38 Results for "

GCSF

" in MedChemExpress (MCE) Product Catalog:
Products (38)

38 Results for "GCSF" in MCE Product Catalog:

  • Recombinant Proteins Recommended:
2
2 Cited Publications
製品番号: HY-P70422
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Granulocyte Colony-Stimulating Factor; G-CSF; Pluripoietin; Filgrastim; Lenograstim; CSF3; C17orf33; GCSF
Species:  
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2
2 Cited Publications
製品番号: HY-P70554
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Granulocyte colony-stimulating factor; Csf3; G-CSF
Species:  
Source:  
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1
1 Cited Publications
製品番号: HY-N0620
CAS 番号: 102841-43-0
Mulberroside C is one of the main bioactive components in white mulberry (Morus alba L.). Mulberroside C exhibits antiplatelet, antiviral and neutrophil-regulating activities, and binds to EV-A71 VP1 with a Kd value of 1.289 nM. Mulberroside C reduces the phosphorylation level of ERK, promotes the phosphorylation of IP3RI at the Ser 1756 site, and decreases calcium influx and calcium mobilization. Mulberroside C inhibits the expression of P-selectin (P-selectin). Mulberroside C upregulates the cyclic nucleotide signaling pathway in human platelets. Mulberroside C binds to IL-23R, upregulates the expression of G-CSF, GM-CSF and RASGRP1, and activates the RAS/ERK signaling pathway. Mulberroside C promotes neutrophil maturation, accelerates the recovery of leukopenia, and enhances the antibacterial activity of neutrophils. Mulberroside C inhibits the replication of hepatitis C virus in replicon cells. Mulberroside C prevents the uncoating and genome release of EV-A71, and inhibits the synthesis of viral proteins and RNA. Mulberroside C can be used in studies related to thrombosis-mediated cardiovascular diseases, chemotherapy- and radiotherapy-induced leukopenia, hepatitis C virus infection, and hand, foot and mouth disease .
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1
1 Cited Publications
製品番号: HY-P73073
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Granulocyte Colony-Stimulating Factor; G-CSF; CSF3; C17orf33
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1 Cited Publications
製品番号: HY-P7093A
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: rRtG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim
Species:  
Rat
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1 Cited Publications
製品番号: HY-P7068
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: rMuG-CSF; CSF-3; MGI-1G; Pluripoietin; Molgramostin; Sargramostim
Species:  
Source:  
CHO
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1
1 Cited Publications
製品番号: HY-P700083AF
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: CSF-3; MGI-1G; GM-CSF beta; pluripoietin
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製品番号: HY-N3018
CAS 番号: 499-40-1
別名: 6-O-α-D-Glucopyranosyl-D-glucose; D-Isomaltose
Isomaltose (6-O-α-D-Glucopyranosyl-D-glucose) is a glucose disaccharide. Isomaltose induces G-CSF secretion via heat-induced oxidative polymerization of glucose groups into high-molecular-weight compounds. Isomaltose modulates cecal bacterial cluster structure in mice. Isomaltose exhibits low glycemic index, slow hydrolysis, and prebiotic properties. Isomaltose reduces in vivo Cryptosporidium parvum colonization in neonatal mice. Isomaltose can be used for the research of Cryptosporidium parvum infection .
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製品番号: HY-P99440
CAS 番号: 2416593-08-1
別名: CSL-324

Target:  

c-Fms JAK STAT

研究分野:  

Inflammation/Immunology

Anumigilimab (CSL-324) is an human IgG4 mAb against human granulocyte colony-stimulating factor (G-CSF) receptor. Anumigilimab can be used for increasing numbers of neutrophils at sites of inflammation .
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製品番号: HY-P99879
CAS 番号: 2200269-79-8
別名: Benegrastim; Bineuta; F 627

Target:  

STAT

研究分野:  

Inflammation/Immunology

Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells .
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製品番号: HY-139410
CAS 番号: 9005-46-3
Sodium caseinates is a kind of sodium salts of major milk proteins, which act as protein-based biopolymers and innate immune system activators. Sodium caseinates induce granulopoiesis, activation and differentiation, promote the production of M-CSF, and increase serum levels of G-CSF and GM-CSF. Sodium caseinates inhibit the proliferation and reduce the viability of leukemia macrophage-like cells, thereby significantly improving the survival rate of mice inoculated with leukemia cells. Sodium caseinates can serve as carriers for probiotics in edible films and exhibit anti-Listeria activity. Sodium caseinates effectively protect vitamin A from degradation, enhance its stability, bioaccessibility and bioavailability, and regulate protein digestibility when complexed with vitamin A. Sodium caseinates can be applied to research related to acute monocytic leukemia and vitamin A deficiency .
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製品番号: HY-W014134
CAS 番号: 74938-88-8
別名: p-Amidinophenylmethylsulfonylfluoride hydrochloride
Target:  

Ser/Thr Protease

研究分野:  

Inflammation/Immunology

p-APMSF (p-Amidinophenylmethylsulfonylfluoride) hydrochloride is a serine protease and trypsin inhibitor with the characteristic of rapid onset of action. p-APMSF hydrochloride reduces the enzymatic hydrolysis of recombinant human G-CSF in rat pulmonary mucosa. Combined intratracheal treatment with p-APMSF hydrochloride and Laureth-9 significantly enhances its absorption efficiency in rat lungs. Following intranasal administration, p-APMSF hydrochloride does not increase the concentration of recombinant human G-CSF in rat plasma, nor does it alter the effect of G-CSF on inducing an increase in total white blood cell count .
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製品番号: HY-176464
CAS 番号: 1206619-37-5
Target:  

TRP Channel

研究分野:  

Inflammation/Immunology

SK2220691 is a potent TRPV4 inhibitor. SK2220691 inhibits pulmonary edema induced by GSK1016790. SK2220691 inhibits HCl-induced increases in key factors such as VEGF, keratinocyte-derived chemokine (KC; CXCL1), and granulocyte colony-stimulating factor (GCSF) .
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製品番号: HY-P99913
CAS 番号: 1384099-30-2

Target:  

c-Fms

研究分野:  

Inflammation/Immunology Cancer

Eflapegrastim is a composite protein consisting of a genetically modified granulocyte-colony stimulating factor (GCSF) molecule linked via a chemical bond to an IgG4 Fc fragment (LAPS-carrier). Eflapegrastim targets to G-CSF receptor (c-Fms). Eflapegrastim stimulates proliferation and differentiation of neutrophil progenitor cells and maintains stable numbers of mature and functional neutrophils. Eflapegrastim also shortens the duration of neutropenia .
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製品番号: HY-178714
Target:  

Interleukin Related

研究分野:  

Inflammation/Immunology

JNJ627 is a small molecule allosteric inhibitor of IL-17A with a KD of 92 nM. JNJ627 effectively inhibits the binding of IL-17A and IL-17RA, with an IC50 value of 16 nM. JNJ627 is capable of inhibiting the secretion of G-CSF (granulocyte colony-stimulating factor) caused by IL-17A stimulation. JNJ627 can be used for the study of autoimmune diseases (such as psoriasis) .
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製品番号: HY-P990963
CAS 番号: 2817686-50-1

Target:  

阻害性抗体

研究分野:  

Inflammation/Immunology Cancer

Albipagrastim alfa is a long-acting granulocyte colony-stimulating factor (G-CSF), which is formed by the fusion of highly active recombinant G-CSF and human serum albumin (HSA). Albipagrastim alfa can significantly inhibit the clearance pathway mediated by the G-CSF receptor. Albipagrastim alfa can be used in tumor-related research .
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製品番号: HY-RS23394
研究分野:  

Others

Csf3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Csf3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-RS03234
研究分野:  

Others

CSF3 Human Pre-designed siRNA Set A contains three designed siRNAs for CSF3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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製品番号: HY-P99458
CAS 番号: 527698-09-5
別名: CG 10639

Target:  

c-Fms

研究分野:  

Cancer

Balugrastim (CG 10639) is a novel long-acting recombinant granulocyte colony-stimulating factor (G-CSF) obtained by means of a genetic fusion between recombinant human serum albumin and granulocyte colony-stimulating factor. Balugrastim can be used for the research of breast cancer .
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製品番号: HY-172257
CAS 番号: 3108252-48-5
研究分野:  

Cancer

HIF-PHD-IN-4 (Compound 13) is an orally active PHD2 inhibitor with an IC50 of 100 nM. HIF-PHD-IN-4 can effectively enhance the mobilization of hematopoietic stem cells induced by G-CSF in mice at a dose of 2 mg/kg. HIF-PHD-IN-4 is suitable for research in the field of tumor therapy .
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