37 Results for "

IL33

" in MedChemExpress (MCE) Product Catalog:
Products (37)

37 Results for "IL33" in MCE Product Catalog:

14
14 Publications Verification
Cat. No.: HY-P7218
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuIL-33; IL33
Species:  
Source:  
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4
4 Cited Publications
Cat. No.: HY-P7041
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuIL-33; IL-1F11; NF-HEV; DVS 27
Species:  
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3
3 Cited Publications
Cat. No.: HY-P99444
CAS No.: 2173054-79-8
Synonyms: MSTT 1041A; RG 6149
Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody. Astegolimab blocks IL-33 signaling by targeting the IL-33 receptor ST2. Astegolimab reduces p53 expression, mitigates IL33-upregulated SASP factors such as IL1α, IL6 and MCP1. Astegolimab mitigates IL33-increased p-p65/p65 ratio. Astegolimab blocks CM-induced neutrophil extracellular trap (NET) formation. Astegolimab is used in chronic obstructive pulmonary disease (COPD) and myocardial research .
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1
1 Cited Publications
Cat. No.: HY-P99673
CAS No.: 2226742-52-3
Synonyms: REGN-3500; SAR-440340

Research Areas:  

Inflammation/Immunology

Itepekimab (REGN-3500) is an IgG4 monoclonal antibody against IL-33. Itepekimab reduced airway inflammation and related tissue damage in preliminary clinical studies. Itepekimab has potential effects in asthma, chronic obstructive pulmonary disease (COPD), and atopic dermatitis (AD) .
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1
1 Cited Publications
Cat. No.: HY-P70475
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-33; IL-33; Interleukin-1 FamILy Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HEV; IL33; C9orf26; IL1F11; NFHEV
Species:  
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1
1 Cited Publications
Cat. No.: HY-P70475AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-33; IL-33; Interleukin-1 FamILy Member 11; IL-1F11; Nuclear Factor From High Endothelial Venules; NF-HEV; IL33; C9orf26; IL1F11; NFHEV
Species:  
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1
1 Cited Publications
Cat. No.: HY-P73210
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-33; IL-33; IL-1F11; NF-HEV; DVS 27
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Cat. No.: HY-P2729
CAS No.: 9014-01-1
Synonyms: EC 3.4.21.14
Subtilisin (EC 3.4.21.14) is a bacterial serine protease. Subtilisin induces Apoptosis. Subtilisin stimulates the expression of pro-allergic cytokines (IL-1α, IL-33). Subtilisin induces prototypic allergic lung inflammation. Subtilisin exhibits anticancer activity against breast and colon cancer. Subtilisin shows antifouling activity. Subtilisin can be used as a detergent additive .
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Cat. No.: HY-P991267

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

CAN10 is is a humanized monoclonal antibody inhibitor targeting interleukin 1RAP (IL1RAP). CAN10 blocks IL-1, IL-33, and IL-36 signalling by targeting IL1RAP, preventing downstream proinflammatory and profibrotic responses. CAN10 reduces dermal and pulmonary fibrosis. CAN10 can be used for the research of immune system diseases, such as systemic sclerosis .
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Cat. No.: HY-P99018
CAS No.: 2022981-44-6
Synonyms: Antibody ANB 020

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Etokimab (Antibody ANB 020) is a humanized monoclonal antibody that targets IL-33. Etokimab can be used for the research of atopic dermatitis .
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Cat. No.: HY-168532
CAS No.: 3099811-61-4
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

ST2-IN-1 is a ST2 inhibitor. ST2-IN-1 blocks the binding interaction between ST2 and IL-33, thereby attenuating the downstream ST2/IL-33 signaling pathway. ST2-IN-1 reduces IL-1β release from mast cells and alleviates ST2 upregulation in cells. ST2-IN-1 can be used for research on inflammatory and immune-related diseases .
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Cat. No.: HY-114354
CAS No.: 302795-84-2
Purity:  98.41%
Synonyms: BOD FL alkyne
BODIPY (BOD) FL alkyne is an alkyne-containing BODIPY fluorophore derivative. BODIPY FL alkyne is a bioorthogonal labeling reagent with low toxicity and extremely low non-specific reactivity, and it is widely used in fluorescent bioimaging. BODIPY FL alkyne specifically labels azide groups on intracellular glycoconjugates mainly via strain-promoted azide-alkyne cycloaddition (SPAAC), or mediates site-specific conjugation with proteins such as IL-33, and supports positive cross-linking with other probes (e.g., DBCO-SCy5) for dual labeling. With the advantages of high specificity and low background interference, BODIPY FL alkyne can be used in the research of related diseases such as asthma, atopic dermatitis and inflammatory bowel disease .
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Cat. No.: HY-P99729
CAS No.: 2222865-46-3
Synonyms: GSK 3772847; CNTO-7160

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Melrilimab (GSK 3772847; CNTO-7160) is a humanized IgG2σ monoclonal antibody that targets the IL-33 receptor ST2 and blocks the IL-33/ST2 signaling pathway by binding to the ST2 protein. Melrilimab is applicable to research related to asthma and atopic dermatitis .
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Cat. No.: HY-P990669
CAS No.: 2241728-76-5

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Torudokimab is a humanized antibody expressed in CHO, targeting IL-33. Torudokimab has a huIgG4SP type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145.22 kDa. The isotype control for Torudokimab can refer to Human IgG4 kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-174607
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL33 mRNA encodes the human interleukin 33 (IL33) protein, a cytokine that binds to the IL1RL1/ST2 receptor. IL33 is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells.
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Cat. No.: HY-RS06757
Research Areas:  

Others

IL33 Human Pre-designed siRNA Set A contains three designed siRNAs for IL33 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23101
Research Areas:  

Others

Il33 Rat Pre-designed siRNA Set A contains three designed siRNAs for Il33 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16666
Research Areas:  

Others

Il33 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il33 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991633

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

TQC2938 is a humanized IgG2 monoclonal antibody inhibitor targeting Stimulation-2 (ST2). TQC2938 inhibits the ST2/IL-33 signaling pathway, reduces the level of downstream Th2 cytokines (such as IL-4, IL-5, and IL-13) and eosinophils as well as other inflammatory cells. TQC2938 can be used for inflammatory diseases like asthma research .
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Cat. No.: HY-W060417
CAS No.: 1019158-02-1
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

iST2-1 is an Stimulation-2 (ST2) inhibitor with an IC50 value of 46.65 μM, blocks interaction between ST2 and IL-33, inhibits downstream signaling. iST2-1 functions as an immunomodulator, reduces proliferation of CD4 + and CD8 + T cells, increases regulatory T cell populations, reduces IFN-γ +CD4 + T cell populations, increases Foxp3 +CD4 + regulatory T cell populations in the gastrointestinal tract. iST2-1 reduces plasma soluble ST2 and IFN-γ levels, reduces graft-versus-host disease scores, improves survival in graft-versus-host disease animal models, preserves graft-versus-tumor effect. iST2-1 can be used for the research of graft-versus-host disease .
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