13 Results for "

Hyperproliferative.

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "Hyperproliferative." in MCE Product Catalog:

Cat. No.: HY-139601
CAS No.: 1966933-85-6
Purity:  99.59%
Target:  

Histone Demethylase

Research Areas:  

Cancer

KDM2B-IN-4 (Compound 182b) is a histone demethylase KDM2B inhibitor with an IC50 of 1.12 nM. KDM2B-IN-4 can be used for the research of hyperproliferative diseases such as cancers .
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Cat. No.: HY-139560
CAS No.: 1965248-33-2
Purity:  99.19%
Target:  

Histone Demethylase

Research Areas:  

Inflammation/Immunology Cancer

KDM2B-IN-1 (example 32) is a histone demethylase (kdm2b) inhibitor with an IC50 of 0.016 nM. KDM2B-IN-1 can be used for hyperproliferative diseases research .
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Cat. No.: HY-16461
CAS No.: 137038-57-4
Synonyms: (-)-Solenopsin A
Solenopsin ((-)-Solenopsin A) is an ATP-competitive and selective Akt-1 inhibitor with an IC50 of 5-10 μM, and also acts as an RSK1 inhibitor. Solenopsin inhibits the activities of PDK1 in lipid rafts, downregulates PI3K, blocks PI3K-dependent generation of 3-phosphoinositides, and suppresses the phosphorylation of FOXO1a. Solenopsin induces Mitophagy and ROS production, reduces mitochondrial oxygen consumption, and exhibits antiproliferative and antiangiogenic activities. Solenopsin can be used in research related to hyperproliferative skin diseases and malignant diseases .
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Cat. No.: HY-W000773
CAS No.: 937046-98-5
Target:  

Drug Derivative

Research Areas:  

Cardiovascular Disease

7-Bromopyrrolotriazin-4-amine (Compound 3-7) is a pyrrolotriazine derivative. 7-Bromopyrrolotriazin-4-amine is applicable to the study of hyperproliferative diseases and angiogenesis-related diseases .
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Cat. No.: HY-142677
CAS No.: 2742654-38-0
Target:  

PI3K

Research Areas:  

Inflammation/Immunology Cancer

PI3K-IN-27 is a potent inhibitor of PI3K. PI3K belongs to a large family of lipid signaling kinase that plays key role in cellular process including cell growth, differentiation, migration and apoptosis. PI3K-IN-27 has the potential for the research of hyper-proliferative diseases like cancer and inflammation, or immune and autoimmune diseases (extracted from patent WO2021233227A1, compound 1) .
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Cat. No.: HY-U00366
CAS No.: 1149727-61-6
Target:  

LPL Receptor

Research Areas:  

Inflammation/Immunology

S1PR-MO-1 is the modulator of sphingosine-1-phosphate receptor, used for research of hyperproliferative, inflammatory diseases.
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Cat. No.: HY-121638B
CAS No.: 861123-84-4
(E/Z)-CU-3 is a MCL-1 modulator. (E/Z)-CU-3 can be used to study hyperproliferative diseases, angiogenic diseases, cell cycle regulation diseases, autophagy regulation diseases, inflammatory diseases and/or infectious diseases .
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Cat. No.: HY-401475
CAS No.: 262433-52-3
Target:  

PKC

Protein kinase inhibitor 9 (Compound example 175) is an inhibitor of serine/threonine and tyrosine kinase activity. Protein kinase inhibitor 9 can be used for the research of cancer, hyper proliferative disorders, rheumatoid arthritis, disorders of the immune system, transplant rejections and imflammatory disorders .
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Cat. No.: HY-175734
CAS No.: 2019131-11-2
Target:  

PI3K

Research Areas:  

Inflammation/Immunology

PI3Kδ-IN-26 (Compound 58) is a selective and orally active PI3Kδ inhibitor with an IC50 of 14  nM. PI3Kδ-IN-26 significantly attenuates the inflammatory responses in house dust mite (HDM) induced chronic asthma mouse models. PI3Kδ-IN-26 can be used for inflammatory, autoimmune and hyperproliferative diseases research .
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Cat. No.: HY-155243
CAS No.: 857758-13-5
Target:  

DNA/RNA Synthesis

Research Areas:  

Inflammation/Immunology

12R-LOX-IN-1 (Compound 4a) is a 12R-LOX inhibitor (IC50: 28.25 μM). 12R-LOX-IN-1 inhibits the hyper-proliferative state and colony forming potential of Imiquimod (HY-B0180)-induced psoriatic keratinocytes. 12R-LOX-IN-1 inhibits reactive oxygen species, Ki67, IL-17A, TNF-α and IL-6 production. 12R-LOX-IN-1 can be used for antipsoriatic research .
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Cat. No.: HY-177274
CAS No.: 182878-97-3
Target:  

Mitosis

Research Areas:  

Inflammation/Immunology

Antimitotic agent-2 (Compound 1) is an antimitotic agent. Antimitotic agent-2 inhibits the proliferation of human epidermal cells. Antimitotic agent-2 can be used in hyperproliferative skin disorders .
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Cat. No.: HY-155865
CAS No.: 2902671-74-1
Target:  

Kinesin

Research Areas:  

Cancer

CCT368772 (compound 35) is a selective kinesin HSET inhibitor (HSET ADP-Glo IC50 = 0.019 μM). CCT368772 exhibits selectivity over Eg5 (Eg5 ADP-Glo IC50 >200 μM) . CCT368772 (compound 152) can be used for the study of hyperproliferative diseases and disorders such as cancer .
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Cat. No.: HY-164534
CAS No.: 1648864-21-4
SIK2/3-IN-2 (compound 12, compound I-200) is a potent SIK2/3 inhibitor (SIK2 IC50 = 65 nM, SIK3 IC50 = 14 nM). SIK2/3-IN-2 is also a p21-activated protein kinase (PAK) 1 inhibitor with a Ki of 20.7 nM. SIK2/3-IN-2 can be used for hyperproliferative diseases and cancer research, such as Paclitaxel (HY-B0015)-resistant ovarian cancer .
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