57 Results for "

IL22

" in MedChemExpress (MCE) Product Catalog:
Products (57)

57 Results for "IL22" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P7039
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuIL-22; Cytokine Zcyto 18; IL-TIF
Species:  
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3
3 Cited Publications
Cat. No.: HY-P72793
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-22; IL-22; IL-TIF; IL-TIF alpha; IL-22a
Species:  
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P99919
CAS No.: 2247840-74-8

Target:  

Interleukin Related

Research Areas:  

Infection

Efmarodocokin alfa is a fusion protein of human IL-22 and the IgG4 crystallizable fragment. Efmarodocokin alfa activates IL-22 signaling. Efmarodocokin alfa can be used for the research of severe COVID-19 pneumonia .
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1
1 Cited Publications
Cat. No.: HY-P7079
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuIL-22; Cytokine Zcyto 18; IL-TIF
Species:  
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1
1 Cited Publications
Cat. No.: HY-P77969
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL-22R-alpha-1; IL-22RA1; CRF2-9; IL22R; IL22R1; IL-TIF-R1; zcytoR11
Species:  
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Cat. No.: HY-P990735
CAS No.: 2765066-99-5
Synonyms: UCB-1381

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Donzakimig is a trispecific anti-IL-13/IL-22/HSA antibody. Donzakimig adopts a Fab-scFv-scFv structural format (without an Fc region), in which the Fab domain is linked to the scFv domains via a S (G4S)2 linker. Donzakimig binds to and inhibits the activities of IL-13 and IL-22, thereby blocking the signal transduction of these two cytokines. Donzakimig can extend its serum half-life by binding to human serum albumin, enhancing its in vivo stability and achieving long-acting efficacy. Donzakimig can be used in research on moderate-to-severe atopic dermatitis, moderate-to-severe asthma (especially eosinophilic type), psoriasis, inflammatory bowel disease, and other conditions .
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Cat. No.: HY-P99917
CAS No.: 2200269-84-5
Synonyms: F-652; rhIL-22 dimer

Target:  

STAT

Research Areas:  

Infection Inflammation/Immunology

Eflepedocokin alfa is a recombinant fusion protein. Eflepedocokin alfa consists of human IL-22 fused to human IgG2-Fc domain. Eflepedocokin alfa leads to the activation of IL-22/IL-22R-mediated signal transduction pathways as well as STAT3. Eflepedocokin alfa plays a role in immune response and bacterial infection, enhancing intestinal barrier function, intestinal immunity, and tissue repair .
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Cat. No.: HY-P99244
CAS No.: 1007106-86-6
Synonyms: ILV 094
Fezakinumab (ILV 094) is an anti-IL-22 monoclonal antibody. Fezakinumab inhibits IL-22 signal transduction, and regulates the JAK1/STAT3 pathway as well as apoptotic proteins. Fezakinumab alleviates airway remodeling, alveolar enlargement and inflammatory cell infiltration in lung tissues. Fezakinumab reduces the levels of neutrophils, lymphocytes, eosinophils and macrophages in lung tissues. Fezakinumab can be used in the research of chronic obstructive pulmonary disease and skin diseases .
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Cat. No.: HY-P990016
CAS No.: 2639874-57-8
Synonyms: ARGX-112; LEO-138559; LP-0145

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Temtokibart (ARGX-112) is a monoclonal antibody and also an IL-22RA1 inhibitor. Temtokibart inhibits the signal transduction of IL-22, IL-20 and IL-24. Temtokibart reduces the expression levels of inflammatory proteins, chemokines, immune cell migration and markers of activated immune pathways. Temtokibart improves the expression of genes related to immunity and epidermal barrier function. Temtokibart is applicable to research on moderate-to-severe atopic dermatitis .
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Cat. No.: HY-174620
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL22 mRNA encodes the human interleukin 22 (IL22) protein, a member of the IL10 family of cytokines that mediate cellular inflammatory responses. IL22 functions in antimicrobial defense at mucosal surfaces and in tissue repair. It also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases.
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Cat. No.: HY-RS16854
Research Areas:  

Others

Il22 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il22 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS06736
Research Areas:  

Others

IL22 Human Pre-designed siRNA Set A contains three designed siRNAs for IL22 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-147128
CAS No.: 2378039-23-5
PY109 is an orally active and highly selective aryl hydrocarbon receptor (AHR) agonist. PY109's EC50 values in human-derived HepG2 and mouse Hepa-1c1c7 cells are 1.2 nM and 1.4 nM respectively. PY109 significantly upregulates the expression of CYP1A1 and IL-22, and inhibits the expression of IL-17A. PY109 significantly improves colitis in mice. PY109 can be used for research on colitis .
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Cat. No.: HY-RS06737
Research Areas:  

Others

IL22RA1 Human Pre-designed siRNA Set A contains three designed siRNAs for IL22RA1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23295
Research Areas:  

Others

Il22 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il22 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-162490
CAS No.: 2425563-60-4
Target:  

ROR

Research Areas:  

Inflammation/Immunology

TF-S14 is a reverse agonist of RORγt. TF-S14 reduces Th17 cell-associated cytokine production, including IL-17A, IL-21, and IL-22 by binding to and inhibiting RORγt activity. TF-S14 can be used in the study of autoimmune diseases and rejection in allotransplantation .
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Cat. No.: HY-174619
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL22RA1 mRNA encodes the human interleukin 22 receptor subunit alpha 1 (IL22RA1) protein, a member of the class II cytokine receptor family. IL22RA1 has been shown to be a receptor for interleukin 22 (IL22).
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Cat. No.: HY-168971
CAS No.: 1390658-79-3
Synonyms: CP-25
Paeoniflorin-6′-O-benzene sulfonate (CP-25) is the inhibitor for G protein-coupled receptor kinase 2 (GRK2) that inhibits the translocation of GRK2 to the cell membrane, inhibits JAK1/STAT3 signaling pathway. Paeoniflorin-6′-O-benzene sulfonate inhibits IL-17A/CXCL2-induced proliferation of HaCaT. Paeoniflorin-6′-O-benzene sulfonate reduces the levels of inflammatory factors and chemokines such as IL-17A, IL-17F, IFN-γ, TNF-α, IL-22, IL-23, CXCL2, CXCL3 and CXCL9, alleviates Imiquimod (HY-B0180)-induced psoriasis in mouse model .
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Cat. No.: HY-133552
CAS No.: 2413986-35-1
Purity:  99.13%
Target:  

ROR

Research Areas:  

Inflammation/Immunology

RORγt Inverse agonist 10 is a potent and orally bioavailable RORγt (retinoic acid receptor-related orphan nuclear receptor gamma t) inverse agonist, with an IC50 of 51 nM. RORγt is a major transcription factor of genes related to psoriasis pathogenesis such as IL-17A, IL-22, and IL-23R
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Cat. No.: HY-K2109

MCE HOLO Human Interleukin-22 (IL-22) Detection Kit is a homogeneous luminescence-based assay used for the quantitative detection of human IL-22 concentrations in biological samples such as buffer solutions, cell culture supernatants, or serum.

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