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Results for "

H2O2

" in MedChemExpress (MCE) Product Catalog:

185

Inhibitors & Agonists

19

Fluorescent Dye

4

Biochemical Assay Reagents

12

Peptides

1

Inhibitory Antibodies

55

Natural
Products

7

Isotope-Labeled Compounds

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1776
    Spermidine
    15+ Cited Publications

    Endogenous Metabolite Metabolic Disease
    Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2 .- contents .
    Spermidine
  • HY-P2902
    Glucose oxidase
    5+ Cited Publications

    Endogenous Metabolite Cancer
    Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation .
    Glucose oxidase
  • HY-N0115
    Gastrodin
    15+ Cited Publications

    Gastrodine

    Apoptosis Ferroptosis Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin inhibits ethanol-induced hepatocellular apoptosis. Gastrodin inhibits H2O2-induced ferroptosis through its antioxidative effect. Gastrodin can be used for study of dizziness, epilepsy, stroke and dementia .
    Gastrodin
  • HY-P9930
    Evolocumab
    3 Publications Verification

    AMG 145

    NF-κB Ser/Thr Protease Toll-like Receptor (TLR) Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab is used in the study of hypercholesterolemia and atherosclerotic cardiovascular disease. Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab has antioxidant and cytoprotective activities against H2O2-induced oxidative damage to endothelial cells. Evolocumab may also negatively regulate activation of the TLR-4/NF-κB signaling pathway to prevent inflammation .
    Evolocumab
  • HY-135849
    Catalase, Aspergillus niger
    4 Publications Verification

    Reactive Oxygen Species (ROS) Cancer
    Catalase, Aspergillus niger is a key enzyme in the metabolism of H2O2 and reactive oxygen species (ROS), and its expression and localization is markedly altered in tumors . Free oxygen radical scavenger.
    Catalase, Aspergillus niger
  • HY-N0540
    Cynaroside
    10+ Cited Publications

    Luteolin 7-glucoside; Luteolin 7-O-β-D-glucoside

    Influenza Virus DNA/RNA Synthesis Apoptosis Parasite Bacterial Fungal Infection Cardiovascular Disease Cancer
    Cynaroside (Luteolin 7-glucoside) is a flavonoid compound that exhibits anti-oxidative capabilities. Cynaroside is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 32 nM. Cynaroside also is a promising inhibitor for H2O2-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases. Cynaroside also has antibacterial, antifungal and anticancer activities, antioxidant and anti-inflammatory activities .
    Cynaroside
  • HY-B1776A
    Spermidine hydrochloride
    15+ Cited Publications

    Endogenous Metabolite Metabolic Disease
    Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2 .- contents .
    Spermidine hydrochloride
  • HY-N2410

    N-feruloyltyramine; Moupinamide

    Reactive Oxygen Species (ROS) Apoptosis Inflammation/Immunology
    N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid, is a potent antioxidant. N-trans-Feruloyltyramine improves H2O2-induced intracellular ROS generation and decreases apoptosis. N-trans-Feruloyltyramine has the potential for oxidative stress-related neurodegenerative conditions and cancer research .
    N-trans-Feruloyltyramine
  • HY-N1318
    Salvigenin
    5+ Cited Publications

    Psathyrotin

    Autophagy Apoptosis ROS Kinase Neurological Disease Inflammation/Immunology Cancer
    Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties. Salvigenin inhibits H2O2-induced cell apoptosis .
    Salvigenin
  • HY-P2861

    SAO

    Endogenous Metabolite Others
    Sarcosine oxidase, Bacillus (SAO) can catalyze the oxidative demethylation of sarcosine to generate glycine, H2O2, 5,10-CH2-tetrahydrofolate, which are often used in biochemical reactions .
    Sarcosine oxidase, Bacillus
  • HY-N0615
    Notoginsenoside R1
    2 Publications Verification

    Sanchinoside R1; Sanqi glucoside R1

    Amyloid-β Apoptosis Others
    Notoginsenoside R1 (Sanchinoside R1), a saponin, is isolated from P. notoginseng. Notoginsenoside R1 exhibits anti-oxidation, anti-inflammatory, anti-angiogenic, and anti-apoptosis activities. Notoginsenoside R1 provides cardioprotection against ischemia/reperfusion (I/R) injury. Notoginsenoside R1 also provides neuroprotection in H2O2-induced oxidative damage in PC12 cells .
    Notoginsenoside R1
  • HY-D1458

    Fluorescent Dye Cardiovascular Disease Neurological Disease Cancer
    Peroxyfluor 1 is a cell-permeable probe for H2O2. Peroxyfluor 1 represents a first-generation, green-fluorescent probe .
    Peroxyfluor 1
  • HY-103469
    Peroxy Orange 1
    3 Publications Verification

    PO1

    Fluorescent Dye Others
    Peroxy Orange 1 (PO1) is a new H2O2 specific probe that can bind to green fluorescent highly reactive oxygen species (hROS) probe APF. Peroxy Orange 1 is also a living cell dye .
    Peroxy Orange 1
  • HY-109804
    CORM-401
    10+ Cited Publications

    Reactive Oxygen Species (ROS) Inflammation/Immunology
    CORM-401 is an oxidant-sensitive CO-releasing molecule. CORM-401 induces NO increase in the regulation of endothelial calcium signalling. CORM-401 reduces TNF-α/CHX and H2O2-induced ROS production. CORM-401 uncouples mitochondrial respiration and inhibits glycolysis .
    CORM-401
  • HY-109110

    GC-4419; M-40419

    Reactive Oxygen Species (ROS) Inflammation/Immunology Cancer
    Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2 *- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer .
    Avasopasem manganese
  • HY-15914

    DCHBS

    Fluorescent Dye Others
    DHBS (3, 5-dichloro-2-hydroxybenzenesulfonate) is used in conjunction with 4-aminoantipyrine (4-AAP) (HY-W100990) and hydrogen peroxide (H2O2) for chromogenic quantitation of peroxidase in coupled enzymatic reactions. Component of Trinder reagent for use with peroxidase to measure generation of hydrogen peroxide in automated systems .
    DHBS
  • HY-133114

    EZM-K

    Keap1-Nrf2 Autophagy Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
    Ezetimibe ketone is an oral Nrf2 activator and ROS inhibitor. Ezetimibe ketone attenuates H2O2-induced reactive oxygen species production and reduces H2O2-induced apoptosis in renal tubular epithelial cells. Ezetimibe ketone suppresses renal tubular injury and inflammation .
    Ezetimibe ketone
  • HY-B1776R

    Reference Standards Endogenous Metabolite Metabolic Disease
    Spermidine (Standard) is the analytical standard of Spermidine. This product is intended for research and analytical applications. Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents .
    Spermidine (Standard)
  • HY-101859
    NucPE1
    5 Publications Verification

    Nuc-H2O2 Probe

    Reactive Oxygen Species (ROS) Others
    NucPE1 (Nuc-H2O2 Probe) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties.
    NucPE1
  • HY-125859B

    Bacterial Infection
    Lactoperoxidase, bovine milk is an antimicrobial protein that belongs to the mammalian heme peroxidase family. Lactoperoxidase, bovine milk uses H2O2 to catalyze the oxidation of its preferred halide substrates including I , Br , F , or the pseudohalide SCN .
    Lactoperoxidase, bovine milk
  • HY-D1157
    HKPerox-2
    5 Publications Verification

    Fluorescent Dye Reactive Oxygen Species (ROS) Others
    HKPerox-2 is a highly sensitive green fluorescent probe for the specific detection of H2O2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
    HKPerox-2
  • HY-120972

    Fluorescent Dye Others
    Pentafluorobenzenesulfonyl fluorescein is a H2O2-selective sensor that can be used to detect H2O2 levels in cells. Pentafluorobenzenesulfonyl fluorescein is generally non-fluorescent, but emits fluorescence when its sulfonyl bond undergoes perhydrolysis by H2O2 . Pentafluorobenzenesulfonyl fluorescein undergoes slight cleavage of its sulfonate ester bond by [Cu (phen)2] 2+, and can detect hydrogen peroxide around the ablation sites of fin tissues and keratinocytes in zebrafish larvae .
    Pentafluorobenzenesulfonyl fluorescein
  • HY-15933
    TOPS
    1 Publications Verification

    Biochemical Assay Reagents Others Metabolic Disease
    TOPS is a chromogenic substrate. TOPS undergoes an oxidative coupling reaction with 4-aminoantipyrine in the presence of H2O2 and nanocrystalline cobalt selenide. TOPS is used in studies related to uric acid detection .
    TOPS
  • HY-N2565
    Rosamultin
    1 Publications Verification

    HIV Protease Apoptosis Infection
    Rosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina?L. Rosamultin has inhibitory effects against HIV-1 protease . Rosamultin has the potential for treating H2O2-induced oxidative stress injury through its antioxidant and antiapoptosis effects .
    Rosamultin
  • HY-108351

    Necroptosis Cardiovascular Disease
    IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death .
    IM-54
  • HY-119171

    KMO Neurological Disease Inflammation/Immunology
    GSK 366 is a type II kynurenine-3-monooxygenase (KMO) inhibitor with IC50 values of 2.3 nM and 0.7 nM for human KMO and P. fluorescens-KMO (Pf-KMO). GSK 366 binds to KMO’s substrate site, prevents productive NADPH association, substrate binding, and FAD hydroperoxy species formation. GSK 366 does not stimulate hydrogen peroxide (H2O2) production and reduces H2O2 levels. GSK 366 can be used for the researches of inflammation and neurological disease, such as acute pancreatitis multiple organ dysfunction syndrome and Alzheimer’s disease .
    GSK 366
  • HY-N0501
    11-oxo-mogroside V
    1 Publications Verification

    Reactive Oxygen Species (ROS) Metabolic Disease
    11-oxo-mogroside V is a natural sweetener that exhibits strong antioxidant activity. It exhibits significant inhibitory effects on reactive oxygen species (O2 -, H2O2 and *OH) with EC50 of 4.79, 16.52, and 146.17 μg/mL, respectively.
    11-oxo-mogroside V
  • HY-B1776AS1
    Spermidine-13C4 hydrochloride
    1 Publications Verification

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Spermidine- 13C4 (hydrochloride) is the 13C-labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents .
    Spermidine-13C4 hydrochloride
  • HY-N7880

    Reactive Oxygen Species (ROS) Cancer
    Salvianolic acid Y is a phenolic acid with the same planar structure as Salvianolic acid B. Salvianolic acid Y rescues cell injury by H2O2 .
    Salvianolic acid Y
  • HY-164926

    PARP Neurological Disease
    PARP1-IN-33 (Example 6) is a PARP1 inhibitor (IC50: 0.41 nM). PARP1-IN-33 has retinal cytoprotective effect, with an EC50 of 0.02 nM (inhibition on MTS activity of H2O2 induced human retinal pigment epithelial cell) .
    PARP1-IN-33
  • HY-115386
    MitoTEMPOL
    3 Publications Verification

    Reactive Oxygen Species (ROS) Cancer
    MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2 -to H2O2 .
    MitoTEMPOL
  • HY-N5021

    AHSYB

    Others Neurological Disease
    Anhydrosafflor yellow B (AHSYB) is a quinochalcone C-glycoside isolated from Carthamus tinctorius. Anhydrosafflor yellow B inhibits ADP-induced platelet aggregation, exhibits significant anti-oxidative effects in vitro, and possesses certain activity against H2O2-induced cytotoxicity in cultured PC12 cells and primary neuronal cells .
    Anhydrosafflor yellow B
  • HY-B1776S
    Spermidine-d6
    1 Publications Verification

    Endogenous Metabolite Metabolic Disease
    Spermidine-d6 is the deuterium labeled Spermidine . Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents .
    Spermidine-d6
  • HY-125919

    Reactive Oxygen Species (ROS) Bacterial Endogenous Metabolite Infection Inflammation/Immunology
    Vulpinic acid, a lichen metabolite, decreases H2O2-induced ROS production, oxidative stress and oxidative stress-related damages in human umbilical vein endothelial cells (HUVEC). Vulpinic acid is active against staphylococci, enterococci, and anaerobic bacteria.Vulpinic acid has the potential for atherosclerosis research .
    Vulpinic acid
  • HY-N2627

    Others Cancer
    Isorhamnetin 3-O-robinobioside is a flavonoid compound. Isorhamnetin shows a protective effect against lipid peroxidation induced by H2O2. Isorhamnetin 3-O-robinobioside also inhibits the genotoxicity induced by hydroxyl radicals .
    Isorhamnetin 3-O-robinobioside
  • HY-B1776AS

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Spermidine-d8 (hydrochloride)e is the deuterium labeled Spermidine trihydrochloride. Spermidine hydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine hydrochloride significantly decreases the H2O2 and O2.- contents .
    Spermidine-d8 hydrochloride
  • HY-D1693

    Fluorescent Dye Inflammation/Immunology Cancer
    FBBBE is used to detect the production of H2O2 by cells. FBBBE can be triggered by intracellular H2O2 and converted to fluorescein, resulting in an increase in intracellular fluorescence (Ex=4480 nm, Em=512 nm) .
    FBBBE
  • HY-N7697E

    Others Others
    Chitotriose trihydrochloride is an orally active chitooligosaccharide with antioxidant activities. Chitotriose trihydrochloride inhibits hydroxylation of benzoate to salicylate by H2O2 in the presence of Cu 2+ (IC50 value of 80 μM) .
    Chitotriose trihydrochloride
  • HY-N3287

    Bacterial Fungal Reactive Oxygen Species (ROS) Infection
    Methyl 3-hydroxy-4,5-dimethoxybenzoate is a gallic acid derivant that can be isolated from myricaria Laxiflora. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows obvious antimicrobial activities. Methyl 3-hydroxy-4,5-dimethoxybenzoate shows fairly active for oxidation resistance in the presence of H2O2 .
    Methyl 3-hydroxy-4,5-dimethoxybenzoate
  • HY-130022
    HKPerox-1
    2 Publications Verification

    Fluorescent Dye Others
    HKPerox-1 is a highly sensitive green fluorescent probe for the specific detection of H2O2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
    HKPerox-1
  • HY-101193R

    Zn(II)-protoporphyrin IX (Standard); ZnPP (Standard); Zinc Protoporphyrin-9 (Standard)

    Reference Standards Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis Cardiovascular Disease Metabolic Disease Cancer
    Zinc Protoporphyrin (Standard) is the analytical standard of Zinc Protoporphyrin. This product is intended for research and analytical applications. Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H2O2 . Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration . Zinc Protoporphyrin has anti-cancer activity .
    Zinc Protoporphyrin (Standard)
  • HY-P10400

    Phytohormone Inflammation/Immunology
    AtPep1 is a plant elicitor peptide. AtPep1 activates transcription of the defensive gene defensin (PDF1.2) and activates the synthesis of H2O2, which are components of the innate immune response against pathogens. AtPep1 can be isolated from extracts of Arabidopsis leaves .
    AtPep1
  • HY-D1065

    Fluorescent Dye Inflammation/Immunology
    NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. NIR-H2O2 has both absorption and emission in the NIR region. NIR-H2O2 responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. NIR-H2O2 is capable of imaging endogenously produced H2O2 in living cells and mice .
    NIR-H2O2
  • HY-W110905

    Environmental Pollutants Fluorescent Dye Others
    Naphthol green B is an iron-complex dye. Naphthol green B can be used in wool dyeing, silk dyeing and polyamide dyeing. Naphthol green B can be used to fabricate electrochemical sensor for the detection of H2O2 .
    Naphthol green B
  • HY-N2442

    Reactive Oxygen Species (ROS) Metabolic Disease
    Methylophiopogonone B, a homoisoflavonoidal compound that could be isolated from Ophiopogonis Tiber, could scavenge •OH and H2O2 in vitro to a certain extent .
    Methylophiopogonone B
  • HY-D3000

    Fluorescent Dye Metabolic Disease
    NIR-RED ROS-H2O2 Probe is a near-infrared fluorescent probe used for detecting hydrogen peroxide (H₂O₂) and featuring dual-modal fluorescence/photoacoustic imaging capabilities. NIR-RED ROS-H2O2 Probe successfully detects the upregulated fluorescence signal of H₂O₂ in HepG2 cells and a mouse liver injury model. NIR-RED ROS-H2O2 Probe can be used as a biomarker detection tool for drug-induced liver injury (DILI) .
    NIR-RED ROS-H2O2 Probe
  • HY-N15756

    Reactive Oxygen Species (ROS) Neurological Disease Inflammation/Immunology
    N-Demethylsinomenine is a morphinane alkaloid that can be isolated from Sinomenium acutum. N-Demethylsinomenine has a protective effect against H2O2-induced cell injury. N-Demethylsinomenine can be used in the research of diseases such as Alzheimer's disease .
    N-Demethylsinomenine
  • HY-W927359

    Fluorescent Dye Others
    Fluorescein hydrazide (3,6-Dihydroxyxanthane) is a fluorescein dye that can be used for the fluorophotometric determination of hydrogen peroxide (H2O2) and other reactive oxygen species (ROS) .
    Fluorescein hydrazide (3,6-Dihydroxyxanthane)
  • HY-132927B

    Reactive Oxygen Species (ROS) Inflammation/Immunology
    Salpyran dihydrochloride is a Cu(II) selective chelator with therapeutic potential. Salpyran dihydrochloride prevents the formation of reactive oxygen species from the binary Cu(II)/H2O2 system .
    Salpyran dihydrochloride
  • HY-D2965

    SPG1

    Fluorescent Dye Others
    SNAP-Peroxy-Green-1 (SPG1) a SNAP tag fluorescent probe. SNAP-Peroxy-Green-1 can be used for detecting H2O2 in the extracellular space or on the surface of the cell membrane .
    SNAP-Peroxy-Green-1

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