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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
Neuroactive
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "Neuroactive" in MCE Product Catalog:
7
7 Publications Verification
Synonyms: SAR442168; PRN2246
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Tolebrutinib (SAR442168) is an orally active, selective, and blood-brain barrier-penetrant BTK inhibitor with neuroactive properties. Tolebrutinib is being investigated for use in multiple sclerosis (MS), particularly secondary progressive multiple sclerosis (SPMS). .
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2 Cited Publications
Synonyms: 17β-Estradiol 3-sulfate sodium
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17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .
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1 Cited Publications
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S 17092 (S 17092-1) is an orally active cerebral prolyl-endopeptidase (PEP) inhibitor with an IC50 of 1.2 nM. S 17092 inhibits cell apoptosis. S 17092 mechanism of action is to inhibit the activity of PEP, slowing down the degradation of neuroactive peptides and thus enhancing memory function. S 17092 can be used for the research of memory impairment and cognitive disorders associated with cerebral aging .
Synonyms: Dimebolin dihydrochloride
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Latrepirdine dihydrochloride is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion.
Synonyms: (2S,6S)-HNK hydrochloride
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(2S,6S)-Hydroxynorketamine hydrochloride is a neurorelaxant with potential antidepressant and analgesic effects. (2S,6S)-Hydroxynorketamine hydrochloride can activate the mTOR pathway, increase the phosphorylation level of downstream targets, and antagonize α7-nicotinic acetylcholine receptor (nAChR) to exert neuroactive properties .
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Art. -Nr.: HY-P3062
CAS. Nr.: 59481-27-5
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Forschungsgebiete:
Latrepirdine is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors. Latrepirdine stimulates amyloid precursor protein (APP) catabolism and amyloid-β (Aβ) secretion.
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KVA-D-88 is a blood-brain barrier-permeable PDE4 inhibitor with IC50 values of 140 and 880 nM for PDE4B and PDE4D, respectively. KVA-D-88 induces cAMP accumulation and inhibits neuroactive substance-mediated hyperlocomotion, locomotor sensitization. KVA-D-88 can be used for the research of drug addiction .
Synonyms: 17β-Estradiol 3-sulfate-d4 sodium
Art. -Nr.: HY-W587827
CAS. Nr.: 3475-65-8
Synonyms: Thiamine triphosphate
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Thiamine triphosphoric acid ester (Thiamine triphosphate) is a neuroactive compound and a triphosphate derivative of vitamin thiamine. Thiamine triphosphoric acid ester exists in microorganisms, animal organs and plants. In E. coli, Thiamine triphosphoric acid ester is transiently produced under amino acid deficiency, while in mammalian cells, it is continuously produced at a low rate. Thiamine triphosphoric acid ester can be synthesized by two distinct enzymes (cytosolic AK1 and FoF1-ATP synthase in brain mitochondria). Thiamine triphosphoric acid ester plays a fundamental role in cellular metabolism or cellular signal transduction .
Art. -Nr.: HY-116105
CAS. Nr.: 14461-91-7
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Cyclazodone is a neuroactive compound .
Synonyms: Co 134444
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Posovolone (Co 134444) is an orally active, neuroactive steroid. Posovolone has anticonvulsant and anxiolytic-like activity as well as ataxic effects .
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Hydroxydione has an effect of general anesthetic. Hydroxydione is a neuroactive steroid it can be used for anaesthesia related research .
Art. -Nr.: HY-129408
CAS. Nr.: 1430064-74-6
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SGE-516 is a neuroactive steroid that is a potent positive allosteric modulator of synaptic and extra-synaptic GABAA receptors. SGE-516 has anticonvulsant activity .
Art. -Nr.: HY-P11082
CAS. Nr.: 126675-52-3
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Art. -Nr.: HY-139388
CAS. Nr.: 1364933-64-1
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Para-fluoro methylaminorex is a neuroactive compound .
Art. -Nr.: HY-W072274
CAS. Nr.: 188398-87-0
Synonyms: (S)-2-Diphenylmethylpyrrolidine hydrochloride
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(S)-Desoxy-D2PM ((S)-2-Diphenylmethylpyrrolidine) hydrochloride is a neuroactive compound.
Art. -Nr.: HY-P3777
CAS. Nr.: 109024-47-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
