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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
NAGS
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "NAGS" in MCE Product Catalog:
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Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.
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Alkaloids Other Alkaloids Endogenous metabolite Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-173247
CAS No.: 2199491-27-3
Synonyms: ARO-AAT sodium
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Fazirsiran sodium is a second-generation RNAi agent. Fazirsiran sodium consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes . Fazirsiran sodium can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease. AATD is caused by mutations in the alpha-1 antitrypsin (SERPINA1) gene.
Cat. No.: HY-132604
CAS No.: 2175009-08-0
Synonyms: ARO-AAT
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Fazirsiran (ARO-AAT) is a second-generation RNAi agent. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively reduce Alpha1-antitrypsin (AAT) synthesis and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes . Fazirsiran can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease. Alpha-1 antitrypsin deficiency (AATD) is caused by mutations in the alpha-1 antitrypsin (SERPINA1) gene.
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Cat. No.: HY-173246
CAS No.: 2130036-52-9
Cat. No.: HY-173248
CAS No.: 2920438-06-6
Cat. No.: HY-RS09013
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NAGS Human Pre-designed siRNA Set A contains three designed siRNAs for NAGS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-147112
CAS No.: 70622-78-5
Cat. No.: HY-178978
CAS No.: 3051899-13-6
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α,δ-NAG is an orally active glutaminase-resistant less-hydrolyzable L-Glutamine derivative. α,δ-NAG is a G protein-coupled receptor (GPCR) allosteric modulator. α,δ-NAG suppresses neutrophilic airway inflammation by activating the GPCR/ERK/MKP-1 pathway. α,δ-NAG can be used for the researches of inflammation and immunology, such as asthma .
Cat. No.: HY-131275R
CAS No.: 1365802-18-1
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Carglumic Acid (Standard) is the analytical standard of Carglumic Acid. This product is intended for research and analytical applications. Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.
Synonyms: NA-Gly-d8
Cat. No.: HY-RS19356
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Nags Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nags gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25847
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Nags Rat Pre-designed siRNA Set A contains three designed siRNAs for Nags gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-180637
CAS No.: 15383-57-0
Synonyms: N-Acetyl-L-γ-glutamyl phosphate
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Cat. No.: HY-165504
CAS No.: 126844-81-3
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Nagstatin is a naturally derived competitive inhibitor of N-acetyl-β-D-glucosaminidase (NAG-ase), with an IC50 of 0.0012 μg/mL and a Ki of 1.7×10 -8 M against porcine-derived enzyme. Nagstatin enhances cellular immune responses in normal mice and reactivates suppressed cellular immune responses in tumor-bearing mice. Nagstatin can be used in the research of various diseases such as diabetes and leukemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
