126 Results for "

IL13

" in MedChemExpress (MCE) Product Catalog:
Products (126)

126 Results for "IL13" in MCE Product Catalog:

28
28 Publications Verification
製品番号: HY-P70568
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Interleukin-13; IL-13
Species:  
Source:  
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26
26 Cited Publications
製品番号: HY-P70460
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Interleukin-13; IL-13; T-Cell Activation Protein P600; IL13; IL-13
Species:  
Source:  
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17
17 Cited Publications
製品番号: HY-P72795
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Interleukin-13; IL-13
Species:  
Source:  
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14
14 Cited Publications
製品番号: HY-B0539
CAS 番号: 100643-71-8
別名: Sch34117
Desloratadine (Sch34117) is an orally active and selective H1 receptor antagonist (Ki=0.9 nM) with anti-inflammatory and anti-allergic activities. Desloratadine inhibits the release of histamine and LTC4 from human basophils and targets the regulatory signals of IL-4 and IL-13 production in basophils. Desloratadine significantly alleviates SAR symptoms in patients with concurrent asthma and can be used in the study of seasonal allergic rhinitis and chronic idiopathic urticaria .
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9
9 Cited Publications
製品番号: HY-P7033
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: rHuIL-13; NC30
Species:  
Source:  
CHO
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8
8 Cited Publications
製品番号: HY-P9926
CAS 番号: 1190264-60-8
別名: REGN-668; SAR-231893

Target:  

Interleukin Related

研究分野:  

Inflammation/Immunology Cancer

Dupilumab (REGN-668) is a fully human mAb to IL-4 receptor α (IL-4Rα) that inhibits both IL-4 and IL-13 signaling, markedly improved moderate-to-severe atopic dermatitis .
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3
3 Cited Publications
製品番号: HY-P7076A
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: rMuIL-13, His; P600
Species:  
Source:  
CHO
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2
2 Cited Publications
製品番号: HY-P99053
CAS 番号: 1044515-88-9
別名: CAT354
Tralokinumab (CAT354) is a humanized IgG4 monoclonal antibody that specifically binds to and neutralizes IL-13. Tralokinumab can be used in the research of diseases such as asthma, atopic dermatitis, and pulmonary fibrosis .
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2
2 Cited Publications
製品番号: HY-P1848
CAS 番号: 395069-86-0
Target:  

Interleukin Related

研究分野:  

Cancer

Pep-1 (uncapped) is a specific ligand of IL-13Ra2. Pep-1 (uncapped) exerts cell penetrating activity through receptor-mediated endocytosis, can cross the blood-tumor barrier (BTB) and target glioma cells. Pep-1 (uncapped) can enhance the uptake of nanoparticles by tumor cells and enhance the cell penetration ability of nanoparticles, and can be used to develop targeted drug delivery systems for glioma .
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1
1 Cited Publications
製品番号: HY-P99025
CAS 番号: 953400-68-5
別名: TNX-650; MILR1444A; RG3637

Target:  

Interleukin Related

研究分野:  

Inflammation/Immunology

Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 (IL-13) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases .
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1
1 Cited Publications
製品番号: HY-P99496
CAS 番号: 2151032-62-9
別名: RPC 4046; ABT 308; CC-93538

Target:  

Interleukin Related

研究分野:  

Inflammation/Immunology

Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the IL-13 molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC50s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases (e.g., asthma and eosinophilic esophagitis) .
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1
1 Cited Publications
製品番号: HY-P990121

Target:  

Interleukin Related

研究分野:  

Inflammation/Immunology Cancer

Anti-Mouse IL-4 Antibody (11B11) is an anti-mouse IL-4 IgG1 monoclonal antibody. Anti-Mouse IL-4 Antibody (11B11) can inhibit Th2 cell differentiation by blocking the IL-4 signaling pathway. Anti-Mouse IL-4 Antibody (11B11) can significantly reduce fibrosis combined with anti-IL13 mAb. Anti-Mouse IL-4 Antibody (11B11) can be used for researches on cancer and inflammation conditions such as colorectal cancer and prostatitis .
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1
1 Cited Publications
製品番号: HY-P7099
純度:  ≥ 98%, as determined by reducing SDS-PAGE.;≥ 98%, as determined by HPLC.
別名: Interleukin-13; IL-13; T-Cell Activation Protein P600; IL13
Species:  
Rat
Source:  
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1
1 Cited Publications
製品番号: HY-P72595
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Interleukin-13; IL-13; T-Cell Activation Protein P600; IL13
Species:  
Source:  
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1
1 Cited Publications
製品番号: HY-P70779
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: Interleukin-13; IL-13;
Species:  
Source:  
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製品番号: HY-145551
CAS 番号: 2169273-59-8
純度:  98.03%
Target:  

JAK Interleukin Related

研究分野:  

Inflammation/Immunology

Atinvicitinib is an orally active and selective JAK1 inhibitor. Atinvicitinib blocks signaling of JAK1-dependent pruritogenic and pro-inflammatory cytokines, including those in the IL-31, IL-4, and IL-13 pathways. Atinvicitinib can be used for the researches of pruritus associated with allergic dermatitis and canine atopic dermatitis .
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製品番号: HY-P990093
CAS 番号: 2734715-10-5
別名: CM310

研究分野:  

Inflammation/Immunology

Stapokibart (CM310) is a humanized monoclonal antibody targeting IL-4Rα (KD values of 0.25 nM, 1.50 nM, and 2.75 nM for human, cynomolgus monkey, and rat IL-4Rα, respectively). Stapokibart effectively blocks the interaction of cytokines IL-4 and IL-13 with their co-receptor subunit IL-4Rα. Stapokibart reduces IL-4 and IL-13 mRNA, inhibits CD23 upregulation, and inhibits IL-4 and IL-13-induced STAT6 activation. Stapokibart improves inflammation (airway inflammation, rhinitis, dermatitis) .
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製品番号: HY-P991162
CAS 番号: 2981469-90-1
別名: PF-07275315

Target:  

Interleukin Related

研究分野:  

Inflammation/Immunology

Tilrekimig (PF-07275315) is a monoclonal antibody targeting human interleukin-4 (IL-4), interleukin-13 (IL-13) and thymic stromal lymphopoietin (TSLP). Tilrekimig can be used in the research of allergic and inflammatory diseases, such as asthma and atopic dermatitis .
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製品番号: HY-P990748
CAS 番号: 2770858-49-4
別名: SAR443765

Target:  

Interleukin Related

研究分野:  

Inflammation/Immunology

Lunsekimig (SAR443765) is a TSLP/IL-13 inhibitor. Lunsekimig blocks the functional activities of TSLP and IL-13, suppresses type 2 inflammation and improves pulmonary function. Lunsekimig is applicable to research related to asthma .
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製品番号: HY-P2797A
CAS 番号: 9001-06-3
別名: AMCase, Streptomyces griseus
研究分野:  

Others

Chitinase, Streptomyces griseus is a chitinase from Streptomyces griseus. Chitinase is a chitin-targeting enzyme with chitin hydrolysis activity. Chitinase inhibits chitin-induced innate type 2 inflammation in the lung. Chitinase augments chitin-free, allergen-induced Th2 inflammation. Chitinase mediates effector functions of IL-13 .
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