![[Leu31,Pro34]-Neuropeptide Y (porcine)](https://file.medchemexpress.com/product_pic/hy-p0208.gif "Click to View [Leu31,Pro34]-Neuropeptide Y (porcine) Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
95 Results for "
NPY
" in MedChemExpress (MCE) Product Catalog:
Products (95)
95 Results for "NPY" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-P0221
CAS No.: 137061-48-4
Synonyms: Pituitary Adenylate Cyclase Activating Polypeptide 38
Research Areas:
4
4 Cited Publications
Target:
Research Areas:
BIBO3304, a chemical probe, is a potent, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist, with subnanomolar affinity for both the human and the rat Y1 receptor (IC50=0.38 and 0.72 nM, respectively) .
2
Target:
Research Areas:
BIIE-0246 (AR-H 053591) is a potent and selective NPY2R (neuropeptide Y receptor 2) antagonist with an IC50 value of 15 nM for rat [ 125I]PYY3-36. BIIE-0246 decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 reduces albuminuria in ADR nephropathy .
2
Target:
Research Areas:
BIIE-0246 hydrochloride (AR-H 053591 hydrochloride) is a potent and selective NPY2R (neuropeptide Y receptor 2) antagonist with an IC50 value of 15 nM for rat [ 125I]PYY3-36. BIIE-0246 hydrochloride decreases the expression of p-AKT S473, P-p44/42 MAPK under the NPY-stimulated. BIIE-0246 hydrochloride reduces albuminuria in ADR nephropathy .
2
1
1 Cited Publications
Target:
Research Areas:
BMS-193885 is a selective neuropeptide Y1 receptor antagonist (Ki=3.3 nM) that competitively blocks the receptor to inhibit NPY-mediated appetite regulation signaling pathways, reduce food intake and inhibit weight gain. BMS-193885 has good blood-brain barrier penetration and is mainly used in the study of obesity and related metabolic diseases .
1
1 Cited Publications
Cat. No.: HY-P0208
CAS No.: 125580-28-1
Target:
Research Areas:
1
Target:
Research Areas:
Velneperit (S-2367) is an orally active neuropeptide Y (NPY) Y5 receptor antagonist that can penetrate the blood-brain barrier. Velneperit inhibits the appetite-stimulating and metabolism-inhibiting effects mediated by NPY. Velneperit selectively improves diet-induced obesity in mice. Velneperit enhances the expression of fear acutely by removing the inhibition of CeA Drd2 neurons. Velneperit can be used for the study of obesity .
1
1 Cited Publications
Target:
Research Areas:
BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect .
Synonyms: MS0015203
Target:
Research Areas:
MS15203 is a potent and selective GPR171 agonist. MS15203 increases food intake and body weight. MS15203 increases neuronal activity. MS15203 significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP .
Target:
Research Areas:
L 152804 is an orally active and selective neuropeptide Y Y5 receptor (NPY5-R) antagonist, with a Ki of 26 nM for hY5. L 152804 causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure .
Cat. No.: HY-P0199
CAS No.: 75976-10-2
Synonyms: Human pancreatic polypeptide
Target:
Research Areas:
Cat. No.: HY-P10026
CAS No.: 2663844-45-7
Synonyms: LY-3457263
Target:
Research Areas:
Cat. No.: HY-P10000
CAS No.: 123583-37-9
Target:
Research Areas:
Target:
Research Areas:
NPY5RA-972 is an orally active, central nervous system (CNS) penetrating, potent and selective NPY Y5 receptor antagonist that prevents feeding driven by activation of this receptor .
Cat. No.: HY-P1845
CAS No.: 138764-85-9
Target:
Research Areas:
Target:
Research Areas:
CYM 9484 is a selective and highly potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM .
Target:
Research Areas:
NTNCB (Compound 11) hydrochloride is a potent and selective neuropeptide Y Y5 (NPY Y5) receptor antagonist with a Ki of 8 nM against human Y5 .
Cat. No.: HY-P4087
CAS No.: 1417221-06-7
Cat. No.: HY-P4123
CAS No.: 1231898-26-2
Target:
Research Areas:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
