Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
NMB
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "NMB" in MCE Product Catalog:
3
2
2 Cited Publications
Synonyms: CDX-011; CR011-vcMMAE
Research Areas:
Glembatumumab vedotin (CDX-011) is an ADC comprising a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB) and conjugated to the potent tubulinbinding cytotoxic agent MMAE via a protease-sensitive vc linker. Glembatumumab vedotin has potent anticancer effects .
2
1
1 Cited Publications
Cat. No.: HY-P0241
CAS No.: 87096-84-2
Category:
Target:
1
1 Cited Publications
Cat. No.: HY-103277A
Purity: 96.20%
Target:
Research Areas:
Target:
Research Areas:
PD 168368 is a potent, competitive, and selective neuromedin B receptor (NMB-R) antagonist with the Ki of 15–45 nM . PD 168368 is neuromedin B receptor (NMBR; IC50=96 nM) / gastrin-releasing peptide receptor (GRPR IC50=3500 nM) antagonist . PD 168368 also is a mixed FPR1/FPR2/FPR3 agonist with EC50s of 0.57, 0.24, and 2.7 nM, respectively .
Cat. No.: HY-N2600
CAS No.: 76472-87-2
Cat. No.: HY-P5163
CAS No.: 2843557-76-4
Target:
Research Areas:
Cat. No.: HY-103277
CAS No.: 111857-96-6
Target:
Research Areas:
Cat. No.: HY-RS09368
Target:
Research Areas:
NMB Human Pre-designed siRNA Set A contains three designed siRNAs for NMB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-125075
CAS No.: 185215-75-2
Target:
PD 165929 is a high affinity and competitive non-peptide neuromedin-B (NMB) receptor selective antagonist (Ki: 6.3 nM; IC50: 150 nM for rat NMB receptor) .
Cat. No.: HY-RS05648
Target:
Research Areas:
GPNMB Human Pre-designed siRNA Set A contains three designed siRNAs for GPNMB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P992424
Target:
Research Areas:
Cat. No.: HY-RS17137
Target:
Research Areas:
Nmb Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nmb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23583
Target:
Research Areas:
Nmb Rat Pre-designed siRNA Set A contains three designed siRNAs for Nmb gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N2600R
CAS No.: 76472-87-2
Cat. No.: HY-17674
CAS No.: 204067-06-1
Target:
Research Areas:
Bombesin receptor antagonist-1 (Example 32) is a bombesin receptor antagonist with Ki values for neurotide B (NMB receptor) and gastrin-releasing peptide receptor (GRP receptor) of 0.17 and 20 nM respectively. Bombesin receptor antagonist-1 can be used to study various diseases, such as cancer, depression, and eating disorders .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
