PABC) and Exatecan (HY-13631) (topoisomerase I inhibitor). Val-Ala-PABC-Exatecan can be used for ADC molecues synthesis, such as Mal-PEGn-amide-va-Exatecan .
1
1 Cited Publications
연구분야:
GGFG-PAB-Exatecan consists of an ADC toxin Exatecan (HY-13631) and a linker GGFG-PAB, and can be used as a drug-linker conjugate for the synthesis of ADC molecules .
1
1 Cited Publications
연구분야:
Val-Ala-PABC-Exatecan trifluoroacetate is a Drug-Linker Conjugates for ADC, consiting of a cleavable Tesirine linker (Val-Ala-PABC) and Exatecan (topoisomerase I inhibitor, HY-13631). Val-Ala-PABC-Exatecan trifluoroacetate can be used for ADC molecues synthesis, such as Mal-PEGn-amide-va-Exatecan .
Synonyms: DX8951f-d5; Deuterated labeled Exatecan mesylate
Cat. No.: HY-42487
CAS No.: 110351-94-5
Target:
연구분야:
Exatecan Intermediate 1 (compound 6) is an intermediate of Exatecan (HY-13631). Exatecan is a DNA topoisomerase I inhibitor with anticancer effects .
Cat. No.: HY-13631R
CAS No.: 171335-80-1
Synonyms: DX-8951 (Standard)
연구분야:
Exatecan (Standard) is the analytical standard of Exatecan. This product is intended for research and analytical applications. Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
Cat. No.: HY-13631DS
Purity: 98.84%
Synonyms: Exatecan-d5 derivative for ADC
Synonyms: AZ14170132
Target:
연구분야:
(4-NH2)-Exatecan (compound A), a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-160788
CAS No.: 3025107-83-6
연구분야:
DBCO-β-Glu-PEG12-Exatecan (Compound 107) is an inhibitor for topoisomerase I. DBCO-β-Glu-PEG12-Exatecan can be used as a Drug-Linker Conjugate for ADC molecule .
Cat. No.: HY-13631AG
CAS No.: 169869-90-3
Synonyms: DX8951f (GMP)
Cat. No.: HY-171580
연구분야:
Mc-PEG4-Val-Ala-PAB-Exatecan is a Drug-linker conjugate for ADC. Mc-PEG4-Val-Ala-PAB-Exatecan contains the ADC linker (Mc-PEG4-Val-Ala-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631) .
Cat. No.: HY-164792
CAS No.: 2754384-70-6
연구분야:
DBCO-PEG3-VC-Exatecan (compound 25) is a Drug-Linker Conjugate for ADC. DBCO-PEG3-VC-Exatecan contains the ADC linker (DBCO-PEG3-VC) and a DNA topoisomerase I inhibitor Exatecan (HY-13631) .
Cat. No.: HY-164835
CAS No.: 2760408-75-9
Synonyms: VcMMAE-(PAB-GGFG-AMAA)Exatecan; SMP-54418
연구분야:
VcMMAE-Deruxtecan (VcMMAE-(PAB-GGFG-AMAA)Exatecan; SMP-54418) is a drug-linker conjugate for ADC, composed of linker-payload molecule conjugate VcMMAE (HY-15575) and linker-payload molecule conjugate Deruxtecan (PAB-GGFG-AMAA)Exatecan) (HY-13631E). VcMMAE-Deruxtecan can be used in the synthesis of ADCs.
Cat. No.: HY-W021377
CAS No.: 182182-31-6
Target:
연구분야:
Exatecan Intermediate 2 (Compound B) is an intermediate of Exatecan (DX-8951, HY-13631). Exatecan is an anticancer agent belonging to the class of camptothecin analogs. Exatecan interferes with the proliferation and division of tumor cells by interacting with DNA, thereby inhibiting tumor growth. Exatecan is primarily used for research of a variety of cancers including ovarian, lung and breast cancers .
Cat. No.: HY-128995AS
Purity: 95.08%
Synonyms: Glycyl-DX-8951-d5 hydrochloride; Exatecan analog 2-d5 hydrochloride
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
