50 Results for "

Fibrlnogen

" in MedChemExpress (MCE) Product Catalog:
Products (50)

50 Results for "Fibrlnogen" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-125864
CAS No.: 9001-32-5
Fibrinogen (Bovine) is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases .
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2
2 Cited Publications
Cat. No.: HY-125864B
CAS No.: 9001-32-5
Target:  

MMP Cadherin

Murine Fibrinogen is a native fibrinogen derived from mouse plasma. Murine Fibrinogen acts as a cerebrovascular permeability enhancer. Murine Fibrinogen activates matrix metalloproteinase-9 (MMP-9), downregulates the expression of vascular endothelial cadherin (VE-cadherin), and upregulates the expression of plasmalemmal vesicle-associated protein-1 (PV-1). Murine Fibrinogen increases macromolecular leakage from pial veins, thereby disrupting the microvascular integrity of cerebral blood vessels. Murine Fibrinogen can be used in studies related to cerebrovascular dysfunction .
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2
2 Cited Publications
Cat. No.: HY-125864C
CAS No.: 9001-32-5
Research Areas:  

Cardiovascular Disease

Porcine Fibrinogen is a coagulation protein, purified from porcine plasma with no plasminogen contained. Porcine Fibrinogen has excellent biocompatibility and does not induce aggregation of porcine platelets when in contact with porcine hepatocytes, aortic endothelial cells or hepatic sinusoidal endothelial cells. Porcine Fibrinogen is widely used in studies on the pathological mechanisms of cardiovascular diseases such as atherosclerosis and the development of related drugs .
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2
2 Cited Publications
Cat. No.: HY-125864D
CAS No.: 9001-32-5
Research Areas:  

Cardiovascular Disease

Rabbit Fibrinogen is a native fibrinogen from rabbit plasma. Fibrinogen is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases .
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2
2 Cited Publications
Cat. No.: HY-P700990
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FGL2; Fibrinogen-Like Protein 2; Fibrinogen Like 2; T49; Fibroleukin; Fibrinogen-Like 2; PT49
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P1741
CAS No.: 137235-80-4
Research Areas:  

Cardiovascular Disease

Fibrinogen-Binding Peptide is a Fibrinogen-binding peptide. Fibrinogen-Binding Peptide inhibits platelet adhesion to vitronectin and fibrinogen. Fibrinogen-Binding Peptide inhibits platelet aggregation in ADP-stimulated platelet-rich plasma and in thrombin-stimulated washed platelets. Fibrinogen-Binding Peptide can be used for research on thrombosis .
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1
1 Cited Publications
Cat. No.: HY-P1741A
Research Areas:  

Cardiovascular Disease

Fibrinogen-Binding Peptide TFA is a Fibrinogen-binding peptide. Fibrinogen-Binding Peptide TFA inhibits platelet adhesion to vitronectin and fibrinogen. Fibrinogen-Binding Peptide TFA inhibits platelet aggregation in ADP-stimulated platelet-rich plasma and in thrombin-stimulated washed platelets. Fibrinogen-Binding Peptide TFA can be used for research on thrombosis .
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1
1 Cited Publications
Cat. No.: HY-P75772
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGG; Fibrinogen, Gamma Polypeptide; Fibrinogen Gamma Chain; Testicular Tissue Protein Li 70
Species:  
Human
Source:  
P. pastoris
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Cat. No.: HY-125864A
CAS No.: 9001-32-5
Canine Fibrinogen is a natural fibrinogen derived from canine plasma. Canine Fibrinogen specifically binds to the host SpsL, but shows weak binding affinity to fibrinogen from other mammals including humans. Canine Fibrinogen binds to the N2N3 subdomain of SpsL via the "anchor-lock-latch" model, and interacts with multiple sites in its α-chain C domain. The binding of Canine Fibrinogen to SpsL promotes bacterial aggregation, biofilm formation, and enhances bacterial resistance to neutrophil phagocytosis. Canine Fibrinogen can be used in studies related to canine skin infections .
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Cat. No.: HY-P1507
CAS No.: 89105-94-2
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Fibrinogen Binding Inhibitor Peptide is a dodecapeptide (HHLGGAKQAGDV, H12), which is a fibrinogen γ-chain carboxy-terminal sequence (γ400-411). Fibrinogen Binding Inhibitor Peptide is a specific binding site of the ligand for activated glycoprotein (GP) IIb/IIIa.
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Cat. No.: HY-NP167
Fibrinogen from rat plasma can be used to prepare growth factor solutions.
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Cat. No.: HY-P5121A
Target:  

Inhibitory Antibodies

Research Areas:  

Cardiovascular Disease

γ-Fibrinogen377-395 TFA is a fibrinogen-derived inhibitory peptide, as well as fibrinogen epitope. γ-Fibrinogen377-395 TFA blocks microglia activation and inhibits fibrin-Mac-1 interactions in vitro, and suppresses experimental autoimmune encephalomyelitis (EAE) in mice in vivo. γ-Fibrinogen377-395 TFA can be used for research in multiple sclerosis (MS), and other neuroinflammatory diseases associated with blood-brain barrier disruption and microglia activation .
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Cat. No.: HY-P5121B
Target:  

Inhibitory Antibodies

Research Areas:  

Cardiovascular Disease

γ-Fibrinogen 377-395 scrambled TFA is a control peptide that forms a structure similar to that of γ-Fibrinogen 377-395 TFA (HY-P5121A) but possesses a scrambled sequence in the target-binding region.
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Cat. No.: HY-P5121
CAS No.: 957792-67-5
Target:  

Inhibitory Antibodies

Research Areas:  

Cardiovascular Disease

γ-Fibrinogen377-395 is a fibrinogen-derived inhibitory peptide, as well as fibrinogen epitope. γ-Fibrinogen377-395 blocks microglia activation and inhibits fibrin-Mac-1 interactions in vitro, and suppresses experimental autoimmune encephalomyelitis (EAE) in mice in vivo. γ-Fibrinogen377-395 can be used for research in multiple sclerosis (MS), and other neuroinflammatory diseases associated with blood-brain barrier disruption and microglia activation .
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Cat. No.: HY-P5767
CAS No.: 160927-63-9
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Fibrinogen γ-chain (117-133) is a selective intercellular adhesion molecule-1 (ICAM-1) inhibitor (IC50≈20-40 μg/mL). Fibrinogen γ-chain (117-133) blocks fibrinogen-mediated monocyte-endothelial adhesion. Fibrinogen γ-chain (117-133) is promising for research of thrombo-inflammatory diseases (e.g., atherosclerosis, organ transplant rejection) .
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Cat. No.: HY-P3531
CAS No.: 80755-86-8
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Fibrinogen γ-chain (397-411), a esidues 397-411 of the γ chain of fibrinogen, is a site recognizing the platelet receptor, which is distinct from the site(s) involved in polymerization of fibrin monomers .
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Cat. No.: HY-P83924
Synonyms: fibrinogen beta chain

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human

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Cat. No.: HY-P82151
Synonyms: FGG; Fibrinogen gamma chain

Host:  

Rabbit

Application:  

WB, FC

Reactivity:  

Human

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Cat. No.: HY-P85162
Synonyms: FGB; Fibrinogen beta chain

Host:  

Mouse

Application:  

WB, ELISA

Reactivity:  

Human

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Cat. No.: HY-P85163
Synonyms: FGG; Fibrinogen gamma chain

Host:  

Rabbit

Application:  

WB, IHC-P, FC

Reactivity:  

Human

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