NTNCB hydrochloride
Based on 1 Customer Validation
NTNCB (Compound 11) hydrochloride is a potent and selective neuropeptide Y Y5 (NPY Y5) receptor antagonist with a Ki of 8 nM against human Y5.
For research use only. We do not sell to patients.
- Purity: 98.36%
- CAS No.: 191931-56-3
- Formula: C25H34ClN3O4S
- Molecular Weight:508.07
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Neuropeptide Y Receptor Isoforms
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Biological Activity
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hY5 receptor 8 nM (Ki) |
hY1 receptor 16032 nM (Ki) |
Chemical Information
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CAS No. 191931-56-3
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Appearance Solid
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Molecular Weight 508.07
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Formula C25H34ClN3O4S
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Color Off-white to light yellow
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SMILES
O=S(C1=CC=CC=C1[N+]([O-])=O)(NC[C@H]2CC[C@H](CNCC3CC4=C(C=CC=C4)CC3)CC2)=O.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL (246.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9682 mL | 9.8412 mL | 19.6823 mL | 49.2058 mL |
| 5 mM | 0.3936 mL | 1.9682 mL | 3.9365 mL | 9.8412 mL | |
| 10 mM | 0.1968 mL | 0.9841 mL | 1.9682 mL | 4.9206 mL | |
| 15 mM | 0.1312 mL | 0.6561 mL | 1.3122 mL | 3.2804 mL | |
| 20 mM | 0.0984 mL | 0.4921 mL | 0.9841 mL | 2.4603 mL | |
| 25 mM | 0.0787 mL | 0.3936 mL | 0.7873 mL | 1.9682 mL | |
| 30 mM | 0.0656 mL | 0.3280 mL | 0.6561 mL | 1.6402 mL | |
| 40 mM | 0.0492 mL | 0.2460 mL | 0.4921 mL | 1.2301 mL | |
| 50 mM | 0.0394 mL | 0.1968 mL | 0.3936 mL | 0.9841 mL | |
| 60 mM | 0.0328 mL | 0.1640 mL | 0.3280 mL | 0.8201 mL | |
| 80 mM | 0.0246 mL | 0.1230 mL | 0.2460 mL | 0.6151 mL | |
| 100 mM | 0.0197 mL | 0.0984 mL | 0.1968 mL | 0.4921 mL |