1 Result for "

NAMPT dimer interface pocket

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NAMPT dimer interface pocket" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-119159
CAS No.: 361465-74-9
Target:  

NAMPT Caspase Apoptosis

Research Areas:  

Cancer

AS1604498 is a highly specific competitive inhibitor of human NAMPT, with an IC50 of 44.4 nM. AS1604498 functionally inhibits NAMPT enzymatic activity, reduces nicotinamide mononucleotide production, decreases intracellular NAD levels, activates caspase 3/7 and induces cancer cell apoptosis. AS1604498 is applicable to research related to chronic myeloid leukemia .
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